메뉴 건너뛰기




Volumn 281, Issue 2, 1997, Pages 690-698

Receptor reserve and turnover of alpha-2 adrenoceptors that mediate the clonidine-induced inhibition of rat locus coeruleus neurons in vivo

Author keywords

[No Author keywords available]

Indexed keywords

2 ETHOXY 1(2H) QUINOLINECARBOXYLIC ACID ETHYL ESTER; ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE;

EID: 0030954423     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (27)

References (54)
  • 1
    • 0022414001 scopus 로고
    • 2-adrenoceptor binding and function after irreversible inactivation by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)
    • 2-adrenoceptor binding and function after irreversible inactivation by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ). Eur. J. Pharmacol. 116: 175-178, 1985.
    • (1985) Eur. J. Pharmacol. , vol.116 , pp. 175-178
    • Adler, C.H.1    Meller, E.2    Goldstein, M.3
  • 2
    • 0023153667 scopus 로고
    • Receptor reserve at the alpha-2 adrenergic receptor in the rat cerebral cortex
    • ADLER, C. H., MELLER, E. AND GOLDSTEIN, M.: Receptor reserve at the alpha-2 adrenergic receptor in the rat cerebral cortex. J. Pharmacol. Exp. Ther. 240: 508-515, 1987.
    • (1987) J. Pharmacol. Exp. Ther. , vol.240 , pp. 508-515
    • Adler, C.H.1    Meller, E.2    Goldstein, M.3
  • 3
    • 0027530780 scopus 로고
    • 2-autoreceptors: Agonist dissociation constants and recovery after irreversible inactivation
    • 2-autoreceptors: Agonist dissociation constants and recovery after irreversible inactivation. Br. J. Pharmacol. 108: 370-375, 1993.
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 370-375
    • Agneter, E.1    Drobny, H.2    Singer, E.A.3
  • 4
    • 0026532290 scopus 로고
    • Combining in vivo volume-controlled pressure microejection with extracellular unit recording
    • AKAOKA, H., SAUNIER, C. -F., CHERGUI, K., CHARLÉTY, P., BUDA, M. AND CHOUVET, G.: Combining in vivo volume-controlled pressure microejection with extracellular unit recording. J Neurosci. Methods 42: 119-128, 1992.
    • (1992) J Neurosci. Methods , vol.42 , pp. 119-128
    • Akaoka, H.1    Saunier, C.F.2    Chergui, K.3    Charléty, P.4    Buda, M.5    Chouvet, G.6
  • 5
    • 0026920269 scopus 로고
    • 2-adrenergic receptors exerting opposing effects on cAMP production
    • 2-adrenergic receptors exerting opposing effects on cAMP production. Receptor 2: 195-206, 1992.
    • (1992) Receptor , vol.2 , pp. 195-206
    • Atkinson, B.N.1    Minneman, K.P.2
  • 7
    • 0014435890 scopus 로고
    • N-carboxylic acid esters of 1,2- and 1,4-dihydroquinolines. A new class of irreversible inactivators of the catecholamine receptors and potent central nervous system depressants
    • BELLEAU, B., MARTEL, R., LACASSE, G., MÉNARD, M., WEINBERG, N. L. AND PERRON, Y. G.: N-carboxylic acid esters of 1,2- and 1,4-dihydroquinolines. A new class of irreversible inactivators of the catecholamine receptors and potent central nervous system depressants. J. Am. Chem. Soc. 90: 823-824, 1968.
    • (1968) J. Am. Chem. Soc. , vol.90 , pp. 823-824
    • Belleau, B.1    Martel, R.2    Lacasse, G.3    Ménard, M.4    Weinberg, N.L.5    Perron, Y.G.6
  • 8
    • 0021058380 scopus 로고
    • Operational models of pharmacological agonism
    • BLACK, J. W. AND LEFF, P.: Operational models of pharmacological agonism. Proc. R. Soc. Lond. 220: 141-162, 1983.
    • (1983) Proc. R. Soc. Lond. , vol.220 , pp. 141-162
    • Black, J.W.1    Leff, P.2
  • 9
    • 0017164341 scopus 로고
    • Noradrenergic neurones of the locus coeruleus: Inhibition by epinephrine and activation by the alpha antagonist piperoxane
    • CEDARBAUM, J. M. AND AGHAJANIAN, G. K.: Noradrenergic neurones of the locus coeruleus: inhibition by epinephrine and activation by the alpha antagonist piperoxane. Brain. Res. 112: 413-419, 1976.
