Applications of transcranial magnetic stimulation in movement disorders

Journal of Clinical Neurophysiology

Volumn 19, Issue 4, 2002, Pages 272-293

  Cantello, Roberto ^a  

^a MAGGIORE DELLA CARITÀ HOSPITAL   (Italy)

Author keywords

Diagnosis; Movement disorders; Pathophysiology; Transcranial magnetic stimulation; Treatment

Indexed keywords

AMPLITUDE MODULATION; ATAXIA; BRAIN FUNCTION; CLINICAL RESEARCH; CORTICOBASAL DEGENERATION; DIAGNOSTIC VALUE; DYSTONIA; ESSENTIAL TREMOR; EVOKED MUSCLE RESPONSE; GILLES DE LA TOURETTE SYNDROME; HUMAN; HUNTINGTON CHOREA; MOTOR DYSFUNCTION; MOTOR NERVE CONDUCTION; MYOCLONUS; NONHUMAN; PARKINSON DISEASE; PATHOPHYSIOLOGY; PROGRESSIVE SUPRANUCLEAR PALSY; REACTION TIME; REPRODUCIBILITY; RESTLESS LEGS SYNDROME; RETT SYNDROME; REVIEW; SAFETY; SHY DRAGER SYNDROME; STIFF MAN SYNDROME; TRANSCRANIAL MAGNETIC STIMULATION; WILSON DISEASE;

EID: 0036421769     PISSN: 07360258     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004691-200208000-00003     Document Type: Review

References (155)

1. Abbruzzese G, Buccolieri A, Marchese R, Trompetto C, Mandich P, Schieppati M. Intracortical inhibition and facilitation are abnormal in Huntington's disease: A paired magnetic stimulation study. Neurosci Lett 1998;228:87-90.
2. Abbruzzese G, Marchese R, Buccolieri A, Gasparetto B, Trompetto C. Abnormalities of sensorimotor integration in focal dystonia: A transcranial magnetic stimulation study. Brain 2001;124:537-45.
3. Abbruzzese G, Marchese R, Trompetto C. Motor cortical excitability in Huntington's disease. J Neurol Neurosurg Psychiatry 2000;68:120-1.
4. Abbruzzese G, Marchese R, Trompetto C. Sensory and motor evoked potentials in multiple system atrophy: A comparative study with Parkinson's disease. Mov Disord 1997;12:315-21.
5. Abele M, Schulz JB, Burk K, Topka H, Dichgans J, Klockgether T. Evoked potentials in multiple system atrophy. Acta Neurol Scand 2000;101:111-5.
6. Amadio S, Panizza M, Pisano F, et al. Transcranial magnetic stimulation and silent period in spasmodic torticollis. Am J Phys Med Rehabil 2000;79:361-8.
7. Barker AT, Jalinous R, Freeston IL. Non-invasive magnetic stimulation of human motor cortex. Lancet 1985;i:1106-7.
8. Berardelli A. Transcranial magnetic stimulation in movement disorders. In: Paulus W, Hallett M, Rossini PM, Rothwell JC, eds. Transcranial magnetic stimulation. Clin Neurophysiol 1999a;(Suppl. 51):276-80.
9. Berardelli A, Inghilleri M, Priori A, et al. Involvement of corticospinal tracts in Wilson's disease. Mov Disord 1990;5:334-7.
10. Berardelli A, Noth J, Thompson PD, et al. Pathophysiology of chorea and bradykinesia in Huntington's disease. Mov Disord 1999b;14:398-403.
11. Berardelli A, Rona S, Inghilleri M, Manfredi M. Cortical inhibition in Parkinson's disease. A study with paired magnetic stimulation. Brain 1996;119:71-7.
12. Boylan LS, Pullman SL, Lisanby SH, Spicknall KE, Sackeim HA. Repetitive transcranial magnetic stimulation to SMA worsens complex movements in Parkinson's disease. Clin Neurophysiol 2001;112:259-64.
13. Britton TC, Thompson PD, Day BL, Rothwell JC, Findley LJ, Marsden CD. Modulation of postural wrist tremors by magnetic stimulation of the motor cortex in patients with Parkinson's disease or essential tremor and in normal subjects mimicking tremor. Ann Neurol 1993;33:473-9.
