Vitamin C and E supplements to lansoprazole-amoxicillin-metronidazole triple therapy may reduce the eradication rate of metronidazole-susceptible Helicobacter pylori infection

Helicobacter

Volumn 7, Issue 5, 2002, Pages 310-316

  Chuang, Chiao Hsiung ^a   Sheu, Bor Shyang ^a,b   Huang, Ay Huey ^a   Yang, Hsiao Bai ^a   Wu, Jiunn Jong ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Gastric inflammation; Helicobacter pylori; Metronidazole; Vitamin C; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; AMOXICILLIN; ANTIBIOTIC AGENT; ASCORBIC ACID; BISMUTH; LANSOPRAZOLE; METRONIDAZOLE; PROBIOTIC AGENT; PROTON PUMP INHIBITOR; RANITIDINE;

ADULT; ANTIBIOTIC SENSITIVITY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; ERADICATION THERAPY; FEMALE; GASTRITIS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HISTOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RASH;

HELICOBACTER; HELICOBACTER PYLORI;

EID: 0036399835     PISSN: 10834389     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-5378.2002.00095.x     Document Type: Article

References (31)

1. Mirvish SS, Wallcave L, Eagen M, Shubic P. Ascorbate-nitrite reaction, possible means of blocking the formation of carcinogenic N-nitroso compounds. Science 1972;177:65-8.
2. Mirvish SS. Effects of vitamin C and E on N-nitroso compound formation, arcinogenesis and cancer. Cancer 1986;58:1842-50.
3. Kyrtopoulos SA. Ascorbic acid and the formation of N-nitroso compounds: Possible role of ascorbic acid in cancer prevention. Am J Clin Nutr 1987;45:1344-50.
4. Rokkas T, Papatheodorou G, Karameris A, Marrogeorgis A, Kalogeropoulos N, Giannikos N. Helicobacter pylori infection and gastric juice vitamin C levels: Impact of eradication. Dig Dis Sci 1995;40:615-21.
5. Phull PS, Price AB, Thormiley MS, Green CJ, Jacyna MR. Vitamin E concentrations in the human stomach and duodenum - correlation with Helicobacter pylori infection. Gut 1996;39:31-5.
6. Zhang ZW, Patchett SE, Perrett D, Katelaris PH, Domizio P, Farthing MJG. The relation between gastric vitamin C concentrations, mucosal histology, and CagA seropositivity in the human stomach. Gut 1998;43:322-6.
7. Sobala GM, Schorah CJ, Shires S, Lynch DA, Gallacher B, Dixon MF, Axon AT. Effect of eradication of Helicobacter pylori on gastric juice ascorbic acid concentrations. Gut 1993;34:1038-41.
8. Zhang HM, Wakisaka N, Maeda O, Yamamoto T. Vitamin C inhibits the growth of a bacterial risk factor for gastric carcinoma: Helicobacter pylori. Cancer 1997;80:1897-902.
9. Sjunnesson H, Sturegard E, Willen R, Wadström T. Antioxidant food supplementation protects against H. pylori infection in guinea pigs. Gut 2000;47:A64.
10. Wang X, Aleljung P, Willen R, Wadström T. Effects of antioxidants against H. pylori infection in BALB/Ca Mice (Abstract). Gut 1998:43(Suppl.):A32.
11. Genta RM, Lew GM, Graham DY. Change in the gastric mucosa following the eradication of H. pylori. Mod Pathol 1993;6:281-9.
12. Forbes GM, Warren JR, Glaser ME, Cullen DJE, Marshall BJ, Collins BJ. Long-term follow-up of gastric histology after H. pylori eradication. J Gastroenterol Hepatol 1996;11:670-3.
13. van der Hulst RW, Ende A, Dekker FW, et al. Effect of Helicobacter pylori eradication on gastritis in relation to cagA: A prospective 1-year follow-up study. Gastroenterology 1997;113:25-30.
