메뉴 건너뛰기




Volumn 77, Issue 5, 1998, Pages 366-383

Efficient, robust, and unified method for mapping complex traits (I): Two-point linkage analysis

Author keywords

Binary phenotype; Censored phenotype; Complex traits; Continuous phenotype; Estimating equation; Gene environmental interaction; Gene gene interaction; Linkage; Lod score; Mapping; Maximum likelihood; Score estimating equation; Segregation

Indexed keywords

ALGORITHM; ARTICLE; ENVIRONMENTAL FACTOR; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENETIC LINKAGE; PEDIGREE; PHENOTYPE; PRIORITY JOURNAL; SCORING SYSTEM; SEGREGATION ANALYSIS;

EID: 0032486145     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19980605)77:5<366::AID-AJMG5>3.0.CO;2-L     Document Type: Article
Times cited : (9)

References (39)
  • 1
    • 0027461201 scopus 로고
    • Robustness of the maximum-likelihood (LOD) method for detecting linkage
    • Amos CI, Williamson JA (1993): Robustness of the maximum-likelihood (LOD) method for detecting linkage. Am J Hum Genet 52:142-143.
    • (1993) Am J Hum Genet , vol.52 , pp. 142-143
    • Amos, C.I.1    Williamson, J.A.2
  • 2
    • 0023278874 scopus 로고
    • Segregation and linkage analyses of dopamine-B-hydroxylase activity in a six-generation pedigree
    • Asamoah A, Wilson AF, Elston RC, Dalferes JR, Gerenson GS (1987): Segregation and linkage analyses of dopamine-B-hydroxylase activity in a six-generation pedigree. Am J Med Genet 27:613-621.
    • (1987) Am J Med Genet , vol.27 , pp. 613-621
    • Asamoah, A.1    Wilson, A.F.2    Elston, R.C.3    Dalferes, J.R.4    Gerenson, G.S.5
  • 3
    • 0029611019 scopus 로고
    • The GAW9 breast cancer linkage data set
    • Bishop DT (1995): The GAW9 breast cancer linkage data set. Genet Epidemiol 12:837-840.
    • (1995) Genet Epidemiol , vol.12 , pp. 837-840
    • Bishop, D.T.1
  • 4
    • 0022770246 scopus 로고
    • Regressive logistic models for familial disease and other binary traits
    • Bonney GE (1986): Regressive logistic models for familial disease and other binary traits. Biometrics 42:611-625.
    • (1986) Biometrics , vol.42 , pp. 611-625
    • Bonney, G.E.1
  • 6
    • 0000336139 scopus 로고
    • Regression models and life-tables
    • Cox DR (1972): Regression models and life-tables (with discussion). J R Stat Soc (B)4:187-220.
    • (1972) J R Stat Soc (B) , vol.4 , pp. 187-220
    • Cox, D.R.1
  • 7
  • 9
    • 0027433563 scopus 로고
    • Genetic linkage analysis in familial breast and ovarian cancer: Results from 214 families
    • Easton DF, Bishop DT, Ford D, Crockford GP, Breast Cancer Linkage Consortium (1993): Genetic linkage analysis in familial breast and ovarian cancer: Results from 214 families. Am J Hum Genet 52:678-701.
    • (1993) Am J Hum Genet , vol.52 , pp. 678-701
    • Easton, D.F.1    Bishop, D.T.2    Ford, D.3    Crockford, G.P.4    Consortium, B.C.L.5
  • 10
    • 0344470627 scopus 로고
    • Modern methods of segregation analysis
    • Moolgavkar SH, Prentice RL (eds): Canada: John Wiley & Sons
    • Elston RC (1986): Modern methods of segregation analysis. In Moolgavkar SH, Prentice RL (eds): "Modern Statistical Methods in Chronic Disease Epidemiology." Canada: John Wiley & Sons, pp 213-224.
    • (1986) Modern Statistical Methods in Chronic Disease Epidemiology , pp. 213-224
    • Elston, R.C.1
  • 11
    • 0018409037 scopus 로고
    • Sampling considerations in the gathering and analysis of pedigree data
    • Elston RC, Sobel E (1979): Sampling considerations in the gathering and analysis of pedigree data. Am J Hum Genet 31:62-69.