14. Brown P, Ridding MC, Werhahn KJ, Rothwell JC, Marsden CD. Abnormalities of the balance between inhibition and excitation in the motor cortex of patients with cortical myoclonus. Brain 1996;119:309-17.
15. Byrnes ML, Thickbroom GW, Wilson SA, et al. The corticomotor representation of upper limb muscles in writer's cramp and changes following botulinum toxin injection. Brain 1998;121:977-88.
16. Cantello R, Civardi C, Cavalli A, et al. Cortical excitability in cryptogenic localization-related epilepsy: Interictal transcranial magnetic stimulation studies. Epilepsia 2000;41:694-704.
17. Cantello R, Gianelli M, Bettucci D, Civardi C, De Angelis MS, Mutani R. Parkinson's disease rigidity: Magnetic motor evoked potentials in a small hand muscle. Neurology 1991;41:1449-56.
18. Cantello R, Gianelli M, Civardi C, Mutani R. Focal subcortical reflex myoclonus. A clinical and neurophysiological study. Arch Neurol 1997;54:187-96.
19. Cantello R, Gianelli M, Civardi C, Mutani R. Pathophysiology of Parkinson's disease rigidity. Role of corticospinal motor projections. In: Battistin L, Scarlato G, Caraceni T, Ruggieri S, eds. Parkinson's Disease. Advances in Neurology. Vol. 69. Philadelphia: Lippincott-Raven, 1996:129-33.
20. Cantello R, Gianelli M, Civardi C, Mutani R. Parkinson's disease rigidity: EMG in a small hand muscle at "rest." Electroencephalogr Clin Neurophysiol 1995;97:215-22.
21. Cantello R, Gianelli M, Civardi C, Mutani R. Magnetic brain stimulation: The silent period after the motor evoked potential. Neurology 1992;42:1951-9.
22. Cantello R, Tarletti R, Civardi C. Transcranial magnetic stimulation and Parkinson's disease. Brain Res Rev 2002;38:309-27.
23. Caramia MD, Bernardi G, Zarola F, Rossini PM. Neurophysiological evaluation of the central nervous impulse propagation in patients with sensorimotor disturbances. Electroencephalogr Clin Neurophysiol 1988;70:16-25.
24. Chen R, Garg RR, Lozano AM, Lang AE. Effects of internal globus pallidus stimulation on motor cortex excitability. Neurology 2001a;56:716-23.
25. Chen R, Kumar S, Garg RG, Lang AE. Impairment of motor cortex activation and deactivation in Parkinson's disease. Clin Neurophysiol 2001;112:600-7.
26. Chen R, Wassermann EM, Canos M, Hallett M. Impaired inhibition in writer's cramp during voluntary muscle activation. Neurology 1997;49:1054-9.
27. Chen R, Yaseen Z, Cohen LG, Hallett M. Time course of corticospinal excitability in reaction time and self-paced movements. Ann Neurol 1998;44:317-25.
28. Chen J, Yu H, Wu Z, Kao K, Hallett M, Liao K. Modulation of symptomatic palatal tremor by magnetic stimulation of the motor cortex. Clin Neurophysiol 2000;111:1191-7.
29. Chu N. Motor evoked potentials in Wilson's disease: Early and late motor responses. J Neurol Sci 1990;99:259-69.
30. Civardi C, Cantello R, Asselmann P, Rothwell JC. Transcranial magnetic stimulation can be used to test connections to primary motor areas from frontal and medial cortex in humans. Neuroimage 2001;14:1444-53.
31. Clouston PD, Lim CL, Sue C, Morris JGL, Yannikas C. Apomorphine can increase cutaneous inhibition of motor activity in Parkinson's disease. Electroencephalogr Clin Neurophysiol 1996;101:8-15.
32. Cockerell OC, Rothwell JC, Thompson PD, Marsden CD, Shorvon SD. Clinical and physiological features of epilepsia partialis continua. Cases ascertained in the UK. Brain 1996;119:393-407.
33. Cruz Martinez A, Arpa J, Alonso M, Palomo F, Villoslada C. Transcranial magnetic stimulation in multiple system and late onset cerebellar atrophies. Acta Neurol Scand 1995;92:218-24.
34. Cruz Martinez A, Palau F. Central motor conduction time by magnetic stimulation of the cortex and peripheral nerve conduction follow-up studies in Friedreich's ataxia. Electroencephalogr Clin Neurophysiol 1997;105:458-61.
