Involvement of locus coeruleus projections in opiate withdrawal but not in opiate tolerance in mice

European Journal of Pharmacology

Volumn 308, Issue 3, 1996, Pages 271-274

  Dossin, Olivier ^a   Hanoun, Naïma ^a   Zajac, Jean Marie ^a  

^a CNRS   (France)

Author keywords

DSP 4 (N (2 chloromethyl) N ethyl 2 bromobenzylamine); Locus coeruleus; Mouse; Opiate; Tolerance; Withdrawal

Indexed keywords

2 BROMO N (2 CHLOROETHYL) N ETHYLBENZYLAMINE; DOPAMINE; MORPHINE; NALOXONE; NEUROTOXIN; NORADRENALIN;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATECHOLAMINE BRAIN LEVEL; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; JUMPING; LOCUS CERULEUS; MALE; MORPHINE ADDICTION; MORPHINE TOLERANCE; MOUSE; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; TAIL FLICK TEST; WITHDRAWAL SYNDROME;

EID: 0030601255     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00318-4     Document Type: Article

References (15)

1. Aghajanian, G.K., 1978, Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal syndrome by clonidine, Nature 276, 186.
2. Akoaka, H. and G. Aston-Jones, 1991, Opiate withdrawal-induced hyperactivity of locus coeruleus neurons is substantially mediated by augmented excitatory amino-acid imput, J. Neurosci. 11, 3830.
3. Atgie, C., M. Nibbelink and L. Ambid, 1990, Sympathoadrenal activity and hypoglycemia in the hibernating garden dormouse, Physiol. Behav. 48, 783.
4. Britton, K.T., T. Svensson, J. Schwanz, F.E. Bloom and G.F. Koob, 1984, Dorsal noradrenergic bundle lesions fail to alter opiate withdrawal or suppression of opiate withdrawal by clonidine, Life Sci. 34, 133.
5. Chieng, B. and M.J. Christie, 1995, Lesions to terminal of noradrenergic locus coeruleus neurones do not inhibit opiate withdrawal behaviour in rats, Neurosci. Lett. 186, 37.
6. Fritschy, J.-M. and R. Grzanna, 1989, Immunohistochemical analysis of the neurotoxic effect of DSP-4 identifies two populations of noradrenergic axons terminals. Neuroscience 30, 181.
7. Fritschy, J.-M., M. Geffard and R. Grzanna, 1990, The response of noradrenergic axons to systemically administered DSP-4 in the rat: an immunohistochemical study using antibodies to noradrenaline and dopamine-β-hydroxylase, J. Chem. Neuroanat. 3, 309.
8. Funada, M., T. Suzuki, Y. Sugano, M. Tsubai, M. Misawa, H. Ueda and Y. Misu, 1994, Role of β-adrenoreceptors in the expression of morphine withdrawal signs, Life Sci. 54, 113.
9. Kaneto, H. and M. Inoue, 1990, Action site of adrenergic blockers to suppress the development of tolerance to morphine analgesia, Brain Res. 507, 35.
10. Kogan, J.H., E.J. Nestler and G.K. Aghajanian, 1992, Elevated basal firing rates and enhanced responses to 8-Br-cAMP in locus coeruleus neurons in brain slices from opiate-dependent rats, Eur. J. Pharmacol. 211, 47.
11. Maldonaldo, R. and G.F. Koob, 1993, Destruction of the locus coeruleus decreases physical signs of opiate withdrawal, Brain Res. 605, 128.
12. Maldonaldo, R., L. Stinus, L.H. Gold and G.F. Koob, 1992, Role of different brain structures in the expression of the physical morphine withdrawal syndrome, J. Pharmacol. Exp. Ther. 261, 669.
13. Olpe, H.R., J. Laszlo, D.J. Dooley, J. Heid and M.W. Steinmann, 1983, Decreased activity of locus coeruleus neurons in the rat after DSP-4 treatment, Neurosci. Lett. 40, 81.
14. Rasmussen, K., D.B. Beitner-Johnson, J.H. Krystal, G.K. Aghajanian and E.J. Nestler, 1990, Opiate withdrawal and the rat locus coeruleus: behavioral, electrophysiological and biochemical correlates, J. Neurosci. 10, 2308.
15. Taylor, J.R., J.D. Elsworth, E.J. Garcia, S.J. Grant, R.H. Roth and D.E. Redmond, 1988, Clonidine infusions into the locus coeruleus attenuate behavioral and neurochemical changes associated with naloxoneprecipitated withdrawal, Psychopharmacology 96, 121.