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Volumn 7, Issue 1-2, 2002, Pages 68-73
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Development of new insulinomimetic zinc(II) picolinate complexes with a Zn(N2O2) coordination mode: Structure characterization, in vitro, and in vivo studies
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Author keywords
Blood glucose normalizing effect; Insulinomimetic activity; KK Ay mice; Picolinic acid derivatives; Zinc(II) complex
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Indexed keywords
ADRENALIN;
ANTIDIABETIC AGENT;
BIS(3 METHYLPICOLINATO)ZINC;
BIS(6 METHYLPICOLINATO)ZINC;
BIS(PICOLINATO)ZINC;
CARBOXYLIC ACID DERIVATIVE;
FATTY ACID;
GLUCOSE;
NITROGEN DERIVATIVE;
OXYGEN DERIVATIVE;
PYRIDINE DERIVATIVE;
UNCLASSIFIED DRUG;
ZINC DERIVATIVE;
INSULIN;
ORGANOMETALLIC COMPOUND;
PICOLINIC ACID DERIVATIVE;
ZINC;
ADIPOCYTE;
ANIMAL CELL;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ARTICLE;
BLOOD ANALYSIS;
BODY WATER;
CELL ISOLATION;
COMPLEX FORMATION;
CONTROLLED STUDY;
CRYSTALLIZATION;
DOSE RESPONSE;
DRUG ACTIVITY;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
FATTY ACID TRANSPORT;
GENETIC DISORDER;
GEOMETRY;
GLUCOSE BLOOD LEVEL;
HYPERGLYCEMIA;
IC 50;
IN VITRO STUDY;
IN VIVO STUDY;
INSULINOMIMETIC ACTIVITY;
MALE;
NON INSULIN DEPENDENT DIABETES MELLITUS;
NONHUMAN;
ORAL GLUCOSE TOLERANCE TEST;
PRIORITY JOURNAL;
RAT;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
ANIMAL;
CHEMISTRY;
DRUG EFFECT;
EXPERIMENTAL DIABETES MELLITUS;
GLUCOSE TOLERANCE TEST;
METABOLISM;
METHODOLOGY;
MOUSE;
MOUSE STRAIN;
SECRETION;
ANIMALIA;
ADIPOCYTES;
ANIMALS;
BLOOD GLUCOSE;
DIABETES MELLITUS, EXPERIMENTAL;
EPINEPHRINE;
FATTY ACIDS, NONESTERIFIED;
GLUCOSE TOLERANCE TEST;
INSULIN;
MICE;
MICE, INBRED STRAINS;
ORGANOMETALLIC COMPOUNDS;
PICOLINIC ACIDS;
STRUCTURE-ACTIVITY RELATIONSHIP;
ZINC;
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EID: 0036359445
PISSN: 09498257
EISSN: None
Source Type: Journal
DOI: 10.1007/s007750100266 Document Type: Article |
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Times cited : (110)
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References (26)
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