35. Cunnington R, Iansek R, Thickbroom GW, et al. Effects of magnetic stimulation over supplementary motor area on movement in Parkinson's disease. Brain 1996;199:815-22.
36. Currà A, Romaniello A, Berardelli A, Cruccu G, Manfredi M. Shortened cortical silent period in facial muscle of patients with cranial dystonia. Neurology 2000;54:130-5.
37. Davey NJ, Puri BK, Lewis HS, Lewis SW, Ellaway PH. Effects of antipsychotic medication on electromyographic responses to transcranial magnetic stimulation of the motor cortex in schizophrenia. J Neurol Nearosurg Psychiatry 1997;63:468-73.
38. Day BL, Dressier D, Maertens de Noordhout A, et al. Electric and magnetic stimulation of human motor cortex: Surface EMG and single motor unit responses. J Physiol (Lond) 1989;412:449-73.
39. Day BL, Rothwell JC, Thompson PD, et al. Motor cortex stimulation in intact man. II. Multiple descending volleys. Brain 1987;110:1191-209.
40. Delwaide PJ, Olivier E. Conditioning transcranial cortical stimulation (TCCS) by exteroceptive stimulation in parkinsonian patients. In: Striefler MB, Korczyn AD, Melamed E, eds. Parkinson's Disease: Anatomy, Pathology and Therapy. Advances in Neurology. Vol. 53. New York: Raven Press, 1994:175-81.
41. Dick JPR, Cowan JMA, Day BL, et al. The corticomotoneurone connection is normal in Parkinson disease. Nature 1984;310:407-9.
42. Di Lazzaro V, Restuccia D, Molinari M, et al. Excitability of the motor cortex to magnetic stimulation in patients with cerebellar lesions. J Neurol Neurosurg Psychiatry. 1994;57:108-10.
43. Diószeghy P, Hidasi E, Mechler F. Study of central motor functions using magnetic stimulation in Parkinson's disease. Electromyogr Clin Neurophysiol 1999;39:101-5.
44. Eisen A, Bohlega S, Bloch M, Hayden M. Silent periods, long-latency reflexes and cortical MEPs in Huntington's disease and at-risk relatives. Electroencephalogr Clin Neurophysiol 1989;74:444-9.
45. Eisen A, Siejka S, Schulzer M, Calne D. Age-dependent decline in motor evoked potential (MEP) amplitude: With a comment on changes in Parkinson's disease. Electroencephalogr Clin Neurophysiol 1991;81:209-15.
46. Ellaway PH, Davey NJ, Maskill DW, Dick JPR. The relation between bradykinesia and excitability of the motor cortex assessed using transcranial magnetic stimulation in normal and parkinsonian subjects. Electroencephalogr Clin Neurophysiol 1995;97:169-78.
47. Entezari-Taher M, Singleton JR, Jones CR, Meekins G, Petajan JH, Smith AG. Changes in excitability of motor cortical circuitry in primary restless legs syndrome. Neurology 1999;53:1201-5.
48. Eyre JA, Kerr AM, Miller S, O'Sullivan MC, Ramesh V. Neurophysiological observations on corticospinal projections to the upper limb in subjects with Rett syndrome. J Neurol Neurosurg Psychiatry 1990;53:874-9.
49. Filipovic SR, Ljubisavljevic M, Svetel M, Milanovic S, Kacar A, Kostic VS. Impairment of cortical inhibition in writer's cramp as revealed by changes in electromyographic silent period after transcranial magnetic stimulation. Neurosci Lett 1997;222:167-70.
50. George MS, Randy Sallee F, Nahas Z, Oliver NC, Wassermann EM. Transcranial magnetic stimulation as a research tool in Tourette syndrome and related disorders. In: Cohen DJ, Goetz CG, Jankovic J, eds. Tourette Syndrome. Philadelphia: Lippincott Wilkins & Williams, 2001:225-35.
51. Ghabra MB, Hallett M, Wassermann EM. Simultaneous repetitive transcranial magnetic stimulation does not speed fine movement in PD. Neurology 1999;52:768-70.
52. Gilio F, Currà A, Lorenzano C, Modugno N, Manfredi M, Berardelli A. Effects of botulinum toxin type A on intracortical inhibition in patients with dystonia. Ann Neurol 2000;48:20-6.
53. Gilio F, Romeo S, Pedace F, Ozkaynak S, Inghilleri M, Berardelli A. Repetitive transcranial magnetic stimulation and cortical excitability in Parkinson's disease. Mov Disord 1998;13(Suppl 2):122.
