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Volumn 268, Issue 3, 2002, Pages 352-361

Functional analysis of mlcR, a regulatory gene for ML-236B (compactin) biosynthesis in Penicillium citrinum

Author keywords

Gene regulation; ML 236B biosynthesis; Penicillium citrinum

Indexed keywords

COMPACTIN; PHOSPHOGLYCERATE KINASE;

EID: 0036435880     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00438-002-0755-5     Document Type: Article
Times cited : (39)

References (38)
  • 1
    • 0036321084 scopus 로고    scopus 로고
    • Molecular cloning and characterization of an ML-236B (compactin) biosynthetic gene cluster in Penicillium citrinum
    • Abe Y, Suzuki T, Ono C, Iwamoto K, Hosobuchi M, Yoshikawa H (2002a) Molecular cloning and characterization of an ML-236B (compactin) biosynthetic gene cluster in Penicillium citrinum. Mol Genet Genomics 267:636-646
    • (2002) Mol Genet Genomics , vol.267 , pp. 636-646
    • Abe, Y.1    Suzuki, T.2    Ono, C.3    Iwamoto, K.4    Hosobuchi, M.5    Yoshikawa, H.6
  • 2
    • 0036384909 scopus 로고    scopus 로고
    • Effect of increased dosage of the ML-236B (compactin) biosynthetic gene cluster on ML-236B production in Penicillium citrinum
    • Abe Y, Suzuki T, Mizuno T, Ono C, Iwamoto K, Yoshikawa H. (2002b) Effect of increased dosage of the ML-236B (compactin) biosynthetic gene cluster on ML-236B production in Penicillium citrinum. Mol Genet Genomics 268:130-137
    • (2002) Mol Genet Genomics , vol.268 , pp. 130-137
    • Abe, Y.1    Suzuki, T.2    Mizuno, T.3    Ono, C.4    Iwamoto, K.5    Yoshikawa, H.6
  • 3
    • 0031975577 scopus 로고    scopus 로고
    • The TRI11 gene of Fusarium sporotrichioides encodes a cytochrome P-450 monooxygenase required for C-15 hydroxylation in trichothecene biosynthesis
    • Alexander NJ, Hohn TM, McCormick SP (1998) The TRI11 gene of Fusarium sporotrichioides encodes a cytochrome P-450 monooxygenase required for C-15 hydroxylation in trichothecene biosynthesis. Appl Environ Microbiol 64:21-225
    • (1998) Appl Environ Microbiol , vol.64 , pp. 21-225
    • Alexander, N.J.1    Hohn, T.M.2    McCormick, S.P.3
  • 4
    • 0016913421 scopus 로고
    • Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum
    • Brown AG, Smale TC, King TJ, Hasenkamp R, Thompson RH (1976) Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum. J Chem Soc Perkin Trans 1:1165-1170
    • (1976) J Chem Soc Perkin Trans , vol.1 , pp. 1165-1170
    • Brown, A.G.1    Smale, T.C.2    King, T.J.3    Hasenkamp, R.4    Thompson, R.H.5
  • 5
    • 0023652092 scopus 로고
    • Isolation and characterization of the positively acting regulatory gene QUTA from Aspergillus nidulans
    • Beri RK, Whittington H, Roberts CF, Hawkins AR (1987) Isolation and characterization of the positively acting regulatory gene QUTA from Aspergillus nidulans. Nucleic Acids Res 15:7991-8001
    • (1987) Nucleic Acids Res , vol.15 , pp. 7991-8001
    • Beri, R.K.1    Whittington, H.2    Roberts, C.F.3    Hawkins, A.R.4
  • 7
    • 0029079145 scopus 로고
    • Increased expression of Aspergillus parasiticus aflR, encoding a sequence-specific DNA-binding protein, relieves nitrate inhibition of aflatoxin biosynthesis
    • Chang PK, Ehrlich KC, Yu J, Bhatnagar D, Cleveland TE (1995) Increased expression of Aspergillus parasiticus aflR, encoding a sequence-specific DNA-binding protein, relieves nitrate inhibition of aflatoxin biosynthesis. Appl Environ Microbiol 61:2372-2377
    • (1995) Appl Environ Microbiol , vol.61 , pp. 2372-2377
    • Chang, P.K.1    Ehrlich, K.C.2    Yu, J.3    Bhatnagar, D.4    Cleveland, T.E.5
  • 8
