The impact of gene therapy on dentistry: A revisiting after six years

Journal of the American Dental Association

Volumn 133, Issue 1, 2002, Pages 35-44

  Baum, Bruce J ^a   Kok, Marc ^a   Tran, Simon D ^a   Yamano, Seiichi ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; DNA VACCINE;

AUTOIMMUNE DISEASE; FACE PAIN; GENE THERAPY; GENE TRANSFER; GENETICS; HEAD AND NECK TUMOR; HUMAN; KERATINOCYTE; METABOLISM; MOUTH DISEASE; REVIEW; SALIVARY GLAND DISEASE; SJOEGREN SYNDROME; TOOTH DISEASE; VACCINATION;

AUTOIMMUNE DISEASES; BONE MORPHOGENETIC PROTEINS; FACIAL PAIN; GENE THERAPY; GENE TRANSFER TECHNIQUES; HEAD AND NECK NEOPLASMS; HUMANS; KERATINOCYTES; MOUTH DISEASES; SALIVARY GLAND DISEASES; SJOGREN'S SYNDROME; TOOTH DISEASES; VACCINATION; VACCINES, DNA;

EID: 0036362007     PISSN: 00028177     EISSN: None     Source Type: Journal    
DOI: 10.14219/jada.archive.2002.0019     Document Type: Article

References (56)