    • (1976) Brain. Res. , vol.112 , pp. 413-419
    • Cedarbaum, J.M.1    Aghajanian, G.K.2
  • 10
    • 0017741055 scopus 로고
    • Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization
    • CEDARBAUM, J. M. AND AGHAJANIAN, G. K.: Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization. Eur. J. Pharmacol. 44: 375-385, 1977.
    • (1977) Eur. J. Pharmacol. , vol.44 , pp. 375-385
    • Cedarbaum, J.M.1    Aghajanian, G.K.2
  • 12
    • 0024570187 scopus 로고
    • Differences in dopamine receptor reserve for N-n-propylnorapomorphine enantiomers: Single unit recording studies after partial inactivation of receptor by EEDQ
    • COX, R. F. AND WASZCZAK, B. L.: Differences in dopamine receptor reserve for N-n-propylnorapomorphine enantiomers: single unit recording studies after partial inactivation of receptor by EEDQ. Mol. Pharmacol 34: 125-131, 1989.
    • (1989) Mol. Pharmacol , vol.34 , pp. 125-131
    • Cox, R.F.1    Waszczak, B.L.2
  • 14
    • 0025896714 scopus 로고
    • 2-adrenoceptor agonists on locus coeruleus firing rate and brain noradrenaline turnover in N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)-treated rats
    • 2-adrenoceptor agonists on locus coeruleus firing rate and brain noradrenaline turnover in N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)-treated rats. Naunyn-Schmiedeberg Arch. Pharmacol. 343: 472-477, 1991.
    • (1991) Naunyn-Schmiedeberg Arch. Pharmacol. , vol.343 , pp. 472-477
    • Engberg, G.1    Eriksson, E.2
  • 15
    • 84981848149 scopus 로고
    • Comparison of dissociation constants and of relative efficacies of selected agonists acting on parasympathetic receptors
    • FURCHGOTT, R. F. AND BURSZTYN, P.: Comparison of dissociation constants and of relative efficacies of selected agonists acting on parasympathetic receptors. Ann. N.Y. Acad. Sci. 144: 882-899, 1967.
    • (1967) Ann. N.Y. Acad. Sci. , vol.144 , pp. 882-899
    • Furchgott, R.F.1    Bursztyn, P.2
  • 16
    • 0002355204 scopus 로고
    • The use of beta-haloalkylamines in the differentiation of receptors and in the determination of dissociation constants of receptor-agonist complexes
    • FURCHGOTT, R. F.: The use of beta-haloalkylamines in the differentiation of receptors and in the determination of dissociation constants of receptor-agonist complexes. Adv. Drug Res. 3: 21-55, 1966.
    • (1966) Adv. Drug Res. , vol.3 , pp. 21-55
    • Furchgott, R.F.1
  • 17
    • 0026356256 scopus 로고
    • Ability of SK&F 104078 and SK&F 104856 to identify alpha-2 adrenoceptor subtypes in NCB20 cells and guinea pig lung
    • GLEASON, M. M. AND HIEBLE, J. P.: Ability of SK&F 104078 and SK&F 104856 to identify alpha-2 adrenoceptor subtypes in NCB20 cells and guinea pig lung. J. Pharmacol. Exp. Ther. 259: 1124-1132, 1991.
    • (1991) J. Pharmacol. Exp. Ther. , vol.259 , pp. 1124-1132
    • Gleason, M.M.1    Hieble, J.P.2
  • 18
    • 0023910816 scopus 로고
    • Clonidine regularizes substantia nigra dopamine cell firing
    • GRENHOFF, J. AND SVENSSON, T. H.: Clonidine regularizes substantia nigra dopamine cell firing. Life Sci. 42: 2003-2009, 1988.
    • (1988) Life Sci. , vol.42 , pp. 2003-2009
    • Grenhoff, J.1    Svensson, T.H.2
  • 19
    • 0021971236 scopus 로고
    • The effects of phenoxybenzamine on specific binding and function of central α-adrenoceptors in the rabbit
    • HAMILTON, C. A. AND REID, J. L.: The effects of phenoxybenzamine on specific binding and function of central α-adrenoceptors in the rabbit. Brain Res. 344: 89-95, 1985.
    • (1985) Brain Res. , vol.344 , pp. 89-95
    • Hamilton, C.A.1    Reid, J.L.2
  • 20
    • 0024580363 scopus 로고
    • A new method for estimation of agonist dissociation constants (Ka): Directly fitting the postinactivation concentration-response curve to a nested hyperbolic equation
    • JAMES, M. K., MORGAN, P. H. AND LEIGHTON, H. J.: A new method for estimation of agonist dissociation constants (Ka): directly fitting the postinactivation concentration-response curve to a nested hyperbolic equation. J. Pharmacol. Exp. Ther. 249: 61-69, 1989.