    • 0021942026 scopus 로고
    • Molecular cloning of the 3-phosphoglycerate kinase (PGK) gene from Aspergillus nidulans
    • Clements JM, Roberts CF (1985) Molecular cloning of the 3-phosphoglycerate kinase (PGK) gene from Aspergillus nidulans. Curr Genet 9:293-298
    • (1985) Curr Genet , vol.9 , pp. 293-298
    • Clements, J.M.1    Roberts, C.F.2
  • 9
    • 0022512096 scopus 로고
    • Transcription and processing signals in the 3-phosphoglycerate kinase (PGK) gene from Aspergillus nidulans
    • Clements JM, Roberts CF (1986) Transcription and processing signals in the 3-phosphoglycerate kinase (PGK) gene from Aspergillus nidulans. Gene 44:97-105
    • (1986) Gene , vol.44 , pp. 97-105
    • Clements, J.M.1    Roberts, C.F.2
  • 10
    • 0028848859 scopus 로고
    • A cluster of cytochrome P450 genes of the CYP6 family in the house fly
    • Cohen MB, Feyereisen R (1995) A cluster of cytochrome P450 genes of the CYP6 family in the house fly. DNA Cell Biol 14:73-82
    • (1995) DNA Cell Biol , vol.14 , pp. 73-82
    • Cohen, M.B.1    Feyereisen, R.2
  • 11
    • 0017055252 scopus 로고
    • ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinum
    • Endo A, Kuroda M, Tsujita M (1976) ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinum. J Antibiot 29:1346-1348
    • (1976) J Antibiot , vol.29 , pp. 1346-1348
    • Endo, A.1    Kuroda, M.2    Tsujita, M.3
  • 12
    • 0033574753 scopus 로고    scopus 로고
    • Binding of the C6-zinc cluster protein, AFLR, to the promoters of aflatoxin pathway biosynthesis genes in Aspergillus parasiticus
    • Ehrlich KC, Montalbano BG, Cary JW (1999) Binding of the C6-zinc cluster protein, AFLR, to the promoters of aflatoxin pathway biosynthesis genes in Aspergillus parasiticus. Gene 230:249-57
    • (1999) Gene , vol.230 , pp. 249-257
    • Ehrlich, K.C.1    Montalbano, B.G.2    Cary, J.W.3
  • 13
    • 0030756319 scopus 로고    scopus 로고
    • Overexpression of aflR leads to upregulation of pathway gene transcription and increased aflatoxin production in Aspergillus flavus
    • Flaherty JE, Payne GA (1997) Overexpression of aflR leads to upregulation of pathway gene transcription and increased aflatoxin production in Aspergillus flavus. Appl Environ Microbiol 63:3995-4000
    • (1997) Appl Environ Microbiol , vol.63 , pp. 3995-4000
    • Flaherty, J.E.1    Payne, G.A.2
  • 14
    • 0021078994 scopus 로고
    • Plasmid-encoded hygromycin B resistance: The sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae
    • Gritz L, Davies J (1983) Plasmid-encoded hygromycin B resistance: The sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae. Gene 25:179-188
    • (1983) Gene , vol.25 , pp. 179-188
    • Gritz, L.1    Davies, J.2
  • 15
    • 0000812578 scopus 로고
    • Production of ML-236B, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, by Penicillium citrinum: Improvements of strain and culture conditions
    • Hosobuchi M, Shioiri T, Ohyama J, Arai M, Iwado S, Yoshikawa H (1993) Production of ML-236B, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, by Penicillium citrinum: Improvements of strain and culture conditions. Biosci Biotech Biochem 57:1414-1419
    • (1993) Biosci Biotech Biochem , vol.57 , pp. 1414-1419
    • Hosobuchi, M.1    Shioiri, T.2    Ohyama, J.3    Arai, M.4    Iwado, S.5    Yoshikawa, H.6
  • 16
    • 0023788045 scopus 로고
    • Mutational analysis of the GAL4-encoded transcriptional activator protein of Saccharomyces cerevisiae
    • Johnston M, Dover J (1988) Mutational analysis of the GAL4-encoded transcriptional activator protein of Saccharomyces cerevisiae. Genetics 120:63-74
