Antibody responses to gut bacteria in ankylosing spondylitis, rheumatoid arthritis, Crohn's disease and ulcerative colitis

Rheumatology International

Volumn 17, Issue 1, 1997, Pages 11-16

  Tiwana, H ^a   Wilson, C ^a   Walmsley, R S ^b   Wakefield, A J ^b   Smith, M S N ^b   Cox, N L ^d   Hudson, M J ^e   Ebringer, A ^a,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE HOSPITAL   (United Kingdom)

^c MIDDLESEX HOSPITAL   (United Kingdom)

^d Royal Hampshire Hospital   (United Kingdom)

^e PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

Ankylosing spondylitis; Inflammatory bowel disease; Klebsiella; Proteus; Rheumatoid arthritis

Indexed keywords

ANTIBODY; HLA B27 ANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ADULT; AGED; ANAEROBIC BACTERIUM; ANKYLOSING SPONDYLITIS; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; CROHN DISEASE; ENTERITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FEMALE; HUMAN; IMMUNOREACTIVITY; INTESTINE FLORA; KLEBSIELLA; KLEBSIELLA PNEUMONIAE; MAJOR CLINICAL STUDY; MALE; MOLECULAR MIMICRY; PATHOGENESIS; PRIORITY JOURNAL; PROTEUS MIRABILIS; RHEUMATOID ARTHRITIS; ULCERATIVE COLITIS;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, BACTERIAL; ARTHRITIS, RHEUMATOID; COLITIS, ULCERATIVE; CROHN DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FEMALE; HUMANS; KLEBSIELLA PNEUMONIAE; MALE; MIDDLE AGED; PROTEUS MIRABILIS; SPONDYLITIS, ANKYLOSING;

EID: 0030998204     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00006845     Document Type: Article

References (40)

