메뉴 건너뛰기




Volumn 46, Issue 1, 2002, Pages 19-29

Sodium channel blocking and antiarrhythmic actions of the novel arylpiperazine RSD992

Author keywords

Antiarrhythmic; Class I; Frequency dependence; Ischaemia; Sodium channel

Indexed keywords

PIPERAZINE DERIVATIVE; RSD 992; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

EID: 0036421224     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-6618(02)00077-4     Document Type: Article
Times cited : (2)

References (51)
  • 1
    • 0016807588 scopus 로고
    • Electrophysiology and pharmacology of cardiac arrhythmias. VI. Cardiac effects of verapamil
    • Rosen MR, Wit AL, Hoffman BF. Electrophysiology and pharmacology of cardiac arrhythmias. VI. Cardiac effects of verapamil. Am Heart J 1975; 89: 665-73.
    • (1975) Am Heart J , vol.89 , pp. 665-673
    • Rosen, M.R.1    Wit, A.L.2    Hoffman, B.F.3
  • 2
    • 0017071560 scopus 로고
    • Effects of lidocaine, phenytoin and quinidine on ischaemic canine myocardium
    • Hondeghem LM. Effects of lidocaine, phenytoin and quinidine on ischaemic canine myocardium. J Electrocardiol 1976; 9: 203-9.
    • (1976) J Electrocardiol , vol.9 , pp. 203-209
    • Hondeghem, L.M.1
  • 3
    • 0021287507 scopus 로고
    • Antiarrhythmic agents: The modulated receptor mechanism of action of sodium and calcium channel blocking drugs
    • Hondeghem LM, Katzung BG. Antiarrhythmic agents: The modulated receptor mechanism of action of sodium and calcium channel blocking drugs. Annu Rev Pharmacol Toxicol 1987; 24: 387-423.
    • (1987) Annu Rev Pharmacol Toxicol , vol.24 , pp. 387-423
    • Hondeghem, L.M.1    Katzung, B.G.2
  • 4
    • 0027531547 scopus 로고
    • Use-dependent prolongation of ventricular tachycardia cycle length by type I antiarrhythmic drugs in humans
    • Kidwell GA, Greenspon AJ, Greenberg RM, Volosin KJ. Use-dependent prolongation of ventricular tachycardia cycle length by type I antiarrhythmic drugs in humans. Circulation 1993; 87: 118-25.
    • (1993) Circulation , vol.87 , pp. 118-125
    • Kidwell, G.A.1    Greenspon, A.J.2    Greenberg, R.M.3    Volosin, K.J.4
  • 5
    • 0024447633 scopus 로고
    • Efficacy of procainamide on ventricular tachycardia: Relation to prolongation of refractoriness and slowing of conduction
    • Furukawa T, Rosanski JJ, Monroe K, Gasselin AJ, Lister J. Efficacy of procainamide on ventricular tachycardia: Relation to prolongation of refractoriness and slowing of conduction. Am Heart J 1989; 118: 702-8.
    • (1989) Am Heart J , vol.118 , pp. 702-708
    • Furukawa, T.1    Rosanski, J.J.2    Monroe, K.3    Gasselin, A.J.4    Lister, J.5
  • 7
    • 0024825908 scopus 로고
    • Antiarrhythmic properties of tetrodotoxin against occlusion-induced arrhythmias in the rat. A novel approach to the study of the antiarrhythmic effects of ventricular sodium channel blockade
    • Abraham SA, Beatch GN, MacLeod BA, Walker MJA. Antiarrhythmic properties of tetrodotoxin against occlusion-induced arrhythmias in the rat. A novel approach to the study of the antiarrhythmic effects of ventricular sodium channel blockade. J Pharmacol Exp Ther 1989; 251: 1156-73.
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 1156-1173
    • Abraham, S.A.1    Beatch, G.N.2    MacLeod, B.A.3    Walker, M.J.A.4
  • 8
    • 0021365249 scopus 로고
    • Subgroups of class I antiarrhythmic drugs
    • Vaughan-Williams EM. Subgroups of class I antiarrhythmic drugs. Eur Heart J 1984; 5: 96-8.