    • (1988) Genetics , vol.120 , pp. 63-74
    • Johnston, M.1    Dover, J.2
  • 17
    • 0028862319 scopus 로고
    • Molecular cloning and sequencing of the hcs gene, which encodes 3-hydroxy-3-methylglutaryl coenzyme A synthase of Schizosaccharomyces pombe
    • Katayama S, Adachi N, Takao K, Nakagawa T, Matsuda H, Kawamukai M (1995) Molecular cloning and sequencing of the hcs gene, which encodes 3-hydroxy-3-methylglutaryl coenzyme A synthase of Schizosaccharomyces pombe. Yeast 11:1533-1537
    • (1995) Yeast , vol.11 , pp. 1533-1537
    • Katayama, S.1    Adachi, N.2    Takao, K.3    Nakagawa, T.4    Matsuda, H.5    Kawamukai, M.6
  • 18
    • 0033591447 scopus 로고    scopus 로고
    • Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis
    • Kennedy J, Auclair K, Kendrew SG, Park C, Vederas JC, Hutchinson CR (1999) Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis. Science 284:1368-1372
    • (1999) Science , vol.284 , pp. 1368-1372
    • Kennedy, J.1    Auclair, K.2    Kendrew, S.G.3    Park, C.4    Vederas, J.C.5    Hutchinson, C.R.6
  • 19
    • 0031915374 scopus 로고    scopus 로고
    • Trichothecene 3-O-acetyl-transferase protects both the producing organism and transformed yeast from related mycotoxins. Cloning and characterization of Tri101
    • Kimura M, Kaneko I, Komiyama M, Takatsuki A, Koshino H, Yoneyama K, Yamaguchi I (1998) Trichothecene 3-O-acetyl-transferase protects both the producing organism and transformed yeast from related mycotoxins. Cloning and characterization of Tri101. J Biol Chem 273:1654-1661
    • (1998) J Biol Chem , vol.273 , pp. 1654-1661
    • Kimura, M.1    Kaneko, I.2    Komiyama, M.3    Takatsuki, A.4    Koshino, H.5    Yoneyama, K.6    Yamaguchi, I.7
  • 20
    • 0033576611 scopus 로고    scopus 로고
    • Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana
    • Lin X, et al (1999) Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Nature 402:761-768
    • (1999) Nature , vol.402 , pp. 761-768
    • Lin, X.1
  • 21
    • 0021916247 scopus 로고
    • Cloning and characterization of the ethanol utilization regulon in Aspergillus nidulans
    • Lockington RA, Sealy-Lewis HM, Scazzocchio C, Davies RW (1985) Cloning and characterization of the ethanol utilization regulon in Aspergillus nidulans. Gene 33:137-149
    • (1985) Gene , vol.33 , pp. 137-149
    • Lockington, R.A.1    Sealy-Lewis, H.M.2    Scazzocchio C.-3    Davies, R.W.4
  • 22
    • 0344348872 scopus 로고    scopus 로고
    • 6 zinc finger transcription factor required for fruiting body development
    • 6 zinc finger transcription factor required for fruiting body development. Genetics 152:191-199
    • (1999) Genetics , vol.152 , pp. 191-199
    • Masloff, S.1    Pöggeler, S.2    Kück, U.3
  • 23
    • 0027526472 scopus 로고
    • Cloning and sequencing of the 3-phosphoglycerate kinase (PGK) gene from Penicillium citrinum and its application to heterologous gene expression
    • Nara F, Watanabe I, Serizawa N (1993a) Cloning and sequencing of the 3-phosphoglycerate kinase (PGK) gene from Penicillium citrinum and its application to heterologous gene expression. Curr Genet 23:134-140
    • (1993) Curr Genet , vol.23 , pp. 134-140
    • Nara, F.1    Watanabe, I.2    Serizawa, N.3
  • 24
    • 0027441520 scopus 로고
    • Development of a transformation system for the filamentous ML-236B (compactin)-producing fungus Penicillium citrinum
    • Nara F, Watanabe I, Serizawa N (1993b) Development of a transformation system for the filamentous ML-236B (compactin)-producing fungus Penicillium citrinum. Curr Genet 23:28-32
    • (1993) Curr Genet , vol.23 , pp. 28-32
