Noradrenaline release in rat locus coeruleus is regulated by both opioid and α2-adrenoceptors

Pharmacological Research

Volumn 45, Issue 5, 2002, Pages 407-412

  Nakai, Tohru ^a   Hayashi, Masahiro ^a   Ichihara, Kazuo ^a   Wakabayashi, Hiroyuki ^b   Hoshi, Katsuji ^a  

^a HOKKAIDO INSTITUTE OF TECHNOLOGY   (Japan)

^b NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

Author keywords

Locus coeruleus; Microdialysis; Morphine; Noradrenaline; Yohimbine; 2 adrenoceptors

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; NALOXONE; NORADRENALIN; OPIATE RECEPTOR; YOHIMBINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG WITHDRAWAL; EXTRACELLULAR FLUID; LOCUS CERULEUS; MALE; MORPHINE ADDICTION; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; WITHDRAWAL SYNDROME;

EID: 0036422190     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.2002.0962     Document Type: Article

References (33)

1. Rasmussen K. The role of the locus coeruleus and N-methyl-D-aspartic acid (NMDA) and AMPA receptors in opiate withdrawal. Neuropsychopharmacol 1995; 13: 295-300.
2. Ho IK, Feng YZ, Tokuyama S, Hoshi K, Rockhold RW. Glutamate in opioid dependence. Rev Jpn J Psychopharmacol 1997; 17: 175-80.
3. Hoshi K, Yamamoto A, Ishizuki S, Fujihira E, Ichihara K. Excitatory amino acid release in the locus coeruleus during naloxone-precipitated morphine withdrawal in adjuvant arthritic rats. Inflamm Res 2000; 49: 036-041.
4. Atweh SF, Kuhar MJ. Autoradiographic localization of opiate receptors in rat brain. II. The brain stem. Brain Res 1977; 129: 1-12.
5. Foote SL, Bloom FE, Astone-Jones G. Nucleus locus coeruleus: New evidence of anatomical and physiological specificity. Physiol Rev 1983; 63: 844-914.
6. Tempel A, Zukin RS. Neuroanatomical patterns of the μ, δ, and κ opioid receptors of rat brain as determined by quantitative in vitro autoradiography. Proc Natl Acad Sci USA 1987; 84: 4308-12.
7. Aghajanian GK. Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine. Nature 1978; 276: 186-8.
8. Crawley JN, Hattox SE, Maas JW, Roth RH. 3-methoxy-4-hydroxyphenethylene-glycol increase in plasma after stimulation of the nucleus locus coeruleus. Brain Res 1978; 141: 380-4.
9. Zhu H, Rockhold RW, Ho IK. The role of glutamate in physical dependence on opioids. Rev Jpn J Pharmacol 1998; 76: 1-14.
10. Done C, Silverstone P, Sharp T. Effect of naloxone-precipitated morphine withdrawal on noradrenaline release in rat hippocampus in vivo. Eur J Pharmacol 1992; 215: 333-6.
11. Feng YZ, Rockhold RW, Ho IK. Nor-binaltorphimine precipitates withdrawal and excitatory amino acid release in the locus coeruleus of butorphanol- but not morphine-dependent rats. J Pharmacol Exp Ther 1997; 283: 932-8.
12. Kaehler ST, Sinner C, Chatterjee SS, Philippu A. Hyperforin enhances the extracellular concentrations of catecholamines, serotonin and glutamate in the rat locus coeruleus. Neurosci Lett 1999; 262: 199-202.
13. Gold MS, Pottash AC, Sweeney DR, Kleber HD. Opiate withdrawal using clonidine. J Am Med Assoc 1980; 243: 343-46.
14. Redmond DE Jr, Krystal JH. Multiple mechanisms of withdrawal from opioid drugs. Annu Rev Neurosci 1984; 7: 443-78.