    • (1984) Eur Heart J , vol.5 , pp. 96-98
    • Vaughan-Williams, E.M.1
  • 9
    • 0019133782 scopus 로고
    • Interval-dependent effects of small antiarrhythmic drugs on excitability of guinea-pig myocardium
    • Courtney KR. Interval-dependent effects of small antiarrhythmic drugs on excitability of guinea-pig myocardium. J Mol Cell Cardiol 1980; 12: 1273-86.
    • (1980) J Mol Cell Cardiol , vol.12 , pp. 1273-1286
    • Courtney, K.R.1
  • 10
    • 0020613124 scopus 로고
    • Importance of physico-chemical properties in determining the kinetics of the effects of class I antiarrhythmic drugs on the maximum rate of depolarization in the guinea pig ventricle
    • Campbell TJ. Importance of physico-chemical properties in determining the kinetics of the effects of class I antiarrhythmic drugs on the maximum rate of depolarization in the guinea pig ventricle. Br J Pharmacol 1983; 80: 33-40.
    • (1983) Br J Pharmacol , vol.80 , pp. 33-40
    • Campbell, T.J.1
  • 11
    • 0008327543 scopus 로고
    • Blockage of sodium channels by sterioisomers of local anesthetics
    • Yeh JZ. Blockage of sodium channels by sterioisomers of local anesthetics. Prog Anesthesiol 1980; 2: 35-44.
    • (1980) Prog Anesthesiol , vol.2 , pp. 35-44
    • Yeh, J.Z.1
  • 12
    • 0023079101 scopus 로고
    • Molecular and structural basis of resting and use-dependent block of sodium current defined using disopyramide analogs
    • Yeh JZ, Ten Eick RE. Molecular and structural basis of resting and use-dependent block of sodium current defined using disopyramide analogs. Biophys J 1987; 51: 123-35.
    • (1987) Biophys J , vol.51 , pp. 123-135
    • Yeh, J.Z.1    Ten Eick, R.E.2
  • 13
    • 0021255108 scopus 로고
    • Frequency-dependent effects of antiarrhythmic drugs on action potential duration and refractoriness of canine cardiac Purkinje fibers
    • Nattel S, Zeng FD. Frequency-dependent effects of antiarrhythmic drugs on action potential duration and refractoriness of canine cardiac Purkinje fibers. J Cardiovasc Pharmacol 1984; 229: 283-91.
    • (1984) J Cardiovasc Pharmacol , vol.229 , pp. 283-291
    • Nattel, S.1    Zeng, F.D.2
  • 14
    • 0023178222 scopus 로고
    • Reduction in sudden death and total mortality by arrhythmic therapy evaluated by electrophysiological drug testing: Criteria of efficacy in patients with sustained ventricular tachyarrhythmia
    • Waller TJ, Kay HR, Speilman SR, Kutalek SP, Greenspan AM, Horowitz LN. Reduction in sudden death and total mortality by arrhythmic therapy evaluated by electrophysiological drug testing: Criteria of efficacy in patients with sustained ventricular tachyarrhythmia. J Am Coll Cardiol 1987; 10: 83-9.
    • (1987) J Am Coll Cardiol , vol.10 , pp. 83-89
    • Waller, T.J.1    Kay, H.R.2    Speilman, S.R.3    Kutalek, S.P.4    Greenspan, A.M.5    Horowitz, L.N.6
  • 15
    • 0026502784 scopus 로고
    • Mexiletine's antifibrillatory actions are limited by the occurrence of convulsions in conscious animals
    • Igwemezie LN, Beatch GN, McErlane KM, Walker MJA. Mexiletine's antifibrillatory actions are limited by the occurrence of convulsions in conscious animals. Eur J Pharmacol 1992; 210: 217-77.
    • (1992) Eur J Pharmacol , vol.210 , pp. 217-277
    • Igwemezie, L.N.1    Beatch, G.N.2    McErlane, K.M.3    Walker, M.J.A.4
  • 16
    • 0028889471 scopus 로고
    • Lack of selectivity for ischaemic tissue limits the antiarrhythmic actions of lidocaine, quinidine and flecainide against ischaemia-induced arrhythmias
    • Barrett TD, Hayes ES, Walker MJA. Lack of selectivity for ischaemic tissue limits the antiarrhythmic actions of lidocaine, quinidine and flecainide against ischaemia-induced arrhythmias. Eur J Pharmacol 1995; 285: 229-38.