54. Greenberg BD, Ziemann U, Corà-Locatelli G, et al. Altered cortical excitability in obsessive-compulsive disorder. Neurology 2000;54:142-7.
55. Guerrini R, Bonanni P, Parmeggiani L, Santucci M, Parmeggiani A, Sartucci F. Cortical reflex myoclonus in Rett syndrome. Ann Neurol 1998;43:472-9.
56. Hanajima R, Ugawa J, Terao Y, et al. Intracortical inhibition of the motor cortex is normal in chorea. J Neurol Neurosurg Psychiatry 1999;66:783-6.
57. Hanajima R, Ugawa Y, Terao Y, et al. Cortico-cortical inhibition of motor cortical area projecting to sternocleidomastoid muscle in normal subjects and patients with spasmodic torticollis or essential tremor. Electroencephalogr Clin Neurophysiol 1998;109:391-6.
58. Hanajima R, Ugawa Y, Terao Y, Ogata K, Kanazawa I. Ipsilateral cortico-cortical inhibition of the motor cortex in various neurological disorders. J Neurol Sci 1996;140:109-16.
59. Hefter H, Roick H, van Giesen HJ, et al. Motor impairment in Wilson's disease 3: The clinical impact of pyramidal tract involvement. Acta Neurol Scand 1994;89:421-8.
60. Heinen F, Korinthenberg R. Does transcranial magnetic stimulation allow early diagnosis of Rett syndrome? Neuropediatrics 1996;27:223-4.
61. Heinen F, Petersen H, Fietzek U, Mall V, Schulte-Monting J, Korinthenberg R. Transcranial magnetic stimulation in patients with Rett syndrome: Preliminary results. Eur Child Adolesc Psychiatry 1997;6(Suppl 1):61-3.
62. Homberg V, Lange HW. Central motor conduction to hand and leg muscles in Huntington's disease. Mov Disord 1990;5:214-8.
63. Hu MTM, Bland J, Clough C, Ellis CM, Chaudhuri KR. Limb contractures in levodopa-responsive parkinsonism: A clinical and investigational study of seven new cases. J Neurol 1999;246:671-6.
64. Ikoma K, Mano Y, Takayanagi T. Pulsed magnetic stimulation and F waves in Parkinson's disease. Intern Med 1994;33:77-81.
65. Ikoma K, Samii A, Mercuri B, Wassermann EM, Hallett M. Abnormal cortical motor excitability in dystonia. Neurology 1996;46:1371-6.
66. Inghilleri M, Mattia D, Berardelli A, Manfredi M. Asymmetry of cortical excitability revealed by transcranial stimulation in a patient with focal motor epilepsy and cortical myoclonus. Electroencephalogr Clin Neurophysiol 1998;109:70-2.
67. Kandler RH, Jarrat JA, Sagar HJ, et al. Abnormalities of central motor conduction in Parkinson's disease. J Neurol Sci 1990;100:94-7.
68. Kleine BU, Praamstra P, Stegeman DF. Impaired motor cortical inhibition in Parkinson's disease: Motor unit responses to transcranial magnetic stimulation. Exp Brain Res 2001;138:477-83.
69. Koster B, Lauk M, Timmer J, et al. Central mechanisms in human enhanced physiological tremor. Neurosci Lett 1998;241:135-8.
70. Kujirai T, Caramia MD, Rothwell JC, et al. Corticocortical inhibition in human motor cortex. J Physiol (Lond) 1993;471:501-19.
71. Levy LM, Hallett M. Impaired brain GABA in focal dystonia. Ann Neurol 2002;51:93-101.
72. Liepert J, Wessel F, Schwenkreis P, et al. Reduced intracortical facilitation in patients with cerebellar degeneration. Acta Neurol Scand 1998;98:318-23.
73. Logullo F, Di Bella P, Provinciali L. Motor evoked potentials in a case of stiff-man syndrome: A longitudinal study. Ital J Neurol Sci 1999;20:133-8.
74. Mally J, Stone TW. Improvement in parkinsonian symptoms after repetitive transcranial magnetic stimulation. J Neurol Sci 1999a;162:179-84.
75. Mally J, Stone TW. Therapeutic, "dose dependent" effect of repetitive microelectroshock induced by transcranial magnetic stimulation in Parkinson's disease. J Neurosci Res 1999b;57:935-40.