14. Sobala GM, Schorah CJ, Sanderson M, et al. Ascorbic acid in the human stomach. Gastroenterology 1989;97:357-63.
15. Bennedsen M, Wang X, Willen R, Wadstrom T, Andersen LP. Treatment of H. pylori infected mice with antioxidant astaxanthin reduces gastric inflammation, bacterial load, and modulates cytokine release by splenocytes. Immunol Lett 1999;70:185-9.
16. 13C-urea breath test is mandatory to detect H. pylori infection of patients after proton pump inhibitor-based triple therapy. Dig Dis Sci 2000;45:1330-6.
17. Yang HB, Sheu BS, Su IJ, Chien CH, Lin XZ. Clinical applications of gastric histology to monitor treatment of dual therapy in H. pylori eradication. Dig Dis Sci 1997;42:1835-40.
18. Huang AH, Sheu BS, Yang HB, Huang CC, Wu JJ, Lin XZ. Impact of H. pylori antimicrobial resistance on the outcome of 1-week lansoprazole-based triple therapy. J Formos Med Assoc 2000;99:704-9.
19. Halliwell B, Gutteridge JMC, Cross CE. Free radicals, antioxidants and human disease: Where are we now? J Laboratory Clin Med 1992;119:598-620.
20. Cohen M, Bhagavan HN. Ascorbic acid and gastrointestinal cancer. J Am Coll Nutr 1995;14:565-78.
21. Drake IM, Davies MJ, Mapstone NP, et al. Ascorbic acid may protect against human gastric cancer by scavenging mucosal oxygen radicals. Carcinogenesis 1996;17:559-62.
22. Mannick EE, Bravo LE, Zarama G, et al. Inducible nitric oxide synthase, nitrotyrosine, and apotosis in Helicobacter pylori gastritis, effects of antibiotics and antioxidants. Cancer Res 1996;56:3238-43.
23. Jarosz M, Dzieniszewski J, Dabrowska-Ufniarz E. Eradication of H. pylori using one-week therapy combining PPI with antibiotics and vitamin C. Gut 2001;49 (Suppl. II:):A69.
24. Gisbert JP, Boixeda D, Martin de Argila C, Redondo C, Moreno L, Abraira V, Garcia Plaza A. New one-week triple therapies with metronidazole for the eradication of Helicobacter pylori: Clarithromycin or amoxycillin as the second antibiotic. Med Clinica 1998;110:1-5.
25. Fock, KM, Chelvam P, Lim SG. Triple therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer disease: Results of a multicentre study in South-East Asia. South-East Asia multicenter Study Group. Aliment Pharmacol Ther 2000;14:225-31.
26. Wong BC, Xiao SD, Hu FL, et al. Comparison of lansoprazole-based triple and dual therapy for treatment of Helicobacter pylori related duodenal ulcer: An Asian multicentre double-blind randomized placebo controlled study. Aliment Pharmacol Ther 2000;14:217-24.
27. Lin BR, Yang JC, Yang JK, Wang JT, Wang TH. Evolution of resistance rate of H. pylori to metronidazole - 3 years' follow-up. Gastroenterol J Taiwan 1997;14:88.
28. Sheu BS, Yang HB, Su IJ, Shiesh SC, Chi CH, Lin XZ. Bacterial density of Helicobacter pylori predicts the success of triple therapy in bleeding duodenal ulcer. Gastrointest Endosc 1996;44:683-8.
29. Kwon DHEL, -zaatari FAK, Kato M, et al. Analysis of rdxA and involvement of additional genes encoding NAD (P) H flavin oxidoreductase (FrxA) and ferredoxin-like protein (FdxB) in metronidazole resistance of Helicobacter pylori. Antimicrob Agents Chemother 2000;44:2133-42.
30. 2, and inhibition of the sodium chloride effect on the glandular stomach by ascorbic acid and betacarotene. J Cancer Res Clin Oncol 1999;125:209-13.
31. Shiesh SC, Sheu BS, Yang HB, Tsao HS. Effect of H. pylori on gastric contents of urea and nitric oxide and oxidative stress (Abstract). Gut 2000;47:A54.