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1
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0025262173
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Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): A vehicle for direct determination of three-dimensional structure
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Hendrickson W.A., Horton J.R., LeMaster D.M. Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three-dimensional structure. EMBO J. 9:1990;1665-1672.
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EMBO J
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Hendrickson, W.A.1
Horton, J.R.2
Lemaster, D.M.3
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2
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0026095584
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Determination of macromolecular structures from anomalous diffraction of synchrotron radiation
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Hendrickson W.A. Determination of macromolecular structures from anomalous diffraction of synchrotron radiation. Science. 254:1991;51-58.
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(1991)
Science
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Hendrickson, W.A.1
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3
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0028986780
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Structural basis of cell-cell adhesion by cadherins
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Shapiro L., Fannon A.M., Kwong P.D., Thompson A., Lehmann M.S., Grübel G., Legrand J-F., Als-Nielsen J., Colman D.R., Hendrickson W.A. Structural basis of cell-cell adhesion by cadherins. Nature. 374:1995;327-337.
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(1995)
Nature
, vol.374
, pp. 327-337
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Shapiro, L.1
Fannon, A.M.2
Kwong, P.D.3
Thompson, A.4
Lehmann, M.S.5
Grübel, G.6
Legrand, J.-F.7
Als-Nielsen, J.8
Colman, D.R.9
Hendrickson, W.A.10
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4
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0033151873
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Taking MAD to the extreme: Ultrafast protein structure determination
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An excellent review on recent advances in synchrotron instrumentation and techniques that will probably provide the basis for much of the high-throughput structure determination efforts of structural genomics projects.
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Walsh M.A., Dementieva I., Evans G., Sanishvili R., Joachimiak A. Taking MAD to the extreme: ultrafast protein structure determination. Acta Crystallogr D Biol Crystallogr. 55:1999;1168-1173. An excellent review on recent advances in synchrotron instrumentation and techniques that will probably provide the basis for much of the high-throughput structure determination efforts of structural genomics projects.
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(1999)
Acta Crystallogr D Biol Crystallogr
, vol.55
, pp. 1168-1173
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Walsh, M.A.1
Dementieva, I.2
Evans, G.3
Sanishvili, R.4
Joachimiak, A.5
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5
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0015459902
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The crystal and molecular structure of DIP-inhibited bovine trypsin at 2.7 Angstrom resolution
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Stroud R.M., Kay L.M., Dickerson R.E. The crystal and molecular structure of DIP-inhibited bovine trypsin at 2.7 Angstrom resolution. Cold Spring Harb Symp Quant Biol. 36:1972;125-140.
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(1972)
Cold Spring Harb Symp Quant Biol
, vol.36
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Stroud, R.M.1
Kay, L.M.2
Dickerson, R.E.3
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6
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0028582185
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Crystal structure of the tyrosine kinase domain of the human insulin receptor
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[see comments]
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Hubbard S.R., Wei L., Ellis L., Hendrickson W.A. Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature. 372:1994;746-754. [see comments].
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(1994)
Nature
, vol.372
, pp. 746-754
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Hubbard, S.R.1
Wei, L.2
Ellis, L.3
Hendrickson, W.A.4
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7
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0027943510
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The crystal structure of the bacterial chaperonin GroEL at 2.8 Å
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[see comments]
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Braig K., Otwinowski Z., Hegde R., Boisvert D.C., Joachimiak A., Horwich A.L., Sigler P.B. The crystal structure of the bacterial chaperonin GroEL at 2.8 Å Nature. 371:1994;578-586. [see comments].
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(1994)
Nature
, vol.371
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Braig, K.1
Otwinowski, Z.2
Hegde, R.3
Boisvert, D.C.4
Joachimiak, A.5
Horwich, A.L.6
Sigler, P.B.7
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8
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0029937037
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Structural analysis of substrate binding by the molecular chaperone DnaK
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Zhu X., Zhao X., Burkholder W.F., Gragerov A., Ogata C.M., Gottesman M.E., Hendrickson W.A. Structural analysis of substrate binding by the molecular chaperone DnaK. Science. 272:1996;1606-1614.
