Long-term outcome of gfp gene modified human RPE xenografts into the subretinal space of rabbits

Acta Biochimica et Biophysica Sinica

Volumn 34, Issue 5, 2002, Pages 643-649

  Wang, Feng ^a   Xu, Ping ^a   Wu, Ji Hong ^a   Xia, Xin ^a   Sun, Hao Long ^a   Xu, Xun ^a   Huang, Qian ^a  

^a SHANGHAI FIRST PEOPLE S HOSPITAL   (China)

Author keywords

Gene transfer modify; Green fluorescent protein; Retinal pigment epithelium eye; Transplantation xeno transplantation

Indexed keywords

GREEN FLUORESCENT PROTEIN; PHOTOPROTEIN; TSUKUBAENOLIDE;

ADULT; ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL SURVIVAL; CHOROID; CILIARY DISK; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA MODIFICATION; EYE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENE TRANSFER; GENETIC CODE; GENETIC TRANSFECTION; GENETICS; GRAFT SURVIVAL; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOLOGY; LYMPHOCYTE; LYMPHOCYTIC INFILTRATION; MACROPHAGE; METABOLISM; MICROSCOPY; MONONUCLEAR CELL; NONHUMAN; OPHTHALMOSCOPY; PATHOLOGY; PATHOPHYSIOLOGY; PIGMENT EPITHELIUM; PROTEIN EXPRESSION; RABBIT; REPORTER GENE; RETINA; RETINA NEUROEPITHELIAL LAYER; RETROVIRUS; TIME; TISSUE TRANSPLANTATION; TRANSMISSION ELECTRON MICROSCOPY; TRANSPLANTATION; VITRECTOMY; XENOGRAFT;

ADULT; ANIMALS; EYE; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; LUMINESCENT PROTEINS; PIGMENT EPITHELIUM OF EYE; RABBITS; RETINA; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA; ORYCTOLAGUS CUNICULUS; UNIDENTIFIED RETROVIRUS;

EID: 0036398973     PISSN: 05829879     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Sakmar TP. Restoration of compact discs. Nat Genet, 2000, 25 (3): 245-246
2. Ali RR, Sarra GM, Stephens C, Alwis MD, Bainbridge JW, Munro PM, Fauser S et al. Restoration of photoreceptor ultra-structure and function in retinal degeneration slow mice by gene therapy. Nat Genet, 2000, 25(3): 306-310
3. Liang FQ, Dejneka NS, Cohen DR, Krasnoperova NV, Lem J, Maguire AM, Dudus L et al. AAV-mediated delivery of ciliary neurotrophic factor prolongs photoreceptor survival in the rhodopsin knockout mouse. Mol Ther, 2001, 3(2): 241-248
4. Acland GM, Aguirre GD, Ray J, Zhang Q, Aleman TS, Cideciyan AV, Pearce-Kelling SE et al. Gene therapy restores vision in a canine model of childhood blindness. Nat Genet, 2001, 28(1): 92-95
5. Algvere PV, Gouras P, Dafgard Kopp E. Long-term outcome of RPE allografts in non-immunosuppressed patients with AMD. Eur J Ophthalmol, 1999, 9(3): 217-230
6. Thumann G, Aisenbrey S, Schraermeyer U, Lafaut B, Esser P, Walter P, Bartz-Schmidt KU. Transplantation of autologous iris pigment epithelium after removal of choroidal neovascular membranes. Arch Ophthalmol, 2000, 118(10): 1350-1355
7. Lai CC, Gouras P, Dio K, Tsang SH, Goff SP, Ashton P. Local immunosuppression prolongs survival of RPE xenografts labeled by retroviral gene transfer. Invest Opthalmol Vis Sci, 2000, 41 (10): 3134-3141
8. Crafoord S, Algvere PV, Kopp ED, Seregard S. Cyclosporine treatment of RPE allografts in the rabbit subretinal space. Acta Ophthalmol Scand, 2000, 78(2): 122-129
9. Lai CC, Goruras P, Doi K, Lu F, Kjeldbye H, Goff SP, Pawliuk R et al. Tracking RPE transplants labeled by retroviral gene transfer with green fluorescent protein. Invest Opthalmol Vis Sci, 1999, 40(9): 2141-2146
10. Murata T, Cui J, Taba KE, Oh JY, Spee C, Hinton DR, Ryan SJ. The possibility of gene therapy for the treatment of choroidal neovascularization. Ophthalmology, 2000, 107(7): 1364-1373