Apoptosis in the pathogenesis of renal disease with a focus on tubulointerstitial injury

Nephrology

Volumn 7, Issue 6, 2002, Pages 287-293

  Gobe, Glenda ^a   Buttyan, Ralph ^b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

Author keywords

Cell death; Inflammation; Necrosis; Renal failure; Renal fibrosis

Indexed keywords

APOPTOSIS; CELL FUNCTION; CELL LOSS; CELL PROLIFERATION; DISEASE COURSE; HOMEOSTASIS; HUMAN; IMMUNOPATHOLOGY; INFLAMMATION; KIDNEY CELL; KIDNEY DEVELOPMENT; KIDNEY DISEASE; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY ISCHEMIA; NEPHROTOXICITY; PATHOGENESIS; PRIORITY JOURNAL; PUBLICATION; RADIATION INJURY; REVIEW;

EID: 0036439153     PISSN: 13205358     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1797.2002.00126.x     Document Type: Review

References (35)

1. Gobe GC, Axelsen RA. Genesis of renal tubular atrophy in experimental hydronephrosis in the rat. Role of apoptosis. Lab. Invest. 1987; 56: 273-81.
2. Kerr JF, Wyllie AH, Currie AR. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 1972; 26: 239-57.
3. Lieberthal W, Koh JS, Levine JS. Necrosis and apoptosis in acute renal failure. Semin. Nephrol. 1998; 18: 505-18.
4. Kerr JF, Gobe GC, Winterford CM, Harmon BV. Anatomical methods in cell death. Meth. Cell. Biol. 1995; 46: 1-27.
5. Gobe G, Zhang XJ, Cuttle L et al. Bcl-2 genes and growth factors in the pathology of ischaemic acute renal failure. Immunol. Cell. Biol. 1999; 77: 279-86.
6. Saikumar P, Dong Z, Weinberg JM, Venkatachalam MA. Mechanisms of cell death in hypoxia/reoxygenation injury. Oncogene 1998; 17: 3341-9.
7. van de Water B, Houtepen F, Huigsloot M, Tijdens IB. Suppression of chemically induced apoptosis but not necrosis of renal proximal tubular epithelial (LLC-PK1) cells by focal adhesion kinase (FAK). Role of FAK in maintaining focal adhesion organization after acute renal cell injury. J. Biol. Chem. 2001; 276: 36 183-93.
8. Buttyan R, Gobe G. Apoptosis in the mammalian kidney: Incidence, effectors, and molecular control in normal development and disease states. Adv. Pharmacol. 1997; 41: 369-81.
9. Racusen LC, Fivush BA, Li YL, Slatnik I, Solez K. Dissociation of tubular cell detachment and tubular cell death in clinical and experimental 'acute tubular necrosis'. Lab. Invest. 1991; 64: 546-56.
10. Park M, Lee R, Lee S, Jung JS. Apoptosis induced by inhibition of contact with extracellular matrix in mouse collecting duct cells. Nephron 1999; 83: 341-51.
11. Bachelder R, Wendt M, Fujita N, Tsurou T, Mercurio A. The cleavage of Akt/protein kinase B by death receptor signalling is an important event in detachment-induced apoptosis. J. Biol. Chem. 2001; 276: 34 072-7.
12. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell. Biol. 1992; 119: 493-501.
13. Ansari B, Coates PJ, Greenstein BD, Hall PA. In situ end-labelling detects DNA strand breaks in apoptosis and other physiological and pathological states. J. Pathol. 1993; 170: 1-8.
14. Chiu PM, Ngan YS, Khoo US, Cheung AN. Apoptotic activity in gestational trophoblastic disease correlates with clinical outcome: Assessment by the caspase-related M30 CytoDeath antibody. Histopathology 2001; 38: 243-9.