    • (1989) J. Pharmacol. Exp. Ther. , vol.249 , pp. 61-69
    • James, M.K.1    Morgan, P.H.2    Leighton, H.J.3
  • 22
    • 0025663017 scopus 로고
    • Drugs and receptors. An overview of the current state of knowledge
    • KENAKIN, T.: Drugs and receptors. An overview of the current state of knowledge. Drugs 40: 666-687, 1990.
    • (1990) Drugs , vol.40 , pp. 666-687
    • Kenakin, T.1
  • 23
    • 0025818105 scopus 로고
    • Effects of long-term desipramine administration on noradrenergic neurotransmission: Electrophysiological studies in the rat brain
    • LACROIX, D., BLIER, P., CURET, O. AND DE MONTIGNY, C.: Effects of long-term desipramine administration on noradrenergic neurotransmission: electrophysiological studies in the rat brain. J. Pharmacol. Exp. Ther. 257: 1081-1090, 1991.
    • (1991) J. Pharmacol. Exp. Ther. , vol.257 , pp. 1081-1090
    • Lacroix, D.1    Blier, P.2    Curet, O.3    De Montigny, C.4
  • 24
    • 0025205262 scopus 로고
    • Using linear and non-linear regression to fit biochemical data
    • LEATHERBARROW, R. J.: Using linear and non-linear regression to fit biochemical data. Trends Biochem. Sci. 15: 455-458, 1990.
    • (1990) Trends Biochem. Sci. , vol.15 , pp. 455-458
    • Leatherbarrow, R.J.1
  • 25
    • 0025141367 scopus 로고
    • Errors in agonist affinity estimation: Do they and should they occur in isolated tissue experiments?
    • LEFF, P., DOUGALL, I. G., HARPER, D. H. AND DAINTY, I. A.: Errors in agonist affinity estimation: do they and should they occur in isolated tissue experiments?. Trends Pharmacol. Sci. 11: 64-67, 1990.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 64-67
    • Leff, P.1    Dougall, I.G.2    Harper, D.H.3    Dainty, I.A.4
  • 26
    • 0021747813 scopus 로고
    • 2-adrenoceptors in locus coeruleus neurons
    • 2-adrenoceptors in locus coeruleus neurons. Brain Res. 321: 180-182, 1984.
    • (1984) Brain Res. , vol.321 , pp. 180-182
    • Levln, B.E.1
  • 27
    • 0024013229 scopus 로고
    • Continuous variation of agonist affinity constants
    • MACKAY, D.: Continuous variation of agonist affinity constants. Trends Pharmacol. Sci. 9: 156-157, 1988b.
    • (1988) Trends Pharmacol. Sci. , vol.9 , pp. 156-157
    • Mackay, D.1
  • 28
    • 0023940958 scopus 로고
    • Concentration-response curves and receptor classification: Null method or operational model?
    • MACKAY, D.: Concentration-response curves and receptor classification: null method or operational model?. Trends Pharmacol. Sci. 9: 202-205, 1988a.
    • (1988) Trends Pharmacol. Sci. , vol.9 , pp. 202-205
    • Mackay, D.1
  • 29
    • 0023160830 scopus 로고
    • Metabolism of alpha- and beta-adrenergic receptors in vitro and in vivo
    • MAHAN, L. C., MCKERNAN, M. AND INSEL, P. A.: Metabolism of alpha- and beta-adrenergic receptors in vitro and in vivo. Ann. Rev. Pharmacol. Toxicol. 27: 215-235, 1987.
    • (1987) Ann. Rev. Pharmacol. Toxicol. , vol.27 , pp. 215-235
    • Mahan, L.C.1    Mckernan, M.2    Insel, P.A.3
  • 30
    • 0019971988 scopus 로고
    • Relative potencies of alpha-1 and alpha-2 antagonists in the locus ceruleus, dorsal raphe and dorsal lateral geniculate nuclei: An electrophysiological study
    • MARWAHA, J. AND AGHAJANIAN, G. K.: Relative potencies of alpha-1 and alpha-2 antagonists in the locus ceruleus, dorsal raphe and dorsal lateral geniculate nuclei: an electrophysiological study. J. Pharmacol. Exp. Ther. 222: 287-293, 1982.
    • (1982) J. Pharmacol. Exp. Ther. , vol.222 , pp. 287-293
    • Marwaha, J.1    Aghajanian, G.K.2
  • 32
    • 0021893269 scopus 로고
    • 2 dopamine receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vivo: Selective protection by neuroleptics
    • 2 dopamine receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vivo: Selective protection by neuroleptics. J. Pharmacol. Exp. Ther. 233: 656-662, 1985.
