KC8551, a tedisamil analogue with mixed channel blockade, exhibits antiarrhythmogenic properties against ischemia- and electrically-induced arrhythmias

Life Sciences

Volumn 61, Issue 3, 1997, Pages 237-248

  Xu, R ^a   Abraham, S ^a   McLarnon, J G ^a   Walker, M J A ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Antiarrhythmia; K+ currents; KC8551; Na+ currents

Indexed keywords

ANTIARRHYTHMIC AGENT; KC 8851; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION; PROTON; SODIUM CHANNEL BLOCKING AGENT; TEDISAMIL; TEDISAMIL DERIVATIVE; UNCLASSIFIED DRUG; CYCLOPROPANE DERIVATIVE; FUSED HETEROCYCLIC RINGS; POTASSIUM CHANNEL; SODIUM CHANNEL;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROCARDIOGRAM; ELECTROSTIMULATION; HEART INFARCTION; HEART MUSCLE REFRACTORY PERIOD; INTRAVENOUS DRUG ADMINISTRATION; ION CURRENT; ISOLATED HEART; MALE; NONHUMAN; POTASSIUM CURRENT; QRS COMPLEX; QT INTERVAL; RAT; SODIUM CURRENT; ANIMAL; BLOOD PRESSURE; DRUG EFFECT; ELECTROCARDIOGRAPHY; HEART ARRHYTHMIA; HEART MUSCLE ISCHEMIA; HEART RATE; SPRAGUE DAWLEY RAT;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIA; BICYCLO COMPOUNDS, HETEROCYCLIC; BLOOD PRESSURE; CYCLOPROPANES; ELECTRIC STIMULATION; ELECTROCARDIOGRAPHY; HEART RATE; MALE; MYOCARDIAL ISCHEMIA; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNELS;

EID: 0030609902     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(97)00379-2     Document Type: Article

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