15. Kadyrov M, Kaufmann P, Huppertz B. Expression of a cytokeratin 18 neo-epitope is a specific marker for trophoblast apoptosis in human placenta. Placenta 2001; 22: 44-8.
16. Zager RA, Fuerstenberg SM, Baehr PH, Myerson D, Torok-Storb B. An evaluation of antioxidant effects on recovery from postischemic acute renal failure. J. Am. Soc. Nephrol. 1994; 4: 1588-97.
17. Beeri R, Symon Z, Brezis M et al. Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys. Kidney Int. 1995; 47: 1806-10.
18. Gobe G, Zhang XJ, Willgoss DA et al. Relationship between expression of Bcl-2 genes and growth factors in ischemic acute renal failure in the rat. J. Am. Soc. Nephrol. 2000; 11: 454-67.
19. Buttyan R, Olsson CA, Pintar J et al. Induction of the TRPM-2 gene in cells undergoing programmed death. Mol. Cell. Biol. 1989; 9: 3473-81.
20. Sawczuk IS, Hoke G, Olsson CA, Connor J, Buttyan R. Gene expression in response to acute unilateral ureteral obstruction. Kidney Int. 1989; 35: 1315-19.
21. Humphreys DT, Carver JA, Easterbrook-Smith SB, Wilson MR. Clusterin has chaperone-like activity similar to that of small heat shock proteins. J. Biol. Chem. 1999; 274: 6875-81.
22. Truong LD, Choi YJ, Tsao CC et al. Renal cell apoptosis in chronic obstructive uropathy: The roles of caspases. Kidney Int. 2001; 60: 924-34.
23. Lorz C, Ortiz A, Justo P et al. Proapoptotic Fas ligand is expressed by normal kidney tubular epithelium and injured glomeruli. J. Am. Soc. Nephrol. 2000; 11: 1266-77.
24. Verrey F, Pearce D, Pfeiffer R et al. Pleiotropic action of aldosterone in epithelia mediated by transcription and post-transcription mechanisms. Kidney Int. 2000; 57: 1277-82.
25. Zhan Y, Cleveland JL, Stevens JL. A role for c-myc in chemically induced renal-cell death. Mol. Cell. Biol. 1997; 17: 6755-64.
26. Force T, Bonventre JV. Growth factors and mitogen-activated protein kinases. Hypertension 1998; 31: 152-61.
27. Adams JM, Cory S. The Bcl-2 protein family: Arbiters of cell survival. Science 1998; 281: 1322-6.
28. Kelekar A, Thompson CB. Bcl-2-family proteins: The role of the BH3 domain in apoptosis. Trends Cell. Biol. 1998; 8: 324-30.
29. Cuttle L, Zhang XJ, Endre ZH, Winterford C, Gobe GC. Bcl-X (L) translocation in renal tubular epithelial cells in vitro protects distal cells from oxidative stress. Kidney Int. 2001; 59: 1779-88.
30. el Nahas AM, Muchaneta-Kubara EC, Essawy M, Soylemezoglu O. Renal fibrosis: Insights into the pathogenesis and treatment. Int. J. Biochem. Cell Biol. 1997; 29: 55-62.
31. Eddy A. Molecular basis of renal fibrosis. Pediatr. Nephrol. 2000; 15: 290-301.
32. Brezis M, Shanley P, Silva P et al. Disparate mechanisms for hypoxic cell injury in different nephron segments. Studies in the isolated perfused rat kidney. J. Clin. Invest. 1985; 76: 1796-806.
33. Savill J. Apoptosis in resolution of inflammation. Kidney Blood Press. Res. 2000; 23: 173-4.
34. Goumenos D, Tsomi K, Iatrou C et al. Myofibroblasts and the progression of crescentic glomerulonephritis. Nephrol. Dial. Transplant. 1998; 13: 1652-61.
35. Lane A, Pat B, Johnson DW et al. Interacting roles of myofibroblasts, apoptosis and fibrogenic growth factors in the pathogenesis of renal tubulo-interstitial fibrosis. Growth Factors, in press.