76. Manfredi L, Garavaglia P, Beretta S, Pellegrini G. Increased cortical inhibition induced by apomorphine in patients with Parkinson's disease. Neurophysiol Clin 1998;28:31-8.
77. Manganotti P, Tamburin S, Zanette G, Fiaschi A. Hyperexcitable cortical responses in progressive myoclonic epilepsy. Neurology 2001;57:1793-9.
78. Manto M, Setta F, Legros B, Jacquy J, Godaux E. Resetting of orthostatic tremor associated with cerebellar cortical atrophy by transcranial magnetic stimulation. Arch Neurol 1999;56:1497-500.
79. Marchese R, Trompetto C, Buccolieri A, Abbruzzese G. Abnormalities of motor cortical excitability are not correlated with clinical features in atypical parkinsonism. Mov Disord 2000;15:1210-4.
80. Marsden CD. The mysterious motor function of the basal ganglia: The Robert Wartenberg lecture. Neurology 1982;32:514-39.
81. Mavroudakis N, Caroyer JM, Brunko E, Zegers de Beyl D. Abnormal motor evoked responses to transcranial magnetic stimulation in focal dystonia. Neurology 1995;45:1671-7.
82. Meyer BU, Britton TC, Benecke R. Wilson's disease: Normalisation of cortically evoked motor responses with treatment. J Neurol 1991a;238:327-30.
83. Meyer BU, Britton TC, Bischoff C, Machetanz JM, Benecke R, Conrad B. Abnormal conduction in corticospinal pathways in Wilson's disease: Investigation of nine cases with magnetic brain stimulation. Mov Disord 1991;6:320-3.
84. Meyer BU, Irlbacher K, Meierkord H. Analysis of stimuli triggering attacks of paroxysmal dystonia induced by exertion. J Neurol Neurosurg Psychiatry. 2001;70:247-51.
85. Meyer BU, Noth J, Lange HW, et al. Motor responses evoked by magnetic brain stimulation in Huntington's disease. Electroencephalogr Clin Neurophysiol 1992;85:197-208.
86. Mills KR. Magnetic Stimulation of the Nervous System. Oxford: University Press, 1999.
87. Mills KR, Nithi KA. Motor cortex stimulation does not reset primary orthostatic tremor. J Neurol Neurosurg Psychiatry 1997;63:553.
88. Mink JW. The basal ganglia: Focused selection and inhibition of competing activity. Progr Neurobiol 1996;50:381-425.
89. Modugno N, Currà A, Giovannelli M, et al. The prolonged cortical silent period in patients with Huntington's disease. Clin Neurophysiol 2001;112:1470-4.
90. Molinuevo JL, Valls-Solé J, Valldeoriola F. The effect of transcranial magnetic stimulation on reaction time in progressive supranuclear palsy. Clin Neurophysiol 2000;111:2008-13.
91. Nezu A, Kimura S, Takeshita S, Tanaka M. Characteristic response to transcranial magnetic stimulation in Rett syndrome. Electroencephalogr Clin Neurophysiol 1998;109:100-3.
92. Odergren T, Rimpilainen I, Borg J. Sternocleidomastoid muscle responses to transcranial magnetic stimulation in patients with cervical dystonia. Electroencephalogr Clin Neurophysiol 1997;105:44-52.
93. Pascual-Leone A, Valls-Solé J, Brasil-Neto JP, Cammarota A, Grafman J, Hallett M. Akinesia in Parkinson's disease. II. Effects of subthreshold repetitive transcranial motor cortex stimulation. Neurology 1994a;44:892-8.
94. Pascual-Leone A, Valls-Solé J, Brasil-Neto JP, Cohen LG, Hallett M. Akinesia in Parkinson's disease. I. Shortening of simple reaction time with focal, single-pulse transcranial magnetic stimulation. Neurology 1994b;44:884-91.
95. Pascual-Leone A, Valls-Solé J, Toro C, Wassermann EM, Hallett M. Resetting of essential tremor and postural tremor in Parkinson's disease with transcranial magnetic stimulation. Muscle Nerve 1994c;17:800-7.
96. Pascual-Leone A, Valls-Solé J, Wassermann EM, Brasil-Neto JP, Cohen LG, Hallett M. Effect of focal transcranial magnetic stimulation on simple reaction time to visual, acoustic and somatosensory stimuli. Brain 1992;115:1045-59.
