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Journal of Biological Inorganic Chemistry

Volumn 6, Issue 2, 2001, Pages 133-142

A new halogenated antidiabetic vanadyl complex, bis(5-iodopicolinato)oxovanadium(IV): In vitro and in vivo insulinomimetic evaluations and metallokinetic analysis

(7) Takino, Toshikazu a Yasui, Hiroyuki a Yoshitake, Akira a Hamajima, Yoshio a Matsushita, Rokuji b Takada, Jitsuya b Sakurai, Hiromu a

a KYOTO PHARMACEUTICAL UNIVERSITY (Japan)

b KYOTO UNIVERSITY (Japan)

Author keywords

Blood circulation monitoring EPR; Diabetes mellitus; Insulinomimetics; Metallokinetic analysis; Vanadyl iodopicolinate

Indexed keywords

ANTIDIABETIC AGENT; BIS(5 IODOPICOLINATO)OXOVANADIUM; INSULIN; UNCLASSIFIED DRUG; VANADYL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CLEARANCE; HYDROPHOBICITY; HYPERGLYCEMIA; MALE; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

ADIPOSE TISSUE; ANIMALS; BLOOD CIRCULATION; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DRUG EVALUATION, PRECLINICAL; ERYTHROCYTES; FATTY ACIDS, NONESTERIFIED; HYPOGLYCEMIC AGENTS; INHIBITORY CONCENTRATION 50; IODINE; LIGANDS; METABOLIC CLEARANCE RATE; ORGANOMETALLIC COMPOUNDS; PICOLINIC ACIDS; RATS; RATS, WISTAR; SPECTRUM ANALYSIS; STREPTOZOCIN; TISSUE DISTRIBUTION; VANADATES;

ANIMALIA;

EID: 0034840456 PISSN: 09498257 EISSN: None Source Type: Journal
DOI: 10.1007/s007750000182 Document Type: Article

Times cited : (84)

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