    • (1985) J. Pharmacol. Exp. Ther. , vol.233 , pp. 656-662
    • Meller, E.1    Bohmaker, K.2    Goldstein, M.3    Friedhoff, A.J.4
  • 33
    • 0023265884 scopus 로고
    • Relationship between receptor occupancy and response at striatal dopamine autoreceptors
    • MELLER, E., BOHMAKER, K., NAMBA, Y., FRIEDHOFF, A. J. AND GOLDSTEIN, M.: Relationship between receptor occupancy and response at striatal dopamine autoreceptors. Mol. Pharmacol. 31: 592-598, 1987.
    • (1987) Mol. Pharmacol. , vol.31 , pp. 592-598
    • Meller, E.1    Bohmaker, K.2    Namba, Y.3    Friedhoff, A.J.4    Goldstein, M.5
  • 35
    • 0024197489 scopus 로고
    • N-ethoxycarbonyl-2-ethoxyl-1,2-dihydroquinoline (EEDQ): A new tool to probe CNS receptor function
    • MELLER, E., GOLDSTEIN, M., FRIEDHOFF, A. J. AND SCHWEITZER, J. W.: N-ethoxycarbonyl-2-ethoxyl-1,2-dihydroquinoline (EEDQ): A new tool to probe CNS receptor function. Adv. Exp. Med. Biol. 235: 121-136, 1988.
    • (1988) Adv. Exp. Med. Biol. , vol.235 , pp. 121-136
    • Meller, E.1    Goldstein, M.2    Friedhoff, A.J.3    Schweitzer, J.W.4
  • 36
    • 8244226631 scopus 로고
    • 2-adrenoceptors mediating mydriasis in the rat
    • Adrenoceptors: Structure, Mechanisms, Function. ed. by E. Szabadi and C. M. Bradshaw, Birkhäuser Verlag, Basel, Switzerland
    • 2-adrenoceptors mediating mydriasis in the rat. In Adrenoceptors: Structure, Mechanisms, Function. Advances in Pharmacological Science, ed. by E. Szabadi and C. M. Bradshaw, pp. 335-336, Birkhäuser Verlag, Basel, Switzerland, 1991.
    • (1991) Advances in Pharmacological Science , pp. 335-336
    • Menargues, A.1    Obach, R.2    García-Sevilla, J.A.3
  • 38
    • 0023442604 scopus 로고
    • Fitting curves to data using nonlinear regression: A practical and nonmathematical review
    • MOTULSKY, H. J. AND RANSNAS, L. A.: Fitting curves to data using nonlinear regression: a practical and nonmathematical review. FASEB J. 1: 365-374, 1987.
    • (1987) FASEB J , vol.1 , pp. 365-374
    • Motulsky, H.J.1    Ransnas, L.A.2
  • 39
    • 0026494695 scopus 로고
    • Decreased sensory responsiveness of noradrenergic neurons in the rat locus coeruleus following phencyclidine or dizocilpine (MK-801): Role of NMDA antagonism
    • MURASE, S., NISELL, M., GRENHOFF, J. AND SVENSSON, T. H.: Decreased sensory responsiveness of noradrenergic neurons in the rat locus coeruleus following phencyclidine or dizocilpine (MK-801): Role of NMDA antagonism. Psychopharmacology 109: 271-276, 1992.
    • (1992) Psychopharmacology , vol.109 , pp. 271-276
    • Murase, S.1    Nisell, M.2    Grenhoff, J.3    Svensson, T.H.4
  • 40
    • 0030201051 scopus 로고    scopus 로고
    • The distribution and significance of CNS adrenoceptors examined with in situ hybridization
    • NICHOLAS, A. P., HÖKFELT, T. AND PIERIBONE, V. A.: The distribution and significance of CNS adrenoceptors examined with in situ hybridization. Trends Pharmacol. Sci. 17: 245-255, 1996.
    • (1996) Trends Pharmacol. Sci. , vol.17 , pp. 245-255
    • Nicholas, A.P.1    Hökfelt, T.2    Pieribone, V.A.3
  • 41
    • 0015049463 scopus 로고
    • Pharmacological estimation of drug-receptor dissociation constants. Statistical evaluation. I. Agonists
    • PARKER, R. B. AND WAUD, D. R.: Pharmacological estimation of drug-receptor dissociation constants. Statistical evaluation. I. Agonists. J. Pharmacol. Exp. Ther. 177: 1-12, 1971.