97. Perretti A, Pellecchia MT, Lanzillo B, Campanella G, Santoro L. Excitatory and inhibitory mechanisms in Wilson's disease: Investigation with magnetic motor cortex stimulation. J Neurol Sci 2001;192:35-40.
98. Pfeiffer G, Hinse P, Humbert T, Riemer G. Neurophysiology of orthostatic tremor. Influence of transcranial magnetic stimulation. Electromyogr Clin Neurophysiol 1999;39:49-53.
99. Porter R, Lemon R. Corticospinal Function and Voluntary Movement. Oxford: Clarendon Press, 1993.
100. Priori A, Berardelli A, Inghilleri M, Accornero N, Manfredi M. Motor cortical inhibition and the dopaminergic system. Pharmacological changes in the silent period after transcranial brain stimulation in normal subjects, patients with Parkinson's disease and drug-induced parkinsonism. Brain 1994a;117:317-23.
101. Priori A, Berardelli A, Inghilleri M, Polidori L, Manfredi M. Electromyographic silent period after transcranial brain stimulation in Huntington's disease. Mov Disord 1994b;9:178-82.
102. Priori A, Polidori L, Rona S, Manfredi M, Berardelli A. Spinal and cortical inhibition in Huntington's chorea. Mov Disord 2000;15:938-46.
103. Provini F, Vetrugno R, Meletti S, et al. Motor pattern of periodic limb movement during sleep. Neurology 2001;57:300-4.
104. Restivo DA, Giuffrida S, Rapisarda G, et al. Central motor conduction to lower limb after transcranial magnetic stimulation in spinocerebellar ataxia type 2 (SCA2). Clin Neurophysiol 2000;111:630-5.
105. Reutens DC, Puce A, Berkovic SF. Cortical hyperexcitability in progressive myoclonus epilepsy: A study with transcranial magnetic stimulation. Neurology 1993;43:186-92.
106. Ridding MC, Inzelberg R, Rothwell JC. Changes in excitability of motor cortical circuitry in patients with Parkinson's disease. Ann Neurol 1995a;37:181-8.
107. Ridding MC, Sheean G, Rothwell JC, Inzelberg R, Kujirai. Changes in the balance between motor cortical excitation and inhibition in focal, task specific dystonia. J Neurol Neurosurg Psychiatry 1995b;59:493-8.
108. Roick H, von Giesen HJ, Lange HW, Benecke R. Postexcitatory inhibition in Huntington's disease. Mov Disord 1992;7:27.
109. Romeo S, Berardelli A, Pedace F, Inghilleri M, Giovannelli M, Manfredi M. Cortical excitability in patients with essential tremor. Muscle Nerve 1998;21:1304-8.
110. Rona S, Berardelli A, Vacca L, Inghilleri M, Manfredi M. Alterations of motor cortical inhibition in patients with dystonia. Mov Disord 1998;13:118-24.
111. Rosenkranz K, Altenmuller E, Siggelkow S, Dengler R. Alteration of sensorimotor integration in musician's cramp: Impaired focusing of proprioception. Clin Neurophysiol 2000;111:2040-5.
112. Rossini PM, Paradiso C, Zarola F, et al. Brain excitability and long latency muscular arm responses: Non-invasive evaluation in healthy and parkinsonian subjects. Electroencephalogr Clin Neurophysiol 1991;81:454-65.
113. Rothwell JC, Hallett M, Berardelli A, Eisen A, Rossini P, Paulus W. Magnetic stimulation: Motor evoked potentials. In: Deuschl G, Eisen A, eds. Recommendations for the practice of clinical neurophysiology. Clin. Neurophysiol 1999;(Suppl 52):97-103.
114. Sandrink F, Syed NA, Fujii MD, Dalakas MC, Floeter MK. Motor cortex excitability in stiff-person syndrome. Brain 2000;123:2231-9.
115. Sanger TD, Garg RR, Chen R. Interactions of two different inhibitory systems in the human motor cortex. J Physiol (Lond) 2001;530:307-17.
116. Schöls L, Amoiridis G, Langkafel M, Schöls S, Przuntek H. Motor evoked potentials in the spinocerebellar ataxias type 1 and type 3. Muscle Nerve 1997;20:226-8.