    • Nara, F.1    Watanabe, I.2    Serizawa, N.3
  • 25
    • 0025299346 scopus 로고
    • Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7 alpha-hydroxylase
    • Noshiro M, Okuda K (1990) Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7 alpha-hydroxylase. FEBS Lett 268:137-140
    • (1990) FEBS Lett , vol.268 , pp. 137-140
    • Noshiro, M.1    Okuda, K.2
  • 26
    • 0027413467 scopus 로고
    • Aristolochene synthase. Isolation, characterization, and bacterial expression of a sesquiterpenoid biosynthetic gene (Ari1) from Penicillium roqueforti
    • Proctor RH, Hohn TM (1993) Aristolochene synthase. Isolation, characterization, and bacterial expression of a sesquiterpenoid biosynthetic gene (Ari1) from Penicillium roqueforti. J Biol Chem 268:4543-4548
    • (1993) J Biol Chem , vol.268 , pp. 4543-4548
    • Proctor, R.H.1    Hohn, T.M.2
  • 29
    • 0029803121 scopus 로고    scopus 로고
    • 6 zinc cluster family of transcriptional regulators
    • 6 zinc cluster family of transcriptional regulators. Nucleic Acids Res 24:4599-4607
    • (1996) Nucleic Acids Res , vol.24 , pp. 4599-4607
    • Schjerling, P.1    Holmberg, S.2
  • 30
    • 0021030445 scopus 로고
    • Microbial hydroxylation of ML-236B (compactin). Studies on microorganisms capable of 3 beta-hydroxylation of ML-236B
    • Serizawa N, Serizawa S, Nakagawa K, Furuya K, Okazaki T, Terahara A (1983) Microbial hydroxylation of ML-236B (compactin). Studies on microorganisms capable of 3 beta-hydroxylation of ML-236B. J Antibiot 36:887-891
    • (1983) J Antibiot , vol.36 , pp. 887-891
    • Serizawa, N.1    Serizawa, S.2    Nakagawa, K.3    Furuya, K.4    Okazaki, T.5    Terahara, A.6
  • 31
    • 0030953790 scopus 로고    scopus 로고
    • Molecular cloning and expression of amadoriase isoenzyme (fructosyl amine:oxygen oxidoreductase, EC 1.5.3) from Aspergillus fumigatus
    • Takahashi M, Pischetsrieder M, Monnier VM (1997) Molecular cloning and expression of amadoriase isoenzyme (fructosyl amine:oxygen oxidoreductase, EC 1.5.3) from Aspergillus fumigatus. J Biol Chem 272:12505-12507
    • (1997) J Biol Chem , vol.272 , pp. 12505-12507
    • Takahashi, M.1    Pischetsrieder, M.2    Monnier, V.M.3
  • 34
    • 0023707039 scopus 로고
    • Cysteine residues in the zinc finger and amino acids adjacent to the finger are necessary for DNA binding by the LAC9 regulatory protein of Kluyveromyces lactis
    • Witte MM, Dickson RC (1988) Cysteine residues in the zinc finger and amino acids adjacent to the finger are necessary for DNA binding by the LAC9 regulatory protein of Kluyveromyces lactis. Mol Cell Biol 8:3726-3733
    • (1988) Mol Cell Biol , vol.8 , pp. 3726-3733
    • Witte, M.M.1    Dickson, R.C.2
  • 37
    • 0021346063 scopus 로고
    • Transformation of Aspergillus nidulans by using a trpC plasmid
    • Yelton MM, Hamer JE, Timberlake WE (1984) Transformation of Aspergillus nidulans by using a trpC plasmid. Proc Natl Acad Sci USA 81:1470-1474
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 1470-1474
    • Yelton, M.M.1    Hamer, J.E.2    Timberlake, W.E.3
  • 38
    • 0026055102 scopus 로고
    • nit-4, a pathway-specific regulatory gene of Neurospora crassa, encodes a protein with a putative binuclear zinc DNA-binding domain
    • Yuan GF, Fu YH, Marzluf GA (1991) nit-4, a pathway-specific regulatory gene of Neurospora crassa, encodes a protein with a putative binuclear zinc DNA-binding domain. Mol Cell Biol 1:5735-5745
    • (1991) Mol Cell Biol , vol.1 , pp. 5735-5745
    • Yuan, G.F.1    Fu, Y.H.2    Marzluf, G.A.3


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