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(1996)
Science
, vol.272
, pp. 1606-1614
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Zhu, X.1
Zhao, X.2
Burkholder, W.F.3
Gragerov, A.4
Ogata, C.M.5
Gottesman, M.E.6
Hendrickson, W.A.7
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9
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0025183708
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Basic local alignment search tool
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Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. J Mol Biol. 215:1990;403-410.
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(1990)
J Mol Biol
, vol.215
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Altschul, S.F.1
Gish, W.2
Miller, W.3
Myers, E.W.4
Lipman, D.J.5
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10
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0028116101
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Quantification of tertiary structural conservation despite primary sequence drift in the globin fold
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Aronson H.E., Royer W.E. Jr., Hendrickson W.A. Quantification of tertiary structural conservation despite primary sequence drift in the globin fold. Protein Sci. 3:1994;1706-1711.
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(1994)
Protein Sci
, vol.3
, pp. 1706-1711
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Aronson, H.E.1
Royer W.E., Jr.2
Hendrickson, W.A.3
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11
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0032510463
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The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor
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This work provides an early example of putative functional assignment by structure-based functional genomics. A protein (AdipoQ/Acrp30) identified by high-throughput sequencing from a fat cell-specific library was subjected to X-ray crystallographic analysis. The structure revealed similarity to TNF-family cytokines, and thus the hypothesis was formed that this protein might function as a cytokine.
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Shapiro L., Scherer P.E. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr Biol. 8:1998;335-338. This work provides an early example of putative functional assignment by structure-based functional genomics. A protein (AdipoQ/Acrp30) identified by high-throughput sequencing from a fat cell-specific library was subjected to X-ray crystallographic analysis. The structure revealed similarity to TNF-family cytokines, and thus the hypothesis was formed that this protein might function as a cytokine.
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(1998)
Curr Biol
, vol.8
, pp. 335-338
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Shapiro, L.1
Scherer, P.E.2
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12
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0028860968
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Structure and ligand recognition of the phosphotyrosine binding domain of Shc
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Zhou M.M., Ravichandran K.S., Olejniczak E.F., Petros A.M., Meadows R.P., Sattler M., Harlan J.E., Wade W.S., Burakoff S.J., Fesik S.W. Structure and ligand recognition of the phosphotyrosine binding domain of Shc. Nature. 378:1995;584-592.
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(1995)
Nature
, vol.378
, pp. 584-592
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Zhou, M.M.1
Ravichandran, K.S.2
Olejniczak, E.F.3
Petros, A.M.4
Meadows, R.P.5
Sattler, M.6
Harlan, J.E.7
Wade, W.S.8
Burakoff, S.J.9
Fesik, S.W.10
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13
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0033522219
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Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase
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[see comments]
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Meng W., Sawasdikosol S., Burakoff S.J., Eck M.J. Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase. Nature. 398:1999;84-90. [see comments].
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(1999)
Nature
, vol.398
, pp. 84-90
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Meng, W.1
Sawasdikosol, S.2
Burakoff, S.J.3
Eck, M.J.4
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14
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0029164589
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Considerations on the folding topology and evolutionary origin of cadherin domains
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Shapiro L., Kwong P.D., Fannon A.M., Colman D.R., Hendrickson W.A. Considerations on the folding topology and evolutionary origin of cadherin domains. Proc Natl Acad Sci USA. 92:1995;6793-6797.
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(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 6793-6797
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Shapiro, L.1
Kwong, P.D.2
Fannon, A.M.3
Colman, D.R.4
Hendrickson, W.A.5
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15
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0038497542
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Molecular structure of nucleic acids: A structure for deoxyribose nucleic acid
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Watson J.D., Crick F.H.C. Molecular structure of nucleic acids: a structure for deoxyribose nucleic acid. Nature. 171:1953;737-738.
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(1953)
Nature
, vol.171
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Watson, J.D.1
Crick, F.H.C.2
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16
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0031570668
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MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family
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Lima C.D., D'Amico K.L., Naday I., Rosenbaum G., Westbrook E.M., Hendrickson W.A. MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family. Structure. 5:1997;763-774.