117. Schwenkreis P, Tegenthoff M, Witscher K, et al. Motor cortex activation by transcranial magnetic stimulation in ataxia patients depends on the genetic defect. Brain 2002;125:301-9.
118. Schwenkreis P, Vorgerd M, Malin JP, Tegenthoff M. Assessment of postexcitatory inhibition in patients with focal dystonia. Acta Neurol Scand 1999;100:260-4.
119. Shiga Y, Tsuda T, Itoyama Y, et al. Transcranial magnetic stimulation alleviates truncal ataxia in spinocerebellar degeneration. J Neurol Neurosurg Psychiatry 2002;72:124-6.
120. Shimamoto H, Morimatsu H, Sugita S, Nakahara K, Shigemori M. Therapeutic effect of repetitive transcranial magnetic stimulation in Parkinson's disease. Rinsho Shinkeigaku 1999;39:1264-7.
121. Siebner HR. Simultaneous repetitive transcranial magnetic stimulation does not speed fine movement in PD. Neurology 2000;54:272.
122. Siebner HR, Auer C, Conrad B. Abnormal increase in the corticomotor output to the affected hand during repetitive transcranial magnetic stimulation of the primary motor cortex in patients with writer's cramp. Neurosci Lett 1999a;262:133-6.
123. Siebner HR, Mentschel C, Auer C, Conrad B. Repetitive transcranial magnetic stimulation has a beneficial effect on bradykinesia in Parkinson's disease. Neuroreport 1999b;10:589-94.
124. Siebner HR, Mentschel C, Auer C, Lehner C, Conrad B. Repetitive transcranial magnetic stimulation causes a short-term increase in the duration of the cortical silent period in patients with Parkinson's disease. Neurosci Lett 2000a;284:147-50.
125. Siebner HR, Rossmeier C, Mentschel C, Peinemann A, Conrad B. Short-term motor improvement after subthreshold 5-Hz repetitive transcranial magnetic stimulation of the primary motor hand area in Parkinson's disease. J Neurol Sci 2000b;178:91-4.
126. Siebner HR, Tormos JM, Ceballos-Baumann AO, et al. Low-frequency repetitive transcranial magnetic stimulation of the motor cortex in writer's cramp. Neurology 1999c;52:529-37.
127. Strafella AP, Valzania F, Nassetti SA, et al. Effects of chronic levodopa and pergolide treatment on cortical excitability in Parkinson's disease: A transcranial magnetic stimulation study. Clin Neurophysiol 2000;111:1198-202.
128. Tassinari CA, Rubboli G, Shibasaki H. Neurophysiology of positive and negative myoclonus. Electroencephalogr Clin Neurophysiol 1998;107:181-95.
129. Tegenthoff M, Vorgerd M, Juskowiak F, Roos V, Malin JP. Postexcitatory inhibition after transcranial magnetic single and double brain stimulation in Huntington's disease. Electroencephalogr Clin Neurophysiol 1996;101:298-303.
130. Terao Y, Hayashi H, Shimizu T, Tanabe H, Hanajima R, Ugawa Y. Altered motor cortical excitability to magnetic stimulation in a patient with a lesion in globus pallidus. J Neurol Sci 1995;129:175-8.
131. Tergau F, Wassermann EM, Paulus W, Ziemann U. Lack of clinical improvement in patients with Parkinson's disease after low- and high-frequency repetitive transcranial magnetic stimulation (Ch. 31). In: Paulus W, Hallet M, Rossini PM, Rothwell JC, eds. Transcranial magnetic stimulation. Clin Neurophysiol 1999a(Suppl 51):281-8.
132. Tergau F, Wischer S, Paulus W. Motor system excitability in patients with restless legs syndrome. Neurology 1999b;52:1060-3.
133. Thompson PD, Day BL, Rothwell JC, Brown P, Britton TC, Marsden CD. The myoclonus in corticobasal degeneration. Evidence for two forms of cortical reflex myoclonus. Brain 1994;117:1197-207.
134. Thompson PD, Dick JPR, Day BL, et al. Electrophysiology of the corticomotoneurone pathways in patients with movement disorders. Mov Disord 1986;1:113-8.
135. Topka H, Mescheriakov S, Boose A, et al. A cerebellar-like terminal and postural tremor induced in normal man by transcranial magnetic stimulation. Brain 1999;122:1551-62.
