Fusobacterium varium localized in the colonic mucosa of patients with ulcerative colitis stimulates species-specific antibody

Journal of Gastroenterology and Hepatology (Australia)

Volumn 17, Issue 8, 2002, Pages 849-853

  Ohkusa, Toshifumi ^a   Sato, Nobuhiro ^a   Ogihara, Tatuo ^a   Morita, Koji ^b   Ogawa, Masayuki ^c   Okayasu, Isao ^d  

^a JUNTENDO UNIVERSITY   (Japan)

^b KYORIN UNIVERSITY   (Japan)

^c KAWASAKI CITY INSTITUTE FOR PUBLIC HEALTH   (Japan)

^d KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Fusobacterium varium; Immunohistochemistry; Mucosal microflora; Serum antibody; Ulcerative colitis

Indexed keywords

BACTERIUM ANTIBODY;

ADOLESCENT; ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY PRODUCTION; ARTICLE; BACTERIAL INFECTION; BACTERIUM DETECTION; BACTERIUM ISOLATION; BLOOD ANALYSIS; COLON ADENOMA; COLON BIOPSY; COLON MUCOSA; CONTROLLED STUDY; CORRELATION ANALYSIS; CROHN DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FUSOBACTERIUM VARIUM; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; ISCHEMIC COLITIS; MAJOR CLINICAL STUDY; MALE; OPTICAL DENSITY; PRIORITY JOURNAL; SPECIES DISTRIBUTION; TISSUE DISTRIBUTION; ULCERATIVE COLITIS; WESTERN BLOTTING;

EID: 0036378418     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1746.2002.02834.x     Document Type: Article

References (27)

1. Rubin PH, Present DH. Differential diagnosis of chronic ulcerative colitis and Crohn's disease of the colon: one, two, or many diseases? In: Kirsner JB, Shorter RG, eds. Inflammatory Bowel Disease, 4th edn. Baltimore: Williams & Wilkins, 1995; 355-79.
2. Panwala CM, Jones JC, Viney JL. A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. J. Immunol. 1998; 161: 5733-44.
3. Sadlack B, Merz H, Schorle H, Schimpl A, Feller AC, Horak I. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1998; 75: 253-61.
4. Sellon RK, Tonkonogy S, Schultz M et al. Resident enteric flora are necessary for development of spontaneous colitis and immune system activation in IL-10-deficient mice. Infect. Immun. 1998; 66: 5224-31.
5. Dianda L, Hanby AM, Wright NA, Sebesteny A, Hayday AC, Owen MJ. T cell receptor-αβ-deficient mice fail to develop colitis in the absence of a microbial environment. Am. J. Pathol. 1997; 150: 91-7.
6. van der Wiel-Korstanje JAA, Winkler KC. The faecal flora in ulcerative colitis. J. Med. Microbiol. 1975; 8: 491-501.
7. Burke DA, Axon ATR. Adhesive Escherichia coli in inflammatory bowel disease and infective diarrhoea. Br. Med. J. 1988; 297: 102-7.
8. Mann BJ, Petri WA Jr. The role of microbial adherence factors in gastrointestinal disease. In: Blaser MJ, Smith PD, Ravdin JI, Greenberg HB, Guerrant RL, eds. Infections of the Gastrointestinal Tract. New York: Raven Press, 1995; 99-105.
9. Okayasu I, Hatakeyama S, Yamada M, Ohkusa T, Inagaki Y, Nakaya R. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 1990; 98: 694-702.
10. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-5.
11. Ohkusa T, Okayasu I, Tokoi S, Ozaki Y. Bacterial invasion into the colonic mucosa in ulcerative colitis. J. Gastroenterol. Hepatol. 1993; 8: 116-18.
12. Donnenberg M. Cellular invasion by bacteria: lessons from in vitro models. Gastroenterology 1994; 107: 1193-203.
13. Drusano GL, Standiford HC. Pharmacokinetic profile of imipenem/cilastatin in normal volunteers. Am. J. Med. 1985; 78 (Suppl. 6A): 47-53.
14. Kesado T, Watanabe K, Asahi Y, Isono M, Ueno K. Susceptibilities of anaerobic bacteria to N-formimidoyl thienamycin (MK0787) and to other antibiotics. Antimicrob. Agents Chemother. 1982; 21: 1016-22.
15. Cooke EM. A quantitative comparison of the faecal flora of patients with ulcerative colitis and that of normal persons. J. Pathol. Bacteriol. 1967; 91: 439-44.
16. Keighley MRB, Arabi Y, Dimock F, Burdon DW, Allan RN, Alexander-Williams J. Influence of inflammatory bowel disease on intestinal microflora. Gut 1978; 19: 1099-104.
17. Fabia R, Ar'Rajab A, Johansson M-L, et al. Impairment of bacterial flora in human ulcerative colitis and experimental colitis in the rat. Digestion 1993; 54: 248-55.
18. Schultsz C, van den Berg FM, ten Kate FW, Tytgat GNJ, Dankert J. The intestinal mucus layer from patients with inflammatory bowel disease harbors high numbers of bacteria compared with controls. Gastroenterology 1999; 117: 1089-97.
19. Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984; i: 1311-14.
20. Marshall BJ, Armstrong JA, McGechie DB, Glancy RJ. Attempt to fulfill Koch's postulates for pyloric campylobacter. Med. J. Aust. 1985; 142: 436-9.
21. Chen XG, Correa P, Offerhaus J, et al. Ultrastructure of the gastric mucosa harboring Campylobacter-like organisms. Am. J. Clin. Pathol. 1986; 86: 575-82.
22. Thayer WR Jr, Brown M, Sangree H, Katz J, Hersh T. Escherichia coli O:14 and colon hemagglutination antibodies in inflammatory bowel disease. Gastroenterology 1969; 57: 311-18.
23. Brown WR, Lee E. Radioimmunological measurements of bacterial antibodies. Gastroenterology 1974; 66: 1145-53.
24. Tiwana H, Wilson C, Walmsley RS, et al. Antibody responses to gut bacteria in ankylosing spondylitis, rheumatoid arthritis, Crohn's disease and ulcerative colitis. Rheumatol. Int. 1997; 17: 11-16.
25. Heddle RJ, Shearman DJC. Serum antibodies toEscherichia coli in subjects with ulcerative colitis. Clin. Exp. Immunol. 1979; 38: 22-30.
26. Matuda H, Fujiyama Y, Andoh A, Ushijima T, Kajinami T, Bamba T. Characterization of antibody responses against rectal mucosa-associated bacterial flora in patients with ulcerative colitis. J. Gastroenterol. Hepatol. 2000; 15: 61-8.
27. 13C urea breath test for detection of Helicobacter pylori infection. J. Clin. Microbiol. 1996; 34: 1147-52.