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Volumn 54, Issue 1, 2002, Pages 1-12

A method for incorporating ages at onset in affected sibpair linkage studies

Author keywords

Age at onset; Combined test; Maximum; Mean IBD test; Power; Semiparametric model; Type I error rate

Indexed keywords

ANALYTIC METHOD; ANALYTICAL ERROR; ARTICLE; GENE FREQUENCY; GENE LOCATION; GENETIC LINKAGE; GENOTYPE; HUMAN; LATENT PERIOD; ONSET AGE; PEDIGREE; SURVIVAL; CHROMOSOME MAP; STATISTICAL ANALYSIS;

EID: 0036442753     PISSN: 00015652     EISSN: None     Source Type: Journal    
DOI: 10.1159/000066693     Document Type: Article
Times cited : (5)

References (38)
  • 1
    • 0033362231 scopus 로고    scopus 로고
    • Direct power comparisons between simple LOD scores and NPL scores for linkage analysis in complex diseases
    • Abreu PC, Greenberg DA, Hodge SA: Direct power comparisons between simple LOD scores and NPL scores for linkage analysis in complex diseases. Am J Hum Genet 1999;65:847-857.
    • (1999) Am J Hum Genet , vol.65 , pp. 847-857
    • Abreu, P.C.1    Greenberg, D.A.2    Hodge, S.A.3
  • 3
    • 0021957675 scopus 로고
    • A comparison of sibpair linkage tests for disease susceptibility loci
    • Blackwelder WC, Elston RC: A comparison of sib-pair linkage tests for disease susceptibility loci. Genet Epidemiol 1985;2:85-98.
    • (1985) Genet Epidemiol , vol.2 , pp. 85-98
    • Blackwelder, W.C.1    Elston, R.C.2
  • 4
    • 0023694035 scopus 로고
    • Combined linkage and segregation analysis using regression models
    • Bonney GE, Lathrop GM, Lalouel JM: Combined linkage and segregation analysis using regression models. Am J Hum Genet 1988;43:29-37.
    • (1988) Am J Hum Genet , vol.43 , pp. 29-37
    • Bonney, G.E.1    Lathrop, G.M.2    Lalouel, J.M.3
  • 5
    • 0026092912 scopus 로고
    • Genetic analysis of breast cancer in cancer and steroid hormone study
    • Claus EB, Risch N, Thompson WD: Genetic analysis of breast cancer in cancer and steroid hormone study. Am J Hum Genet 1991;48:232-242.
    • (1991) Am J Hum Genet , vol.48 , pp. 232-242
    • Claus, E.B.1    Risch, N.2    Thompson, W.D.3
  • 6
    • 0028220901 scopus 로고
    • Robust genetic linkage analysis based on a score test of homogeneity: The weighted pairwise correlation statistic
    • Commenges D: Robust genetic linkage analysis based on a score test of homogeneity: The weighted pairwise correlation statistic. Genet Epidemiol 1994;11:189-200.
    • (1994) Genet Epidemiol , vol.11 , pp. 189-200
    • Commenges, D.1
  • 7
    • 0000336139 scopus 로고
    • Regression models and life tables
    • Cox DR: Regression models and life tables (with Discussion). J Royal Statist Soc B 1972;34:187-220.
    • (1972) J Royal Statist Soc B , vol.34 , pp. 187-220
    • Cox, D.R.1
  • 8
    • 0035011549 scopus 로고    scopus 로고
    • Segregation analyses of 1,476 population-based Australian families affected by prostate cancer
    • Cui J, Staples MP, Hopper JL, English DR, McCredie MR, Giles GG: Segregation analyses of 1,476 population-based Australian families affected by prostate cancer. Am J Hum Genet 2001;68:1207-1218.
    • (2001) Am J Hum Genet , vol.68 , pp. 1207-1218
    • Cui, J.1    Staples, M.P.2    Hopper, J.L.3    English, D.R.4    McCredie, M.R.5    Giles, G.G.6
  • 9
    • 0025695910 scopus 로고
    • Extensions to sib-pair linkage tests applicable to disorders characterized by delayed onset
    • Dawson DV, Kaplan EB, Elston RC: Extensions to sib-pair linkage tests applicable to disorders characterized by delayed onset. Genet Epidemiol 1990;7:453-466.
    • (1990) Genet Epidemiol , vol.7 , pp. 453-466
    • Dawson, D.V.1    Kaplan, E.B.2    Elston, R.C.3
  • 10
    • 0033365057 scopus 로고    scopus 로고