    • (1995) Eur J Pharmacol , vol.285 , pp. 229-238
    • Barrett, T.D.1    Hayes, E.S.2    Walker, M.J.A.3
  • 17
    • 0026515794 scopus 로고
    • Cardiovascular actions of the kappa receptor agonist, U-50,488H, in the absence and presence of opioid receptor blockade
    • Pugsley MK, Penz WP, Walker MJA, Wong T-M. Cardiovascular actions of the kappa receptor agonist, U-50,488H, in the absence and presence of opioid receptor blockade. Br J Pharmacol 1992; 105: 521-6.
    • (1992) Br J Pharmacol , vol.105 , pp. 521-526
    • Pugsley, M.K.1    Penz, W.P.2    Walker, M.J.A.3    Wong, T.-M.4
  • 18
    • 0027438288 scopus 로고
    • Cardiovascular actions of U-50,488H and related kappa agonists
    • Pugsley MK, Penz WP, Walker MJA. Cardiovascular actions of U-50,488H and related kappa agonists. Cardiovasc Drug Rev 1993; 11: 151-64.
    • (1993) Cardiovasc Drug Rev , vol.11 , pp. 151-164
    • Pugsley, M.K.1    Penz, W.P.2    Walker, M.J.A.3
  • 19
    • 0029608804 scopus 로고
    • The cardiac electrophysiological effects of sparteine and its analogue BRB-I-28 in the rat
    • Pugsley MK, Saint DA, Hayes E, Berlin KD, Walker MJA. The cardiac electrophysiological effects of sparteine and its analogue BRB-I-28 in the rat. Eur J Pharmacol 1995; 294: 319-27.
    • (1995) Eur J Pharmacol , vol.294 , pp. 319-327
    • Pugsley, M.K.1    Saint, D.A.2    Hayes, E.3    Berlin, K.D.4    Walker, M.J.A.5
  • 20
    • 0015867763 scopus 로고
    • Slow ventricular activation in acute myocardial infarction: A source of reentrant premature ventricular contractions
    • Boineau JP, Cox JL. Slow ventricular activation in acute myocardial infarction: A source of reentrant premature ventricular contractions. Circulation 1973; 48: 702-13.
    • (1973) Circulation , vol.48 , pp. 702-713
    • Boineau, J.P.1    Cox, J.L.2
  • 21
    • 0017695423 scopus 로고
    • Action potentials, after potentials and arrhythmias
    • Cranefield PF. Action potentials, after potentials and arrhythmias. Circ Res 1977; 41: 415-23.
    • (1977) Circ Res , vol.41 , pp. 415-423
    • Cranefield, P.F.1
  • 22
    • 0023908472 scopus 로고
    • Influences of anisotropic tissue structure on reentrant circuits in the epicardial border zone of sub-acute canine infarcts
    • Dillon SM, Allessie MA, Ursel PC, Wit AL. Influences of anisotropic tissue structure on reentrant circuits in the epicardial border zone of sub-acute canine infarcts. Circ Res 1988; 63: 182-206.
    • (1988) Circ Res , vol.63 , pp. 182-206
    • Dillon, S.M.1    Allessie, M.A.2    Ursel, P.C.3    Wit, A.L.4
  • 23
    • 0026573054 scopus 로고
    • Antiarrhythmic effects of U-50,488H in rats subject to coronary artery occlusion
    • Pugsley MK, Penz WP, Walker MJA, Wong T-M. Antiarrhythmic effects of U-50,488H in rats subject to coronary artery occlusion. Eur J Pharmacol 1992; 212: 15-9.