136. Tsai CH, Semmler JG, Kimber TE, et al. Modulation of primary orthostatic tremor by magnetic stimulation over the motor cortex. J Neurol Neurosurg Psychiatry 1998;64:33-6.
137. Tugnoli V, Manconi, Quatrale R, Eleopra R, Gastaldo E, Tola MR. Neurophysiological study of corticomotor pathway in patients with primary restless legs syndrome [abstract]. Neurology 2000;54(Suppl. 3):A25-6.
138. Ugawa Y, Hanajima R, Kanazawa I. Motor cortex inhibition in patients with ataxia. Electroencephalogr Clin Neurophysiol 1994;93:225-9.
139. Valls-Solé J, Pascual-Leone A, Brasil-Neto JP, Cammarota A, McShane L, Hallett M. Abnormal facilitation of the response to transcranial magnetic stimulation in patients with Parkinson's disease. Neurology 1994;44:735-41.
140. Valls-Solé J, Pascual-Leone A, Wassermann EM, Hallett M. Human motor evoked responses to paired transcranial magnetic stimulation. Electroencephalogr Clin Neurophysiol 1992;85:355-64.
141. Valls-Solé J, Tolosa E, Marti MJ, et al. Examination of motor output pathways in patients with corticobasal degeneration using transcranial magnetic stimulation. Brain 2001;124:1131-7.
142. Valzania F, Strafella AP, Quatrale R, et al. Motor evoked responses to paired cortical magnetic stimulation in Parkinson's disease. Electroencephalogr Clin Neurophysiol 1997;105:37-43.
143. Valzania F, Strafella AP, Tropeani A, Rubboli G, Nassetti SA, Tassinari CA. Facilitation of rhythmic events in progressive myoclonus epilepsy: A transcranial magnetic stimulation study. Clin Neurophysiol 1999;110:152-7.
144. van der Linden C, Bruggeman R, Goldman WH. Alterations of motor evoked potentials by thalamotomy. Electromyogr Clin Neurophysiol 1993;33:329-34.
145. Wassermann EM, Hallett M. Simultaneous repetitive transcranial magnetic stimulation does not speed fine movement in PD [letter]. Neurology 2000;54:273.
146. Wessel K, Tegenthoff M, Vorgerd M, Otto V, Nitschke MF, Malin JP. Enhancement of inhibitory mechanisms in the motor cortex of patients with cerebellar degeneration: A study with transcranial magnetic brain stimulation. Electroencephalogr Clin Neurophysiol 1996;101:273-80.
147. Wu YR, Ashby P, Lang AE. Orthostatic tremor arises from an oscillator in the posterior fossa. Mov Disord 2001;16:272-9.
148. Yokota T, Saito Y, Shimizu Y. Increased corticomotoneuronal excitability after peripheral nerve stimulation in dopa-nonresponsive hemiparkinsonism. J Neurol Sci 1995;129:34-9.
149. Yokota T, Sasaki H, Iwabuchi K, et al. Electrophysiological features of central motor conduction in spinocerebellar atrophy type 1, type 2 and Machado-Joseph disease. J Neurol Neurosurg Psychiatry 1998;65:530-4.
150. Young MS, Triggs WJ, Bowers D, Greer M, Friedman WA. Stereotactic pallidotomy lengthens the transcranial magnetic cortical stimulation silent period in Parkinson's disease. Neurology 1997;49:1278-83.
151. Ziemann U, Koc J, Reimers CD, Finkenstaedt M, Paulus W. Exploration of motor cortex excitability in a diabetic patient with hemiballism-hemichorea. Mov Disord 2000;15:1000-5.
152. Ziemann U, Lonnecker S, Steinhoff BJ, Paulus W. Effects of antiepileptic drugs on motor cortex excitability in humans: A transcranial magnetic stimulation study. Ann Neurol 1996a;40:367-78.
153. Ziemann U, Paulus W, Rothenberger A. Decreased motor inhibition in Tourette disorder: Evidence from transcranial magnetic stimulation. Am J Psychiatry 1997a;154:1277-84.
154. Ziemann U, Rothwell JC, Ridding MC. Interaction between intracortical inhibition and facilitation in human motor cortex. J Physiol (Lond) 1996b;496:873-81.
155. Ziemann U, Tergau F, Burns D, Baudewig J, Paulus W. Changes in human motor cortex excitability induced by dopaminergic and antidopaminergic drugs. Electroencephalogr Clin Neurophysiol 1997b;105:430-7.