    • Linkage of type 2 diabetes mellitus and age at onset to a genetic location on chromosome 10q in Mexican Americans
    • Duggirala R, Blangero J, Almasy L, et al: Linkage of type 2 diabetes mellitus and age at onset to a genetic location on chromosome 10q in Mexican Americans. Am J Hum Genet 1999;64:1127-1140.
    • (1999) Am J Hum Genet , vol.64 , pp. 1127-1140
    • Duggirala, R.1    Blangero, J.2    Almasy, L.3
  • 12
    • 0032231937 scopus 로고    scopus 로고
    • The power to detect linkage in complex disease by means of simple LOD-score analyses
    • Greenberg DA, Abreu PC, Hodge SE: The power to detect linkage in complex disease by means of simple LOD-score analyses. Am J Hum Genet 1998;63:870-9.
    • (1998) Am J Hum Genet , vol.63 , pp. 870-879
    • Greenberg, D.A.1    Abreu, P.C.2    Hodge, S.E.3
  • 13
    • 0033361931 scopus 로고    scopus 로고
    • Analysis of affected sib pairs, with covariates - With and without constraints
    • Greenwood CMT, Bull SB: Analysis of affected sib pairs, with covariates - With and without constraints. Am J Hum Genet 1999;64:871-885.
    • (1999) Am J Hum Genet , vol.64 , pp. 871-885
    • Greenwood, C.M.T.1    Bull, S.B.2
  • 15
    • 0015309467 scopus 로고
    • The investigation of linkage between a quantitative trait and a marker locus
    • Haseman JK, Elston RC: The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 1972;2:3-19.
    • (1972) Behav Genet , vol.2 , pp. 3-19
    • Haseman, J.K.1    Elston, R.C.2
  • 16
    • 0021669736 scopus 로고
    • The information contained in multiple sibling pairs
    • Hodge SE: The information contained in multiple sibling pairs. Genet Epidemiol 1984;1:109-122.
    • (1984) Genet Epidemiol , vol.1 , pp. 109-122
    • Hodge, S.E.1
  • 17
    • 0028029930 scopus 로고
    • Lods, Wrods and Mods: The interpretation of lod scores calculated under different models
    • Hodge SE, Elston RC: Lods, Wrods and Mods: The interpretation of lod scores calculated under different models. Genet Epidemiol 1994;11:329-342.
    • (1994) Genet Epidemiol , vol.11 , pp. 329-342
    • Hodge, S.E.1    Elston, R.C.2
  • 19
    • 0029886532 scopus 로고    scopus 로고
    • Parametric and nonparametric linkage analysis: A unified multipoint approach
    • Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES: Parametric and nonparametric linkage analysis: A unified multipoint approach. Am J Hum Genet 1996;58:1347-1363.
    • (1996) Am J Hum Genet , vol.58 , pp. 1347-1363
    • Kruglyak, L.1    Daly, M.J.2    Reeve-Daly, M.P.3    Lander, E.S.4
  • 20
    • 0028090414 scopus 로고
    • Genetic dissection of complex traits
    • Lander ES, Schork NJ: Genetic dissection of complex traits. Science 1994;265:2037-2048.
    • (1994) Science , vol.265 , pp. 2037-2048
    • Lander, E.S.1    Schork, N.J.2
  • 21
    • 0030985592 scopus 로고    scopus 로고
    • Semiparametric estimation of major gene and random familial effects for age of onset
    • Li H, Thompson EA: Semiparametric estimation of major gene and random familial effects for age of onset. Biometrics 1997;53:282-293.
    • (1997) Biometrics , vol.53 , pp. 282-293
    • Li, H.1    Thompson, E.A.2
  • 22
    • 0033821107 scopus 로고    scopus 로고
    • Effects of ages at onset on the power of affected sibpair and transmission disequilibrium tests
    • Li H, Hsu L: Effects of ages at onset on the power of affected sibpair and transmission disequilibrium tests. Ann Hum Genet 2000;64:239-254.
    • (2000) Ann Hum Genet , vol.64 , pp. 239-254
    • Li, H.1    Hsu, L.2
  • 23
    • 0032969483 scopus 로고    scopus 로고
    • Optimal allele-sharing statistics for genetic mapping using affected relatives
    • McPeek MS: Optimal allele-sharing statistics for genetic mapping using affected relatives. Genet Epidemiol 1999;16:225-249.
    • (1999) Genet Epidemiol , vol.16 , pp. 225-249
