Effects of cytoskeletal modifications on Ca2+ influx after cerebral ischemia

Amino Acids

Volumn 23, Issue 1-3, 2002, Pages 325-329

  Fink, K B ^a   Paehr, M ^a   Djoufack, P C ^a   Weissbrich, C ^a   Bosel J ^b   Endres, M ^b  

^a UNIVERSITY OF BONN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Cytochalasin D; F actin; Stroke; Voltage gated Calcium channels

Indexed keywords

CALCIUM ION; CYTOCHALASIN D; N METHYL DEXTRO ASPARTIC ACID; NORADRENALIN; POTASSIUM ION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN ISCHEMIA; BRAIN SLICE; BRAIN SYNAPTOSOME; CALCIUM TRANSPORT; CONFERENCE PAPER; CONTROLLED STUDY; CYTOSKELETON; DEPOLARIZATION; DRUG EFFECT; HEMISPHERE; IN VITRO STUDY; MOUSE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; REPERFUSION; TRANSIENT ISCHEMIC ATTACK; WILD TYPE;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; BIOLOGICAL TRANSPORT; BRAIN ISCHEMIA; CALCIUM; CEREBRAL CORTEX; CYTOCHALASIN D; CYTOSKELETON; GELSOLIN; MICE; MICE, INBRED C57BL; N-METHYLASPARTATE; NOREPINEPHRINE; NUCLEIC ACID SYNTHESIS INHIBITORS; POTASSIUM; SYNAPTOSOMES; TRITIUM;

ANIMALIA;

EID: 0036391764     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-001-0145-z     Document Type: Conference Paper

References (23)

1. Bernstein BW, Bamburg JR (1985) Reorganization of actin in depolarized synaptosomes. J Neurosci 5: 2565-2569
2. Endres M, Namura S, Shimizu-Sasamata M, Waeber C, Zhang L, Gomez-Isla T, Hyman B, Moskowitz MA (1998) Attenuation of delayed neuronal death after mild focal ischemia by inhibitors of the caspase family. J Cereb Blood Flow Metab 18: 238-247
3. Endres M, Fink K, Zhu J, Stagliano NE, Bondada V, Geddes JW, Azuma T, Mattson MP, Kwiatkowski DJ, Moskowitz MA (1999) Neuroprotective effects of gelsolin during murine stroke. J Clin Invest 103: 347-354
4. Fink K, Göthert M (1996) Both ethanol and ifenprodil inhibit NMDA-evoked release of various neurotransmitters at different, yet proportional potency: potential relation to NMDA receptor subunit composition. Naunyn-Schmiedeberg's Arch Pharmacol 354: 312-319
5. Fink K, Göthert M, Molderings G, Schlicker E (1989) N-methyl-D-aspartate (NMDA) receptor-mediated stimulation of noradrenaline release, but not release of other neurotransmitters, in the rat brain cortex: receptor location, characterization and desensitization. Naunyn-Schmiedeberg's Arch Pharmacol 339: 514-521
6. Fink K, Bönisch H, Göthert M (1990) Presynaptic NMDA receptors stimulate noradrenaline release in the cerebral cortex. Eur J Pharmacol 185: 115-117
7. 2+ influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices. Br J Pharmacol 130: 900-906
8. Furukawa K, Fu W, Li Y, Witke W, Kwiatkowski DJ, Mattson MP (1997) The actin-severing protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons. J Neurosci 17: 8178-8186
9. 2+ and glutamate-release of rat cerebrocortical synaptosomes. Neuropharmacology 35: 179-186
10. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450
11. Hara H, Friedlander RM, Gagliardini V, Ayata C, Fink K, Huang Z, Shimizu-Sasamata M, Yuan J, Moskowitz MA (1997) Inhibition of interleukin-1β converting enzyme family proteases reduces ischemic and excitotoxic damage. Proc Natl Acad Sci USA 94: 2007-2012
12. Huang Z, Huang PL, Panahian N, Dalkara T, Fishman MC, Moskowitz MA (1994) Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science 265: 1883-1885
13. 2+. Neuron 10: 797-804
14. +- and veratridine-induced increases of cytosolic calcium concentration in rat cortical synaptosomes. Naunyn-Schmiedeberg's Arch Pharmacol 356: 797-805
15. Obrenovitch TP, Urenjak J, Zilkha E, Jay TM (2000) Excitotoxicity in neurological disorders - the glutamate paradox. Int J Dev Neurosci 18: 281-287
16. Pittaluga A, Raiteri M (1992) N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. I: Location on axon terminals and pharmacological characterization. J Pharmacol Exp Ther 260: 232-237
17. Rosenmund C, Westbrook GL (1993) Calcium-induced actin depolymerization reduces NMDA channel activity. Neuron 10: 805-814
18. Rossi DJ, Oshima T, Attwell D (2000) Glutamate release in severe brain ischaemia is mainly by reversed uptake. Nature 403: 316-321
19. Stevenson BR, Begg DA (1994) Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells. J Cell Sci 107: 367-375
20. Stossel TP (1993) On the crawling of animal cells. Science 260: 1086-1094
21. Vitale ML, Rodriguez Del Castillo A, Tchakarov L, Trifaro JM (1991) Cortical filamentous actin disassembly and scinderin redistribution during chromaffin cell stimulation precede exocytosis, a phenomenon not exhibited by gelsolin. J Cell Biol 113: 1057-1067
22. Witke W, Sharpe AH, Hartwig JH, Azuma T, Stossel TP, Kwiatkowski DJ (1995) Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin. Cell 81: 41-51
23. Zipfel GJ, Lee JM, Choi DW (1999) Reducing calcium overload in the ischemic brain. N Engl J Med 341: 1543-1544