    • (1992) Eur J Pharmacol , vol.212 , pp. 15-19
    • Pugsley, M.K.1    Penz, W.P.2    Walker, M.J.A.3    Wong, T.-M.4
  • 24
    • 0027442543 scopus 로고
    • Electrophysiological and antiarrhythmic actions of the kappa agonist PD129,290, and its R,R(+) enantiomer, PD 129,289
    • Pugsley MK, Saint DA, Penz WP, Walker MJA. Electrophysiological and antiarrhythmic actions of the kappa agonist PD129,290, and its R,R(+) enantiomer, PD 129,289. Br J Pharmacol 1993; 110: 1579-85.
    • (1993) Br J Pharmacol , vol.110 , pp. 1579-1585
    • Pugsley, M.K.1    Saint, D.A.2    Penz, W.P.3    Walker, M.J.A.4
  • 25
    • 85031377824 scopus 로고
    • On the electrophysiological mechanism of action of a novel antiarrhythmic agent-RS 87337
    • Juett JR, Patmore L. On the electrophysiological mechanism of action of a novel antiarrhythmic agent-RS 87337. Br J Pharmacol 1987; 91: 349P.
    • (1987) Br J Pharmacol , vol.91
    • Juett, J.R.1    Patmore, L.2
  • 26
    • 4243297315 scopus 로고
    • Effects of a novel class III and class Ia antiarrhythmic agent RS 87337 in rats and dogs
    • Armstrong JM, Dumez D, Ferrandon P. Effects of a novel class III and class Ia antiarrhythmic agent RS 87337 in rats and dogs. Br J Pharmacol 1987; 91: 395P.
    • (1987) Br J Pharmacol , vol.91
    • Armstrong, J.M.1    Dumez, D.2    Ferrandon, P.3
  • 27
    • 0024372091 scopus 로고
    • Electrophysiologic, antiarrhythmic and cardioprotective effects of N-[3,5 dichlorophenyl]4-[4-hydroxy-2-methoxy-phenyl]piperazine carboxamidine dihydrochloride (RS 87337)
    • Dumez D, Patmore L, Ferrandon P, Allely M, Armstrong JM. Electrophysiologic, antiarrhythmic and cardioprotective effects of N-[3,5 dichlorophenyl]4-[4-hydroxy-2-methoxy-phenyl]piperazine carboxamidine dihydrochloride (RS 87337). J Cardiovasc Pharma-col 1989; 14: 184-93.
    • (1989) J Cardiovasc Pharmacol , vol.14 , pp. 184-193
    • Dumez, D.1    Patmore, L.2    Ferrandon, P.3    Allely, M.4    Armstrong, J.M.5
  • 28
    • 0026596458 scopus 로고
    • A new ECG measure (RSh) for detecting possible sodium channel blockade in vivo in rats
    • Penz WP, Pugsley MK, Hsieh MZ, Walker MJA. A new ECG measure (RSh) for detecting possible sodium channel blockade in vivo in rats. J Pharmacol Methods 1992; 27: 51-8.
    • (1992) J Pharmacol Methods , vol.27 , pp. 51-58
    • Penz, W.P.1    Pugsley, M.K.2    Hsieh, M.Z.3    Walker, M.J.A.4
  • 29
    • 0028578687 scopus 로고
    • Relationship between QαT and RR intervals in rats, guinea pigs, rabbits and primates
    • Hayes E, Pugsley MK, Penz WP, Adaikan G, Walker MJA. Relationship between QαT and RR intervals in rats, guinea pigs, rabbits and primates. J Pharmacol Methods 1994; 32: 201-7.
    • (1994) J Pharmacol Methods , vol.32 , pp. 201-207
    • Hayes, E.1    Pugsley, M.K.2    Penz, W.P.3    Adaikan, G.4    Walker, M.J.A.5
  • 31
  • 32
    • 0026760836 scopus 로고
    • Chimeric study of sodium channels from rat skeletal and cardiac muscle
    • Chen LQ, Chahine M, Kallen RG, Barchi RL, Horn R. Chimeric study of sodium channels from rat skeletal and cardiac muscle. FEBS Lett 1992; 309: 253-7.
    • (1992) FEBS Lett , vol.309 , pp. 253-257
    • Chen, L.Q.1    Chahine, M.2    Kallen, R.G.3    Barchi, R.L.4    Horn, R.5
  • 33
    • 0026732898 scopus 로고
    • Preparation of RNA for injection into Xenopus oocytes
    • Goldin AL, Sumikawa K. Preparation of RNA for injection into Xenopus oocytes. Methods Enzymol 1992; 207: 279-97.