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(1997)
Structure
, vol.5
, pp. 763-774
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Lima, C.D.1
D'Amico, K.L.2
Naday, I.3
Rosenbaum, G.4
Westbrook, E.M.5
Hendrickson, W.A.6
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17
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0030831990
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Structure-based analysis of catalysis and substrate definition in the HIT protein family
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Lima C.D., Klein M.G., Hendrickson W.A. Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science. 278:1997;286-290.
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(1997)
Science
, vol.278
, pp. 286-290
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Lima, C.D.1
Klein, M.G.2
Hendrickson, W.A.3
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18
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0032505718
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Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family
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Klein M.G., Yao Y., Slosberg E.D., Lima C.D., Doki Y., Weinstein I.B. Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family. Exp Cell Res. 244:1998;26-32.
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(1998)
Exp Cell Res
, vol.244
, pp. 26-32
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Klein, M.G.1
Yao, Y.2
Slosberg, E.D.3
Lima, C.D.4
Doki, Y.5
Weinstein, I.B.6
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19
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0032431024
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Structure-based assignment of the biochemical function of a hypothetical protein: A test case of structural genomics
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This paper shows one of the results of a pilot structural genomics project on M. janaschii. ATP molecules unexpectedly co-purified with the subject protein, and were revealed in the electron density of the high-resolution crystal structure. The authors hypothesized a potential ATPase activity, and their hypothesis was vindicated by biochemical experiments.
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Zarembinski T.I., Hung L.W., Mueller-Dieckmann H.J., Kim K.K., Yokota H., Kim R., Kim S.H. Structure-based assignment of the biochemical function of a hypothetical protein: a test case of structural genomics. Proc Natl Acad Sci USA. 95:1998;15189-15193. This paper shows one of the results of a pilot structural genomics project on M. janaschii. ATP molecules unexpectedly co-purified with the subject protein, and were revealed in the electron density of the high-resolution crystal structure. The authors hypothesized a potential ATPase activity, and their hypothesis was vindicated by biochemical experiments.
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(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15189-15193
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Zarembinski, T.I.1
Hung, L.W.2
Mueller-Dieckmann, H.J.3
Kim, K.K.4
Yokota, H.5
Kim, R.6
Kim, S.H.7
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20
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0033538576
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The structural era of endocytosis
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Marsh M., McMahon H.T. The structural era of endocytosis. Science. 285:1999;215-220.
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(1999)
Science
, vol.285
, pp. 215-220
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Marsh, M.1
McMahon, H.T.2
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21
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0033560279
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As consortium plans free SNP map of human genome
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Masood E. As consortium plans free SNP map of human genome. Nature. 398:1999;545-546.
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(1999)
Nature
, vol.398
, pp. 545-546
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Masood, E.1
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22
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0027983669
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Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations
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Cho Y., Gorina S., Jeffrey P.D., Pavletich N.P. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science. 265:1994;346-355.
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(1994)
Science
, vol.265
, pp. 346-355
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Cho, Y.1
Gorina, S.2
Jeffrey, P.D.3
Pavletich, N.P.4
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23
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0033575387
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Plant functional genomics
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Somerville C., Somerville S. Plant functional genomics. Science. 285:1999;380-383.
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(1999)
Science
, vol.285
, pp. 380-383
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Somerville, C.1
Somerville, S.2
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24
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0032831070
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Structural genomics: Beyond the human genome project
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An excellent review describing the current state of pilot structural genomics projects, and laying out the bioinformatics and experimental processes required for structural genomics work.
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Burley S.K., Almo S.C., Bonanno J.B., Capel M., Chance M.R., Gaasterland T., Lin D., Sali A., Studier F.W., Swaminathan S. Structural genomics: beyond the human genome project. Nat Genet. 23:1999;151-157. An excellent review describing the current state of pilot structural genomics projects, and laying out the bioinformatics and experimental processes required for structural genomics work.
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(1999)
Nat Genet
, vol.23
, pp. 151-157
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Burley, S.K.1
Almo, S.C.2
Bonanno, J.B.3
Capel, M.4
Chance, M.R.5
Gaasterland, T.6
Lin, D.7
Sali, A.8
Studier, F.W.9
Swaminathan, S.10
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