Impairment of motor cortex activation and deactivation in Parkinson's disease

Clinical Neurophysiology

Volumn 112, Issue 4, 2001, Pages 600-607

  Chen, Robert ^a,b   Kumar, Sameer ^a   Garg, Rami R ^a   Lang, Anthony E ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

Bradykinesia; Magnetic stimulation; Motor cortex; Parkinson's disease; Reaction time; Voluntary movement

Indexed keywords

ADULT; AGED; ARTICLE; BODY MOVEMENT; BRADYKINESIA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; EVOKED MUSCLE RESPONSE; FEMALE; HUMAN; MALE; MOTOR CORTEX; NERVE EXCITABILITY; PARKINSON DISEASE; PRIORITY JOURNAL; PYRAMIDAL TRACT; REACTION TIME; TRANSCRANIAL MAGNETIC STIMULATION;

ADULT; AGED; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; FEMALE; HUMANS; MAGNETICS; MALE; MIDDLE AGED; MOTOR CORTEX; MOVEMENT; MUSCLE CONTRACTION; MUSCLE, SKELETAL; PARKINSON DISEASE; TIME FACTORS;

EID: 0035080579     PISSN: 13882457     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1388-2457(01)00466-7     Document Type: Article

References (49)

1. Human ballistic arm abduction movements: Effects of L-dopa treatment in Parkinson's disease
2. Simple and complex movements off and on treatment in patients with Parkinson's disease
3. Reaction times and attention in Parkinson's disease
4. Impact of deep brain stimulation on upper limb akinesia in Parkinson's disease
5. A computerised tracking technique for the assessment of Parkinsonian motor disabilities
6. The time course of corticospinal excitability in reaction time and self-paced movements
7. Strength in Parkinson's disease: Relationship to rate of force generation and clinical status
8. Movement-related potentials in Parkinson's disease. Presence and predictability of temporal and spatial cues
9. The Bereitschaftspotential is abnormal in Parkinson's disease
10. Pyramidal tract activity associated with a conditional hand movement in the monkey
11. Reaction time in Parkinson's disease
12. Parkinsonian bradykinesia is due to depression in the rate of rise of muscle activity
13. Behaviour of neurones in monkey periarcuate and precentral cortex before and during visually guided arm and hand movements
14. Order effects in response times of parkinsonian patients and normal controls
15. A physiological mechanism of bradykinesia
16. Studies of sensory and motor cortex physiology: With observations on akinesia in Parkinson's disease
17. Reaction times in Parkinson disease
18. Movement-related potentials recorded from supplementary motor area and primary motor area. Role of supplementary motor area in voluntary movements
19. Simple and choice reaction time and the use of advance information for motor preparation in Parkinson's disease
20. The effect of withdrawal of dopaminergic medication on simple and choice reaction time and the use of advance information in Parkinson's disease
21. Altered force release control in Parkinson's disease
22. Event-related coherence and event-related desynchronization/synchronization in the 10 Hz and 20 Hz EEG during self-paced movements
23. Human corticospinal excitability evaluated with transcranial magnetic stimulation during different reaction time paradigms
24. Response of neurones in the motor cortex during performance of a simple repetitive arm movement
25. Reaction time responses in parkinsonian and hemiparkinsonian patients
26. Akinesia in Parkinsonism. Relation between spontaneous movement (other than tremor) and voluntary movements made on command
27. Reaction time and movement velocity abnormalities in Parkinson's disease under different task conditions
28. Motor initiation versus execution in normal and Parkinson's disease subjects
29. Movement-related change of electrocorticographic activity in human supplementary motor area proper
30. Simple reaction time to focal transcranial magnetic stimulation. Comparison with reaction time to acoustic, visual and somatosensory stimuli
31. Akinesia in Parkinson's disease. I. Shortening of simple reaction time with focal, single-pulse transcranial magnetic stimulation
32. Post-movement beta synchronization. A correlate of an idling motor area?
33. Postmovement beta synchronization in patients with Parkinson's disease
34. Dopaminergic effects on simple and choice reaction time performance in Parkinson's disease
35. Movement amplitude choice reaction time performance in Parkinson's disease may be independent of dopaminergic status
36. Monkey primary motor and premotor cortex: Single-cell activity related to prior information about direction and extent of an intended movement
37. Motor planning is impaired in Parkinson's disease
38. Pre-movement facilitation of motor-evoked potentials in man during transcranial stimulation of the central motor pathways
39. Cortical motor reorganization in akinetic patients with Parkinson's disease: A functional MRI study
40. Spatiotemporal characteristics of sensorimotor neuromagnetic rhythms related to thumb movement
41. Functional segregation of movement-related rhythmic activity in the human brain
42. Desynchronization and recovery of β rhythms during brisk and slow self-paced finger movements in man
43. Enhancement of motor cortical excitability in humans by non-invasive electrical stimulation appears prior to voluntary movement
44. Manual skills in Parkinson's disease
45. Timing of activity in cerebellar dentate nucleus and cerebral motor cortex during prompt volitional movement
46. The role of motor cortex in the pathophysiology of voluntary movement deficits associated with parkinsonism
47. Bradykinesia in Parkinson's disease: Disorders of onset and execution of fast movement
48. Usefulness of movement time in the assessment of Parkinson's disease
49. Delay in simple reaction time after focal transcranial magnetic stimulation of the human brain occurs at the final motor output stage