    • McPeek, M.S.1
  • 24
    • 0028113345 scopus 로고
    • A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
    • Miki Y, Swensen J, Shattuck-Eidens D, et al: A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994;266:66-71.
    • (1994) Science , vol.266 , pp. 66-71
    • Miki, Y.1    Swensen, J.2    Shattuck-Eidens, D.3
  • 25
    • 0028046935 scopus 로고
    • Robust estimation of gene frequency and association parameters
    • Olson J: Robust estimation of gene frequency and association parameters. Biometrics 1994;50:665-674.
    • (1994) Biometrics , vol.50 , pp. 665-674
    • Olson, J.1
  • 26
    • 0033362153 scopus 로고    scopus 로고
    • A general conditional-logistic model for affected-relative-pair linkage studies
    • Olson J: A general conditional-logistic model for affected-relative-pair linkage studies. Am J Hum Genet 1999;65:1760-1769.
    • (1999) Am J Hum Genet , vol.65 , pp. 1760-1769
    • Olson, J.1
  • 28
    • 0025008677 scopus 로고
    • Linkage strategies for genetically complex traits. II. The power of affected relative pairs
    • Risch N: Linkage strategies for genetically complex traits. II. The power of affected relative pairs. Am J Hum Genet 1990;46:229-242.
    • (1990) Am J Hum Genet , vol.46 , pp. 229-242
    • Risch, N.1
  • 29
    • 0033850292 scopus 로고    scopus 로고
    • Variance component analysis for pedigree-based censored survival data using weighted linear mixed models (GLMMS) and Gibbs sampling in BUGS
    • Scurrah KJ, Palmer LJ, Burton PR: Variance component analysis for pedigree-based censored survival data using weighted linear mixed models (GLMMS) and Gibbs sampling in BUGS. Genet Epidemiol 2000;19:127-148.
    • (2000) Genet Epidemiol , vol.19 , pp. 127-148
    • Scurrah, K.J.1    Palmer, L.J.2    Burton, P.R.3
  • 31
    • 0001522212 scopus 로고    scopus 로고
    • Modeling hazard functions in families
    • Siegmund K, McKnight B: Modeling hazard functions in families. Genet Epidemiol 1998;15:147-171.
    • (1998) Genet Epidemiol , vol.15 , pp. 147-171
    • Siegmund, K.1    McKnight, B.2
  • 32
    • 0033961305 scopus 로고    scopus 로고
    • Linkage analysis for diseases with variable age of onset
    • Siegmund KD, Todorov AA: Linkage analysis for diseases with variable age of onset. Hum Hered 1998;50:205-210.
    • (1998) Hum Hered , vol.50 , pp. 205-210
    • Siegmund, K.D.1    Todorov, A.A.2
  • 33
    • 0018150112 scopus 로고
    • The weighted sib pair IBD distribution: Its use in the detection of linkage
    • Suarez BK, Rice J, Reich T: The weighted sib pair IBD distribution: Its use in the detection of linkage. Ann Hum Genet 1978;42:87-94.
    • (1978) Ann Hum Genet , vol.42 , pp. 87-94
    • Suarez, B.K.1    Rice, J.2    Reich, T.3
  • 34
    • 0023894935 scopus 로고
    • The affected-pedigree-member method of linkage analysis
    • Weeks DE, Lang K: The affected-pedigree-member method of linkage analysis. Am J Hum Genet 1988;42:315-326.
    • (1988) Am J Hum Genet , vol.42 , pp. 315-326
    • Weeks, D.E.1    Lang, K.2
  • 35
    • 0029737799 scopus 로고    scopus 로고
    • Genome scanning for linkage: An overview
    • Whittemore AS: Genome scanning for linkage: An overview. Am J Hum Genet 1996;59:704-716.
    • (1996) Am J Hum Genet , vol.59 , pp. 704-716
    • Whittemore, A.S.1
  • 38
    • 0032486145 scopus 로고    scopus 로고
    • An efficient, robust and unified framework for mapping complex traits (I): Two-point analysis
    • Zhao LP, Quiaoit F, Hsu L, Aragaki C: An efficient, robust and unified framework for mapping complex traits (I): Two-point analysis. Am J Med Genet 1998;77:366-383.
    • (1998) Am J Med Genet , vol.77 , pp. 366-383
    • Zhao, L.P.1    Quiaoit, F.2    Hsu, L.3    Aragaki, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.