    • (1979) Am J Hum Genet , vol.31 , pp. 62-69
    • Elston, R.C.1    Sobel, E.2
  • 12
    • 0015183542 scopus 로고
    • A general model for the genetic analysis of pedigree data
    • Elston RC, Stewart J (1971): A general model for the genetic analysis of pedigree data. Human Heredity 21:523-542.
    • (1971) Human Heredity , vol.21 , pp. 523-542
    • Elston, R.C.1    Stewart, J.2
  • 13
    • 0000178021 scopus 로고
    • The combination of linkage values, and the calculation of distances between the loci of linked factors
    • Haldane JBS (1919): The combination of linkage values, and the calculation of distances between the loci of linked factors. J Genet 8:299-309.
    • (1919) J Genet , vol.8 , pp. 299-309
    • Haldane, J.B.S.1
  • 15
  • 16
    • 0028857541 scopus 로고
    • Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping
    • Kruglyak L, Daly MJ, Lander ES (1995): Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping. Am J Hum Genet 56:519-527.
    • (1995) Am J Hum Genet , vol.56 , pp. 519-527
    • Kruglyak, L.1    Daly, M.J.2    Lander, E.S.3
  • 17
    • 0028952250 scopus 로고
    • High-resolution genetic mapping of complex traits
    • Kruglyak L, Lander ES (1995a): High-resolution genetic mapping of complex traits. Am J Hum Genet 56:1212-1223.
    • (1995) Am J Hum Genet , vol.56 , pp. 1212-1223
    • Kruglyak, L.1    Lander, E.S.2
  • 18
    • 0029046177 scopus 로고
    • Complete multipoint sib-pair analysis of qualitative and quantitative traits
    • Kruglyak L, Lander ES (1995b): Complete multipoint sib-pair analysis of qualitative and quantitative traits. Am J Hum Genet 57:439-454.
    • (1995) Am J Hum Genet , vol.57 , pp. 439-454
    • Kruglyak, L.1    Lander, E.S.2
  • 19
    • 0028090414 scopus 로고
    • Genetic dissection of complex traits
    • Lander ES, Schork NJ (1994): Genetic dissection of complex traits. Science 265:2037-2048.
    • (1994) Science , vol.265 , pp. 2037-2048
    • Lander, E.S.1    Schork, N.J.2
  • 20
    • 77649173768 scopus 로고
    • Longitudinal data analysis using generalized linear models
    • Liang KY, Zeger SL (1986): Longitudinal data analysis using generalized linear models. Biometrika 73:13-22.
    • (1986) Biometrika , vol.73 , pp. 13-22
    • Liang, K.Y.1    Zeger, S.L.2
  • 24
    • 0029001682 scopus 로고
    • Extreme discordant sib pairs for mapping quantitiative trait loci in humans
    • Risch N, Zhang H (1995): Extreme discordant sib pairs for mapping quantitiative trait loci in humans. Science 268:1584-1589.
    • (1995) Science , vol.268 , pp. 1584-1589
    • Risch, N.1    Zhang, H.2
  • 25
    • 0027430716 scopus 로고
    • Two-trait-locus link-age analysis: A powerful strategy for mapping complex genetic traits
    • Schork NJ, Boehnke M, Tenvilliger JD, Ott J (1993): Two-trait-locus link-age analysis: A powerful strategy for mapping complex genetic traits. Am J Hum Genet 53:1127-1136.
    • (1993) Am J Hum Genet , vol.53 , pp. 1127-1136
    • Schork, N.J.1    Boehnke, M.2    Tenvilliger, J.D.3    Ott, J.4
  • 27
    • 84907319426 scopus 로고
    • Asymptotic properties of maximum likelihood estimators and likelihood ratio tests under nonstandard conditions
    • Self SG, Liang KY (1987): Asymptotic properties of maximum likelihood estimators and likelihood ratio tests under nonstandard conditions. J Am Stat Assoc 82:605-610.
    • (1987) J Am Stat Assoc , vol.82 , pp. 605-610
    • Self, S.G.1    Liang, K.Y.2
  • 28
    • 0029846120 scopus 로고    scopus 로고
    • Identifying marker typing incompatibilities in linkage analysis