    • (1992) Methods Enzymol , vol.207 , pp. 279-297
    • Goldin, A.L.1    Sumikawa, K.2
  • 36
    • 85047679058 scopus 로고
    • The Lambeth Conventions: Guidelines for the study of arrhythmias in ischaemia
    • Walker MJA, Curtis MJ, Hearse DJ et al. The Lambeth Conventions: Guidelines for the study of arrhythmias in ischaemia. Cardiovasc Res 1988; 22: 447-55.
    • (1988) Cardiovasc Res , vol.22 , pp. 447-455
    • Walker, M.J.A.1    Curtis, M.J.2    Hearse, D.J.3
  • 37
    • 0023732541 scopus 로고
    • Quantification of arrhythmias using scoring systems: An examination of seven scores in an in vivo model of regional myocardial ischaemia
    • Curtis MJ, Walker MJA. Quantification of arrhythmias using scoring systems: An examination of seven scores in an in vivo model of regional myocardial ischaemia. Cardiovasc Res 1988; 22: 656-65.
    • (1988) Cardiovasc Res , vol.22 , pp. 656-665
    • Curtis, M.J.1    Walker, M.J.A.2
  • 39
    • 0021136536 scopus 로고
    • Electrophysiology of O-demethyl encainide in a canine model of sustained ventricular tachycardia
    • Roden DM, Dawson AK, Duff HJ, Woosley RL, Smith RF. Electrophysiology of O-demethyl encainide in a canine model of sustained ventricular tachycardia. J Cardiovasc Pharmacol 1984; 6: 588-95.
    • (1984) J Cardiovasc Pharmacol , vol.6 , pp. 588-595
    • Roden, D.M.1    Dawson, A.K.2    Duff, H.J.3    Woosley, R.L.4    Smith, R.F.5
  • 41
    • 0021321736 scopus 로고
    • Early outward current in rat single ventricular cells
    • Josephson IR, Sanchez-Chapula J, Brown AM. Early outward current in rat single ventricular cells. Circ Res 1984; 54: 157-62.
    • (1984) Circ Res , vol.54 , pp. 157-162
    • Josephson, I.R.1    Sanchez-Chapula, J.2    Brown, A.M.3
  • 42
    • 0034891856 scopus 로고    scopus 로고
    • Three thiadiazinone derivatives, EMD 60417, EMD 66430, and EMD 66398, with class III antiarrhythmic activity but different electrophysiologic profiles
    • Himmel HM, Wettwer E, Lues I, Beier N, Jonas R, Ravens U. Three thiadiazinone derivatives, EMD 60417, EMD 66430, and EMD 66398, with class III antiarrhythmic activity but different electrophysiologic profiles. J Cardiovasc Pharmacol 2001; 38: 438-49.
    • (2001) J Cardiovasc Pharmacol , vol.38 , pp. 438-449
    • Himmel, H.M.1    Wettwer, E.2    Lues, I.3    Beier, N.4    Jonas, R.5    Ravens, U.6
  • 43
    • 0026729245 scopus 로고
    • Quinicainol, a new antiarrhythmic with class I antiarrhythmic actions in the rat
    • Howard PG, MacLeod BA, Walker MJA. Quinicainol, a new antiarrhythmic with class I antiarrhythmic actions in the rat. Eur J Pharmacol 1992; 219: 1-8.
    • (1992) Eur J Pharmacol , vol.219 , pp. 1-8
    • Howard, P.G.1    MacLeod, B.A.2    Walker, M.J.A.3
  • 44
    • 0030609902 scopus 로고    scopus 로고
    • KC8851, a tedisamil analogue with mixed channel blockade, exhibits antiarrhythmic properties against ischemia- and electrically-induced arrhythmias
    • Xu R, Abraham S, McLarnon JG, Walker MJA. KC8851, a tedisamil analogue with mixed channel blockade, exhibits antiarrhythmic properties against ischemia- and electrically-induced arrhythmias. Life Sci 1997; 61: 237-48.