15. Rosario LA, Abercrombie ED. Individual differences in behavioral reactivity: Correlation with stress-induced norepinephrine efflux in the ippocampus of Sprague-Dawley rats. Brain Res Bull 1999; 48: 595-602.
16. Aghajanian GK, Kogan JH, Moghaddam B. Opiate withdrawal increases glutamate and aspartate efflux in the locus coeruleus: An in vivo microdialysis study. Brain Res 1994; 636: 126-30.
17. Distefano PS, Brown OL. Biochemical correlates of morphine withdrawal. 2. Effects of clonidine. J Pharmacol Exp Ther 1985; 233: 339-44.
18. Charney DS, Heninger GR, Breier A. Noradrenergic function in panic anxiety. Effects of yohimbine in healthy subjects and patients with agoraphobia and panicdisorder. Arch Gen Psychiatry 1984; 41: 751-63.
19. Drijfhout WJ, Van der Linde AG, Kooi SE, Grol CJ, Westerink BHC. Norepinephrine release in the rat pineal gland: The input from the biological clock measured by in vivo microdialysis. J Neurochem 1996; 66: 748-55.
20. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates, 2nd Edn. Orlando, FL: Academic Press Inc, 1986.
21. Hoshi K, Ma T, Oh S, Ho IK. Increased release of excitatory amino acids in rat locus coeruleus in μ-opioid agonist dependent rats precipitated by nor-binaltorphimine. Brain Res 1997; 753: 63-8.
22. Akaoka H, Aston-Jones G. Opiate withdrawal-induced hyperactivity of locus coeruleus neurons is substantially mediated by augmented excitatory amino acid input. J Neurosci 1991; 11: 3830-9.
23. Aston-Jones G, Hirata H, Akaoka H. Local opiate withdrawal in locus coeruleus in vivo. Brain Res 1997; 765: 331-6.
24. 2 adrenoceptor mechanisms. Br J Anaesth 1995; 74: 73-8.
25. Crowder JM, Norris DK, Bradford HF. Morphine inhibition of calcium fluxes, neurotransmitter release and protein and lipid phosphorylation in brain slices and synaptosomes. Biochem Pharmacol 1986; 35: 2501-7.
26. Olsson Y, Sharma HS, Nyberg F, Westman J. In: The opioid receptor antagonist naloxone influences the pathophysiology of spinal cord injury. vol. 104, Nyberg F, Sharma HS, Wiesenfeld-Hallin Z, eds. B.V. Amsterdam, Netherlands: Elsevier Science, 1995: 381-99.
27. 2-adrenoceptors on SH-SY5Y human neuroblastoma cells. Eur J Pharmacol 1992; 227: 19-24.
28. Christie MJ. Mechanisms of opioid actions on neurones of the locus coeruleus. Prog Brain Res 1992; 88: 197-205.
29. Noble F, Cox BM. The role of dopaminergic systems in opioid receptor desensitization in nucleus accumbens and caudate putamen of rat after chronic orphine treatment. J Pharmacol Exp Ther 1997; 283: 557-65.
30. Harris GC, Williams JT. Transient homologous μ-opioid receptor desensitisation in rat locus coeruleus neurons. J Neurosci 1991; 11: 2574-81.
31. Pineda J, Ruiz-Ortega JA, Ugedo L. Receptor reserve and turnover of alpha-2 adrenoceptors that mediate the clonidine-induced inhibition of rat locus coeruleus neurons in vivo. J Pharmacol Exp Ther 1997; 281: 690-8.
32. Kamisaki Y, Hamahashi T, Hamada T, Maeda K, Itoh T. Presynaptic inhibition by clonidine of neurotransmitter amino acid release in various brain regions. Eur J Pharmacol 1992; 217: 57-63.
33. Dossin O, Hanoun N, Zajac J-M. Involvement of locus coeruleus projections in opiate withdrawal but not in opiate tolerance in mice. Eur J Pharmacol 1996; 308: 271-4.