    • Stringham HM, Boehnke M (1996): Identifying marker typing incompatibilities in linkage analysis. Am J Hum Genet 59:946-950.
    • (1996) Am J Hum Genet , vol.59 , pp. 946-950
    • Stringham, H.M.1    Boehnke, M.2
  • 29
    • 0026528757 scopus 로고
    • A Gibbs sampling approach to linkage analysis
    • Thomas DC, Cortessis V (1992): A Gibbs sampling approach to linkage analysis. Hum Hered 42:63-76.
    • (1992) Hum Hered , vol.42 , pp. 63-76
    • Thomas, D.C.1    Cortessis, V.2
  • 31
    • 84972506925 scopus 로고
    • Monte carlo likelihood in genetic mapping
    • Thompson EA (1994): Monte carlo likelihood in genetic mapping. Stat Sci 9:355-366.
    • (1994) Stat Sci , vol.9 , pp. 355-366
    • Thompson, E.A.1
  • 32
    • 0028873796 scopus 로고
    • Inherent intractability of the ascertainment problem for pedigree data: A general likelihood framework
    • Vieland VJ, Hodge SE (1995): Inherent intractability of the ascertainment problem for pedigree data: A general likelihood framework. Am J Hum Genet 56:33-43.
    • (1995) Am J Hum Genet , vol.56 , pp. 33-43
    • Vieland, V.J.1    Hodge, S.E.2
  • 33
    • 0000677731 scopus 로고
    • The theory of multiple-strand crossing over
    • Weinstein A (1936): The theory of multiple-strand crossing over. Genetics 21:155-199.
    • (1936) Genetics , vol.21 , pp. 155-199
    • Weinstein, A.1
  • 34
    • 0029737799 scopus 로고    scopus 로고
    • Genome scanning for linkage: An overview
    • Whittemore AS (1996): Genome scanning for linkage: An overview. Am J Hum Genet 59:704-716.
    • (1996) Am J Hum Genet , vol.59 , pp. 704-716
    • Whittemore, A.S.1
  • 35
    • 0023903545 scopus 로고
    • Linkage of a gene regulating dopamine-beta-hydroxylase activity and the ABO blood group locus
    • Wilson AF, Elston RC, Siervogel RM, Tran LD (1988): Linkage of a gene regulating dopamine-beta-hydroxylase activity and the ABO blood group locus. Am J Hum Genet 42:160-166.
    • (1988) Am J Hum Genet , vol.42 , pp. 160-166
    • Wilson, A.F.1    Elston, R.C.2    Siervogel, R.M.3    Tran, L.D.4
  • 36
    • 0028066158 scopus 로고
    • Segregation analysis of human pedigrees using estimating equations
    • Zhao LP (1994): Segregation analysis of human pedigrees using estimating equations. Biometrika 81:197-209.
    • (1994) Biometrika , vol.81 , pp. 197-209
    • Zhao, L.P.1
  • 37
    • 0030871697 scopus 로고    scopus 로고
    • Population-based family study designs: An interdisciplinary research framework for genetic epidemiology
    • Zhao LP, Hsu L, Davidov O, Potter J, Prentice RL (1997): Population-based family study designs: An interdisciplinary research framework for genetic epidemiology. Genet Epidemiol 14:365-388.
    • (1997) Genet Epidemiol , vol.14 , pp. 365-388
    • Zhao, L.P.1    Hsu, L.2    Davidov, O.3    Potter, J.4    Prentice, R.L.5
  • 38
    • 12244310929 scopus 로고
    • Correlated binary regression using a quadratic exponential model
    • Zhao LP, Prentice RL (1990): Correlated binary regression using a quadratic exponential model. Biometrika 77:642-648.
    • (1990) Biometrika , vol.77 , pp. 642-648
    • Zhao, L.P.1    Prentice, R.L.2
  • 39
    • 0025078114 scopus 로고
    • Joint estimation of recombination fractions and interference coefficients in multilocus linkage analysis
    • Zhao LP, Thompson EA, Prentice RL (1990): Joint estimation of recombination fractions and interference coefficients in multilocus linkage analysis. Am J Hum Genet 47:255-265.
    • (1990) Am J Hum Genet , vol.47 , pp. 255-265
    • Zhao, L.P.1    Thompson, E.A.2    Prentice, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.