    • (1997) Life Sci , vol.61 , pp. 237-248
    • Xu, R.1    Abraham, S.2    McLarnon, J.G.3    Walker, M.J.A.4
  • 45
    • 0032892813 scopus 로고    scopus 로고
    • RSD1000: A novel antiarrhythmic agent with increased potency under acidic and high-potassium conditions
    • Yong SL, Xu R, McLarnon JG, Zolotoy AB, Beatch GN, Walker MJA. RSD1000: A novel antiarrhythmic agent with increased potency under acidic and high-potassium conditions. J Pharmacol Exp Ther 1999; 289: 236-44.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 236-244
    • Yong, S.L.1    Xu, R.2    McLarnon, J.G.3    Zolotoy, A.B.4    Beatch, G.N.5    Walker, M.J.A.6
  • 46
    • 0025327614 scopus 로고
    • Differential analysis of the frequency-dependent actions of class I antiarrhythmic drugs according to periodic ligand binding: Implications for antiarrhythmic and proarrhythmic efficacy
    • Weirich J, Antoni H. Differential analysis of the frequency-dependent actions of class I antiarrhythmic drugs according to periodic ligand binding: Implications for antiarrhythmic and proarrhythmic efficacy. J Cardiovasc Pharmacol 1990; 15: 998-1009.
    • (1990) J Cardiovasc Pharmacol , vol.15 , pp. 998-1009
    • Weirich, J.1    Antoni, H.2
  • 47
    • 0027288778 scopus 로고
    • Effects of procainamide on the signal-averaged electrocardiogram in relation to the results of programmed ventricular stimulation in patients with sustained monomorphic ventricular tachycardia
    • Kulakowski P, Bahir Y, Heald S, Paul V, Anderson MH, Gibson S, Malik M, Camm AJ. Effects of procainamide on the signal-averaged electrocardiogram in relation to the results of programmed ventricular stimulation in patients with sustained monomorphic ventricular tachycardia. J Am Coll Cardiol 1993; 21: 1428-39.
    • (1993) J Am Coll Cardiol , vol.21 , pp. 1428-1439
    • Kulakowski, P.1    Bahir, Y.2    Heald, S.3    Paul, V.4    Anderson, M.H.5    Gibson, S.6    Malik, M.7    Camm, A.J.8
  • 48
    • 0027178719 scopus 로고
    • Antiarrhythmic effects of selective prolongation of refractoriness. Electrophysiologic actions of sematilide HCl in humans
    • Sager PT, Nademanee K, Antimisiaris M, Pacifico A, Pruitt C, God-frey R, Singh BN. Antiarrhythmic effects of selective prolongation of refractoriness. Electrophysiologic actions of sematilide HCl in humans. Circulation 1993; 88: 1072-82.
    • (1993) Circulation , vol.88 , pp. 1072-1082
    • Sager, P.T.1    Nademanee, K.2    Antimisiaris, M.3    Pacifico, A.4    Pruitt, C.5    Godfrey, R.6    Singh, B.N.7
  • 49
    • 0030805105 scopus 로고    scopus 로고
    • Targeting ischaemia - Cell swelling and drug efficacy
    • Wright AR, Rees SA. Targeting ischaemia - Cell swelling and drug efficacy. Trends Pharmacol Sci 1997; 18: 224-8.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 224-228
    • Wright, A.R.1    Rees, S.A.2
  • 50
    • 0024503496 scopus 로고
    • Voltage-sensitive ion channels
    • Jan LY, Jan YN. Voltage-sensitive ion channels. Cell 1989; 56: 13-25.
    • (1989) Cell , vol.56 , pp. 13-25
    • Jan, L.Y.1    Jan, Y.N.2
  • 51
    • 0028307414 scopus 로고
    • Marked action potential prolongation as a source of injury current leading to border zone arrhythmogenesis
    • Kupersmith J, Li Z-Y, Maldonado C. Marked action potential prolongation as a source of injury current leading to border zone arrhythmogenesis. Am Heart J 1994; 127: 1543-53.
    • (1994) Am Heart J , vol.127 , pp. 1543-1553
    • Kupersmith, J.1    Li, Z.-Y.2    Maldonado, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.