1. Trull AK, Ebringer R, Panayi GS, Colthorpe D, James DCO, Ebringer A (1983) IgA antibodies to Klebsiella pneumoniae in ankylosing spondylitis. Scand J Rheumatol 12:249-253
2. Trull AK, Ebringer A, Panayi GS, Ebringer R, James DCO (1984) HLA-B27 and the immune response to enterobacterial antigens in ankylosing spondylitis. Clin Exp Immunol 55:74-80
3. Maki-Ikola O, Lehtinen K, Granfors K, Vainionpaa R, Toivanen P (1991) Bacterial antibodies in ankylosing spondylitis. Clin Exp Immunol 84:472-475
4. Shodjai-Moradi F, Ebringer A, Abuljadayel I (1992) IgA antibody response to Klebsiella in ankylosing spondylitis measured by immunoblotting. Ann Rheum Dis 1:233-237
5. Collado A, Gratacos J, Ebringer A, Rashid T, Sanmarti R, Munoz-Gomez J (1994) Serum IgA anti-Klebsiella antibodies in ankylosing spondylitis patients from Catalonia. Scand J Rheumatol 23:119-123
6. Nissila M, Lahesmaa R, Leirisalo-Repo M, Lehtinen K, Toivanen P, Granfors K (1994) Antibodies to Klebsiella pneumoniae, Escherichia coli and Proteus mirabilis in ankylosing spondylitis: effects of sulfasalazine treatment. J Rheumatol 21:2082-2087
7. Sahly H, Podschun R, Sass R, Broker B, Kekow J, Gross WL, Ullmann U (1994) Serum antibodies to Klebsiella capsular polysaccharides in ankylosing spondylitis. Arthritis Rheum 37: 754-759
8. Maki-Ikola O, Lehtinen K, Nissila M, Granfors K (1994) IgM, IgA, IgG class serum antibodies against Klebsiella pneumoniae and Escherichia coli lipopolysaccharides in patients with ankylosing spondylitis. Br J Rheumatol 33:1025-1029
9. Ibbotson JP, Pease PE, Allan RN (1987) Serological studies in Crohn's disease. Eur J Clin Microbiol 6:286-290
10. Mielants H, Veys EM, Cuvelier C, Vos De M (1988) Ileocolonoscopic findings in seronegative spondylarthropathies. Br J Rheumatol 27 [Suppl II]: 95-105
11. Cooper R, Fraser SM, Sturrock RD, Gemmell CG (1988) Raised titres of anti-Klebsiella IgA in ankylosing spondylitis, rheumatoid arthritis, and inflammatory bowel disease. BMJ 296:1432-1434
12. Mckenzie H, Main J, Pennington CR, Parratt D (1990) Antibody to selected strain of Saccharomyces cerevisiae (baker's and brewer's yeast) and Candida albicans in Crohn's disease. Gut 31:536-538
13. Tabaqchali S, O'Donoghue DP, Bettelheim KA (1978) Escherichia coli antibodies in patients with Crohn's disease. Gut 19:108-113
14. Stainsby KJ, Lowes JR, Allan RN, Ibbotson JP (1993) Antibodies to Mycobacterium paratuberculosis and nine species of environmental Mycobacterium in Crohn's disease and control subjects. Gut 34:371-374
15. Tanka K, Wilks M, Coates PJ, Farthing MJG, Walker-Smith JA, Tabaqchali S (1991) Mycobacterium paratuberculosis and Crohn's disease. Gut 32:43-45
16. Blaser MJ, Miller RA, Lacher J, Singleton JW (1984) Patients with active Crohn's disease have elevated serum antibodies to antigens of seven enteric bacterial pathogens. Gastroenterology 87:888-894
17. Wensinck F, Custers-Van Lieshout LMC, Poppelaars-Kustermans PAJ, Schröder AM (1981) The faecal flora of patients with Crohn's disease. J Hyg 87:1-12
18. Bull K, Matthews N, Rhodes J (1986) Antibody response to anaerobic coccoid rods in Crohn's disease. J Clin Pathol 39: 1130-1134
19. 51Cr-EDTA]) in patients with Crohn's disease and their healthy relatives. Scand J Gastroenterol 24:993-998
20. Khalafpour S, Ebringer A, Abuljadayel I, Corbett M (1988) Antibodies to Klebsiella and Proteus microorganisms in ankylosing spondylitis and rheumatoid arthritis patients measured by ELISA. Br J Rheumatol 27 [Suppl II]:86-89
21. Hartley MG, Hudson MJ, Swarbrick ET, Hill MJ, Gent Hellier MD, Grace RH (1992) The rectal mucosa-associated microflora in patients with ulcerative colitis. J Med Microbiol 36:96-103
22. Mancini G, Carbonara HO, Heremans JF (1965) Immunological quantification of antigens by single radial immunodiffusion. Immunochemistry 2:235-254
23. Rogers P, Hassan J, Bresnihan B, Feighery C, Whelan A (1988) Antibodies to Proteus in rheumatoid arthritis. Br J Rheumatol 27 [Suppl II]:90-94
24. Deighton CM, Gray JW, Bint AJ, Walker DJ (1992) Anti-Proteus antibodies in rheumatoid arthritis same-sexed sibships. Br J Rheumatol 31:241-245
25. Deighton CM, Gray J, Bint AJ, Walker DJ (1992) Specificity of the Proteus antibody response in rheumatoid arthritis. Ann Rheum Dis 51:1206-1207
26. Ebringer A, Ptaszynska T, Corbett M, Wilson C, Macafee Y, Avakian H, Baron P, James DCO (1985) Antibodies to Proteus in rheumatoid arthritis. Lancet II:305-307
27. Subair H, Tiwana H, Fielder M, Binder A, Cunningham K, Ebringer A, Wilson C, Hudson MJ (1995) Elevation in anti-Progteus antibodies in rheumatoid arthritis patients from Bermuda and England. J Rheumatol 22:1825-1828
28. Kjeldsen-Kragh J, Rashid T, Dywad A, Sioud M, Haugen M, Forre O, Ebringer A (1995) Decrease in anti-Proteus mirabilis but not anti-Escherichia coli antibody levels in rheumatoid arthritis patients treated with a vegetarian diet. Ann Rheum Dis 54:221-224
29. Fielder M, Tiwana H, Youinou P, Le Goff P, Deonarain R, Wilson C, Ebringer A (1995) The specificity of the anti-Proteus antibody response in tissue typed rheumatoid arthritis patients from Brest. Rheumatol Int 15:79-82
30. O'Mahony S, Anderson N, Nuki G, Ferguson A (1992) Systemic and mucosal antibodies to Klebsiella in patients with ankylosing spondylitis and Crohn's disease. Ann Rheum Dis 51: 1296-1300
31. Morris AJ, Howden CW, Robertson C, Duncan A, Torley H, Sturrock RD, Russell RI (1991) Increased intestinal permeability in ankylosing spondylitis - primary lesion or drug effect. Gut 32:1470-1472
32. Targan SR, Murphy LK (1993) Clarifying the causes of Crohn's. Nature Med 1:1241-1243
33. Bjarnason I, Williams P, So A, Levi AJ, Peters TJ, Zanelli GD, Gumpel JM, Ansell B (1984) Intestinal permeability and inflammation in rheumatoid arthritis: effects of non-steroidal anti-inflammatory drugs. Lancet I:1171-1174
34. Smith DM, Gibson RA, Brookes PM (1985) Abnormal bowel permeability in ankylosing spondylitis and rheumatoid arthritis. J Rheumatol 12:299-305
35. Munkholm P, Langholz, E, Hollander D, Thornberg K, Orholm M, Katz KD, Binder V (1994) Intestinal permeability in patients with Crohn's disease and ulcerative colitis and their first degree relatives. Gut 35:68-72
36. Kuiper S, Van PJ, Verheesen PE, Rentsch HU, Stockbrugger R, Van der Linden SM (1993) Ankylosing spondylitis and healthy relatives don't show increase in small intestinal permeability with luctulose mannitol test. Clin Exp Rheumatol 11:413-416
37. Finegold SM, Flora DJ, Attebery HR, Sutter VL (1975) Faecal bacteriology of colonic polyp patients and control patients. Cancer Res 35:3407-3417
38. Finegold SM, Sutter VL, Mathisen GE (1983) Normal indigenous intestinal flora. In: Human intestinal flora in health and disease. Academic Press, New York London, pp 3-31
39. Brewerton DA, Caffrey M, Nicholls A, Walters D, James DCO (1974) HL-A 27 and arthropathies associated with ulcerative colitis and psoriasis. Lancet 1:956-957
40. Wilson C, Corbett M, Ebringer A (1990) Increased isolation of Proteus mirabilis species from rheumatoid arthritis patients compared to osteoarthritis patients and healthy controls. Br J Rheumatol 29 [Suppl II]:99