Expression of the cyclin-kinase inhibitors p21(WAF1) and p27(Kip1) and the p53 tumor suppressor genes in adult-onset laryngeal papillomas

European Archives of Oto-Rhino-Laryngology

Volumn 259, Issue 10, 2002, Pages 516-520

  Erdamar, Burak ^a   Keles, Nesil ^a   Kaur, Ahmet ^b   Suoglu, Yusufhan ^a   Kiyak, Erkan ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b Sitonet Pathology Laboratory   (Turkey)

Author keywords

Larynx; p21(WAF1); p27(Kip1); p53; Papillomas

Indexed keywords

PROTEIN P21; PROTEIN P27; PROTEIN P53;

ADULT; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LARYNX MUCOSA; LARYNX PAPILLOMATOSIS; PATHOGENESIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION;

EID: 0036434399     PISSN: 09374477     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00405-002-0502-x     Document Type: Conference Paper

References (20)

1. Adams V, Schmid S, Zariwala M, Schmid M, Kleihues P, Briner J, Cchafer R (1999) Prevalence of human papilloma virus DNA in head and neck cancers carrying wild-type or mutant p53 tumor suppressor genes. Canc Res 19: 1-6
2. Alani RM, Munger K (1998) Human papilloma virus and associated malignancies. J Clin Oncol 16: 330-337
3. Benjamin B, Parsons D (1998) Recurrent respiratory papillomatosis: A 10-year study. J Larnyngol Otol 102: 1022-1028
4. Cruz IB, Snijders PJF, Meijer CJ, Braakhuis BJ, Snow GB, Waalboomers JM, van Der Waal I (1998) p53 expression above the basal cell layer in oral mucosa in an early event of malignant transformation and with predictive value for developing oral squamous cell carcinoma. J Pathol 184: 360-384
5. (WAF1) and p53 tumor suppressor gene in laryngeal cancer. Clin Otolaryngol 25: 23-27
6. Jones SR, Myers EN, Barnes L (1984) Benign neoplasms of the larynx. Otolaryngol Clin North Am 17: 151-178
7. Kip1 protein in epithelial dysplasia and carcinoma of the oral cavity. Am J Pathol 152: 585-590
8. Lin KY, Westra WH, Kashima HK, Mounts P, Wu TC (1997) Coinfection of HPV-11 and HPV-16 in a case of laryngeal squamous papilloma with severe dysplasia. Laryngoscope 107: 942-947
9. Mirza N, Montone K, Sato Y, Kroger H, Kennedy DW (1998) Identification of p53 and human papilloma virus in Schneiderian papillomas. Laryngoscope 108: 497-500
10. 1WAF1/Cip1 expression is associated with cell differentiation but not with p53 mutations in squamous cell carcinoma of the larynx. J Pathol 183: 156-163
11. Parker SB, Eichele G, Zhang P, Rawls A, Sands AT, Bradley A, Olson EN, Harper JW, Elledge SJ (1995) p53 independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science 267: 1024-1027
12. Philipp J, Gurley KE, Seidel K, Kemp CJ (1998) Tumor suppression by p2Kip1 and p21Cip1 during chemically induced skin carcinogenesis. Oncogene 18: 4689-4698
13. Pruneri G, Pignataro L, Carboni N, Buffa R, Finizio D, Cesena BM, Neri A (1999) Clinical relevance of expression of CIP/KIP cell-cycle inhibitors p21 and p27 in laryngeal cancer. J Clin Oncol 17: 3150-3159
14. Rehberg E, Deterichs G, Kleinsasser O (1998) Malignant transformation of nonirradiated juvenile laryngeal papillomatosis. Eur Arch Otorhinolaryngol 225 [Suppl 1]: S21
15. Satoh M, Hatakeyama S, Sashima M, Suzuki A (1990) Immunohistochemical detection of ras p21 in oral papillomas. J Oral Pathol Med 1990 19: 490-491
16. WAF1 and p53, and human papilloma virus infection in benign and malignant tumors of sinonasal regions. Histopathology 35: 55-64
17. Sheffner M, Werness BA, Huybregtse JM, Levine AJ, Howley PM (1990) The E6 oncoprotein encoded by human papilloma virus type 16 and 18 promotes degradation of p53. Cell 63: 1129-1136
18. Sherr CJ, Roberts JM (1995) Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 9: 1149-1163
19. Uloza V (2000) The course of laryngeal papillomatosis treated by endolaryngeal microsurgery. Eur Arch Otorhinolaryngol 257: 498-501
20. Yoder MG, Batsakis JG (1980) Squamous cell carcinoma in solitary laryngeal papillomas. Otolaryngol Head Neck Surg 88: 745-748