    • (1971) J. Pharmacol. Exp. Ther. , vol.177 , pp. 1-12
    • Parker, R.B.1    Waud, D.R.2
  • 44
    • 0024379092 scopus 로고
    • An in vivo procedure for the selective inactivation of rat brain cerebral cortical α-adrenoceptors using N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)
    • PILC, A., VETULANI, J., NOMURA, S. AND ENNA, S. J.: An in vivo procedure for the selective inactivation of rat brain cerebral cortical α-adrenoceptors using N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ). Brain Res. 493: 8-13, 1989.
    • (1989) Brain Res. , vol.493 , pp. 8-13
    • Pilc, A.1    Vetulani, J.2    Nomura, S.3    Enna, S.J.4
  • 45
    • 0027327458 scopus 로고
    • Stimulatory effects of clonidine, cirazoline and rilmenidine on locus coeruleus noradrenergic neurones: Possible involvement of imidazoline-preferring receptors
    • PINEDA, J., UGEDO, L. AND GARCÍA-SEVILLA, J. A.: Stimulatory effects of clonidine, cirazoline and rilmenidine on locus coeruleus noradrenergic neurones: Possible involvement of imidazoline-preferring receptors. Naunyn-Schmiedeberg Arch. Pharmacol. 348: 134-140, 1993.
    • (1993) Naunyn-Schmiedeberg Arch. Pharmacol. , vol.348 , pp. 134-140
    • Pineda, J.1    Ugedo, L.2    García-Sevilla, J.A.3
  • 46
    • 8244241729 scopus 로고
    • Pharmacological characterization of the alpha-2 adrenoceptor subtype that modulates the activity of locus coeruleus noradrenergic neurons in rat. 16th Annual Meeting of the European Neuroscience Association
    • RUIZ-ORTEGA, J. A. AND UGEDO, L.: Pharmacological characterization of the alpha-2 adrenoceptor subtype that modulates the activity of locus coeruleus noradrenergic neurons in rat. 16th Annual Meeting of the European Neuroscience Association. Supp. 6 to Eur. J. Neurosci., 1993.
    • (1993) Eur. J. Neurosci. , Issue.6 SUPPL.
    • Ruiz-Ortega, J.A.1    Ugedo, L.2
  • 49
    • 0010673662 scopus 로고
    • A modification of receptor theory
    • STEPHENSON, R. P.; A modification of receptor theory. Br. J. Pharmacol. 11: 379-393, 1956.
    • (1956) Br. J. Pharmacol. , vol.11 , pp. 379-393
    • Stephenson, R.P.1
  • 50
    • 0016593641 scopus 로고
    • Inhibition of both noradrenergic and serotonergic neurones in the brain by the α-adrenergic agonist clonidine
    • SVENSSON, T. H., BUNNEY, B. S. AND AGHAJANIAN, G. K.: Inhibition of both noradrenergic and serotonergic neurones in the brain by the α-adrenergic agonist clonidine. Brain Res. 92: 291-306, 1975.
    • (1975) Brain Res. , vol.92 , pp. 291-306
    • Svensson, T.H.1    Bunney, B.S.2    Aghajanian, G.K.3
  • 51
    • 0021270877 scopus 로고
    • Quantification relationships between α-adrenergic activity and binding affinity of α-adrenoceptor agonists and antagonists
    • TIMMERMANS, P. B. M. W. M., DE JONGE, A., THOOLEN, M. J. M. C., WILFFERT, B., BATINK, H. AND VAN ZWIETEN, P. A.: Quantification relationships between α-adrenergic activity and binding affinity of α-adrenoceptor agonists and antagonists. J. Med. Chem. 27: 495-503, 1984.
    • (1984) J. Med. Chem. , vol.27 , pp. 495-503
    • Timmermans, P.B.M.W.M.1    De Jonge, A.2    Thoolen, M.J.M.C.3    Wilffert, B.4    Batink, H.5    Van Zwieten, P.A.6
  • 53
    • 0014599320 scopus 로고
    • On the measurement of the affinity of partial agonists for receptors
    • WAUD, D. R.: On the measurement of the affinity of partial agonists for receptors. J. Pharmacol. Exp. Ther. 170: 117-122, 1969.
    • (1969) J. Pharmacol. Exp. Ther. , vol.170 , pp. 117-122
    • Waud, D.R.1
  • 54
    • 0021923603 scopus 로고
    • 2 adrenoceptors which increase potassium conductance in rat locus coeruleus
    • 2 adrenoceptors which increase potassium conductance in rat locus coeruleus. Neuroscience 14: 95-101, 1985.
    • (1985) Neuroscience , vol.14 , pp. 95-101
    • Williams, J.T.1    Henderson, G.2    North, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.