1. Baum BJ, O'Connell BC. The impact of gene therapy on dentistry. JADA 1995;126:179-89.
2. Cavazzana-Calvo M, Hacein-Bey S, de Saint Basile G, et al. Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. Science 2000;288:669-72.
3. Somia N, Verma IM. Gene therapy: trials and tribulations. Nat Rev Genet 2000;1:91-9.
4. Hackett NR, Kaminsky SM, Sondhi D, Crystal RG. Antivector and antitransgene host responses in gene therapy. Curr Opin Mol Ther 2000;2:376-82.
5. Kay MA, Glorioso JC, Naldini L. Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat Med 2001;7:33-40.
6. Carmen IH. A death in the laboratory: the politics of the Gelsinger aftermath. Mol Ther 2001;3:425-8.
7. Nathan DG, Fontanarosa PB, Wilson JD. Opportunities for medical research in the 21st century. JAMA 2001;285:533-4.
8. Franceschi RT, Wang D, Krebsbach PH, Rutherford RB. Gene therapy for bone formation: in vitro and in vivo osteogenic activity of an adenovirus expressing BMP7. J Cell Biochem 2000;78:476-86.
9. Krebsbach PH, Gu K, Franceschi RT, Rutherford RB. Gene therapy-directed osteogenesis: BMP-7-transduced human fibroblasts form bone in vivo. Hum Gene Ther 2000;11:1201-10.
10. Gazit D, Turgeman G, Kelley P, et al. Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: a novel cell-mediated gene therapy. J Gene Med 1999;1:121-33.
11. Moutsatsos IK, Turgeman G, Zhou S, et al. Exogenously regulated stem cell-mediated gene therapy for bone regeneration. Mol Ther 2001;3:449-61.
12. Alden TD, Beres EJ, Laurent JS, et al. The use of bone morphogenetic protein gene therapy in craniofacial bone repair. J Craniofac Surg 2000;11:24-30.
13. Zhu Z, Lee CS, Tejeda KM, Giannobile WV. Gene transfer and expression of platelet-derived growth factors modulate periodontal cellular activity. J Dent Res 2001;80:892-7.
14. Kagami H, O'Connell BC, Baum BJ. Evidence for the systemic delivery of a transgene product from salivary glands. Hum Gene Ther 1996;7:2177-84.
15. He X, Goldsmith CM, Marmary Y, et al. Systemic action of human growth hormone following adenovirus-mediated gene transfer to rat submandibular glands. Gene Ther 1998;5:537-41.
16. Goldfine ID, German MS, Tseng HC, et al. The endocrine secretion of human insulin and growth hormone by exocrine glands of the gastrointestinal tract. Nat Biotechnol 1997;15:1378-82.
17. O'Connell BC, Xu T, Walsh TJ, et al. Transfer of a gene encoding the anticandidal protein histatin 3 to salivary glands. Hum Gene Ther 1996;7:2255-61.
18. Delporte C, O'Connell BC, He X, et al. Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands. Proc Natl Acad Sci U S A 1997;94:3268-73.
19. Delporte C, Redman RS, Baum BJ. Relationship between the cellular distribution of the α(v) β3/5 integrins and adenoviral infection in salivary glands. Lab Invest 1997;77:167-73.
20. Lillibridge CD, O'Connell BC. In human salivary gland cells, overexpression of E2F1 overcomes an interferon-γ- and tumor necrosis factor-α-induced growth arrest but does not result in complete mitosis. J Cell Physiol 1997;172:343-50.
21. Xiong W, Chao J, Chao L. Expression and localization of human kallistatin in rat submandibular gland after intracapsular gene injection. Biochem Biophys Res Commun 1997;231:494-8.
22. Flock M, Zhang HG, Kern ER, Hsu HC, Muller-Ladner U, Mountz JD. Treatment of chronic sialadenitis in a murine model of Sjögren's syndrome by local FasL gene transfer. Arthritis Rheum 2001;44:964-73.
23. Barka T, Van der Noen HM. Retrovirus-mediated gene transfer into salivary glands in vivo. Hum Gene Ther 1996;7:613-8.
24. Kagami H, Atkinson JC, Michalek SM, et al. Repetitive adenovirus administration to the parotid gland: role of immunological barriers and induction of oral tolerance. Hum Gene Ther 1998;9:305-13.
25. Wang S, Baum BJ, Kagami H, Zheng C, O'Connell BC, Atkinson JC. Effect of clodronate on macrophage depletion and adenoviral-mediated transgene expression in salivary glands. J Oral Pathol Med 1999;28:145-51.
26. O'Connell AC, Baccaglini L, Fox PC, et al. Safety and efficacy of adenovirus-mediated transfer of the human aquaporin-1 cDNA to irradiated parotid glands of non-human primates. Cancer Gene Ther 1999;6:505-13.
27. Wang S, Baum BJ, Yamano S, et al. Adenoviral-mediated gene transfer to mouse salivary glands. J Dent Res 2000;79:701-8.
28. Baum BJ, Berkman ME, Marmary Y, et al. Polarized secretion of transgene products from salivary glands in vivo. Hum Gene Ther 1999;10:2789-97.
29. Hoque AT, Baccaglini L, Baum BJ. Hydroxychloroquine enhances the endocrine secretion of adenovirus-directed growth hormone from rat submandibular glands in vivo. Hum Gene Ther 2001;12:1333-41.
30. Fox PC, Brennan M, Pillemer S, Radfar L, Yamano S, Baum BJ. Sjögren's syndrome: a model for dental care in the 21st century. JADA 1998;129:719-28.
31. Tsokos GC, Nepom GT. Gene therapy in the treatment of autoimmune diseases. J Clin Invest 2000;106:181-3.
32. Yamano S, Baum BJ. Prospects for gene-based immunopharmacology in salivary glands. Jpn J Pharmacol 2000;82:281-6.
33. Firestein GS. VIP: a very important protein in arthritis. Nat Med 2001;7:537-8.
34. Baum BJ, Goldsmith CM, Hoque AT, et al. Salivary glands as a model for craniofacial applications of gene transfer. Int J Oral Maxillofac Surg 2000;29:163-6.
35. Yamano S, Scott DE, Huang LY, et al. Protection from experimental endotoxemia by a recombinant adeno-associated virus encoding interleukin 10. J Gene Med 2001;3:450-7.
36. Fellowes R, Etheridge CJ, Coade S, et al. Amelioration of established collagen induced arthritis by systemic IL-10 gene delivery. Gene Ther 2000;7:967-77.
37. Yamano S, Atkinson JC, Baum BJ, Fox PC. Salivary gland cytokine expression in NOD and normal BALB/c mice. Clin Immunol 1999;92:265-75.
38. Dubner R. Three decades of pain research and its control. J Dent Res 1997;76:730-3.
39. Mannes AJ, Caudle RM, O'Connell BC, Iadarola MJ. Adenoviral gene transfer to spinal-cord neurons: intrathecal vs. intraparenchymal administration. Brain Res 1998;793(1-2):1-6.
40. Finegold AA, Mannes AJ, Iadarola MJ. A paracrine paradigm for in vivo gene therapy in the central nervous system: treatment of chronic pain. Hum Gene Ther 1999;10:1251-7.
41. Ishii K, Isono M, Inoue R, Hori S. Attempted gene therapy for intractable pain: dexamethasone-mediated exogenous control of β-endorphin secretion in genetically modified cells and intrathecal transplantation. Exp Neurol 2000;166:90-8.
42. Goss JR, Mata M, Goins WF, Wu HH, Glorioso JC, Fink DJ. Antinociceptive effect of a genomic herpes simplex virus-based vector expressing human proenkephalin in rat dorsal root ganglion. Gene Ther 2001;8:551-6.
43. Kuboki T, Nakanishi T, Kanyama M, et al. Direct adenovirus-mediated gene delivery to the temporomandibular joint in guinea-pigs. Arch Oral Biol 1999;44:701-9.
44. Gurunathan S, Wu CY, Freidag BL, Seder RA. DNA vaccines: a key for inducing long-term cellular immunity. Curr Opin Immunol 2000;12:442-7.
45. Kawabata S, Terao Y, Fujiwara T, Nakagawa I, Hamada S. Targeted salivary gland immunization with plasmid DNA elicits specific salivary immunoglobulin A and G antibodies and serum immunoglobulin G antibodies in mice. Infect Immun 1999;67:5863-8.
46. Ghazizadeh S, Taichman LB. Virus-mediated gene transfer for cutaneous gene therapy. Hum Gene Ther 2000;11:2247-51.
47. Khavari PA. Genetic correction of inherited epidermal disorders. Hum Gene Ther 2000;11:2277-82.
48. Cao T, Wang XJ, Roop DR. Regulated cutaneous gene delivery: the skin as a bioreactor. Hum Gene Ther 2000;11:2297-300.
49. Freiberg RA, Choate KA, Deng H, Alperin ES, Shapiro LJ, Khavari PA. A model of corrective gene transfer in X-linked ichthyosis. Hum Mol Genet 1997;6:927-33.
50. Seitz CS, Giudice GJ, Balding SD, Marinkovich MP, Khavari PA. BP180 gene delivery in junctional epidermolysis bullosa. Gene Ther 1999;6:42-7.
51. Mizuno H, Emi N, Abe A, et al. Successful culture and sustainability in vivo of gene-modified human oral mucosal epithelium. Hum Gene Ther 1999;10:825-30.
52. Greenlee RT, Murray T, Bolden S, Wingo PA. Cancer statistics, 2000. CA Cancer J Clin 2000;50:7-33.
53. Boyle JO, Hakim J, Koch W, et al. The incidence of p53 mutations increases with progression of head and neck cancer. Cancer Res 1993;53:4477-80.
54. Bischoff JR, Kirn DH, Williams A, et al. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 1996;274:373-6.
55. Heise C, Sampson-Johannes A, Williams A, McCormick F, Von Hoff DD, Kirn DH. ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nat Med 1997;3:639-45.
56. Khuri FR, Nemunaitis J, Ganly I, et al. A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 2000;6:879-85.