메뉴 건너뛰기




Volumn 23, Issue 2, 1997, Pages 113-129

Long-term acting and orally active vanadyl-methylpicolinate complex with hypoglycemic activity in streptozotocin-induced diabetic rats

Author keywords

Diabetes; Oral administration; Organ distribution; Vanadyl complex; Vanadyl methylpicolinate

Indexed keywords


EID: 0031403443     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.23.113     Document Type: Article
Times cited : (106)

References (40)
  • 1
    • 0001940329 scopus 로고
    • ed. by Mertz, W., and Cornatzen, W.E., Marcel Dekker, New York
    • Hopkins, L.L., Jr., and Mohr, H.E. (1971): Newer Trace Elements in Nutrition, ed. by Mertz, W., and Cornatzen, W.E., Marcel Dekker, New York, pp. 195-213.
    • (1971) Newer Trace Elements in Nutrition , pp. 195-213
    • Hopkins Jr., L.L.1    Mohr, H.E.2
  • 2
    • 0018781564 scopus 로고
    • Vanadate - A new tool for biologists
    • Simons, T.J.B. (1979): Vanadate - A new tool for biologists. Nature, 281, 337-338.
    • (1979) Nature , vol.281 , pp. 337-338
    • Simons, T.J.B.1
  • 5
    • 0021287515 scopus 로고
    • Mechanisms of action of vanadium
    • Nechay, B.R. (1984): Mechanisms of action of vanadium. Annu. Rev. Pharmacol. Toxicol., 24, 501-524.
    • (1984) Annu. Rev. Pharmacol. Toxicol. , vol.24 , pp. 501-524
    • Nechay, B.R.1
  • 6
    • 0021991110 scopus 로고
    • Effect of vanadate on elevated blood glucose and depressed cardiac performance of diabetic rats
    • Heylinger, C.E., Tahiliani, A.G., and McNeill, J.H. (1985): Effect of vanadate on elevated blood glucose and depressed cardiac performance of diabetic rats. Science, 227, 1474-1477.
    • (1985) Science , vol.227 , pp. 1474-1477
    • Heylinger, C.E.1    Tahiliani, A.G.2    McNeill, J.H.3
  • 7
    • 0028630915 scopus 로고
    • Effect of vanadium treatment on the alterations of cardiac glycogen phosphorylase and phosphorylase kinase in streptozotocin-induced chronic diabetic rats
    • Liu, H., and McNeill, J.H (1994): Effect of vanadium treatment on the alterations of cardiac glycogen phosphorylase and phosphorylase kinase in streptozotocin-induced chronic diabetic rats. Can. J. Physiol. Pharmacol., 2, 1537-1543.
    • (1994) Can. J. Physiol. Pharmacol. , vol.2 , pp. 1537-1543
    • Liu, H.1    McNeill, J.H.2
  • 8
    • 0028123576 scopus 로고
    • Investigation into vanadate-induced potentiation of smooth muscle contractility in the rabbit isolated ileum
    • Candura, S.M., Manzo, L., Marraccini, P., Coccini, T., and Tonini, M. (1994): Investigation into vanadate-induced potentiation of smooth muscle contractility in the rabbit isolated ileum. Life Sci., 54, 237-244.
    • (1994) Life Sci. , vol.54 , pp. 237-244
    • Candura, S.M.1    Manzo, L.2    Marraccini, P.3    Coccini, T.4    Tonini, M.5
  • 9
    • 0028046703 scopus 로고
    • Vanadate treatment reverses gastrointestinal complications in the streptozotocin-diabetic rats
    • Oeztuerk, Y., Yildizoglu-Ari, N., Pekiner, C., Oezcelikay, A.T., and Altan, V.M. (1994): Vanadate treatment reverses gastrointestinal complications in the streptozotocin-diabetic rats. Gen. Pharmacol., 25, 1109-1114.
    • (1994) Gen. Pharmacol. , vol.25 , pp. 1109-1114
    • Oeztuerk, Y.1    Yildizoglu-Ari, N.2    Pekiner, C.3    Oezcelikay, A.T.4    Altan, V.M.5
  • 10
    • 0029095614 scopus 로고
    • Effects of vanadate on glucose metabolism in the lens of rats with streptozotocin-induced diabetes. Ketohexokinase and aldolase activities
    • Adachi, K., Endo, M., Nagata, M., and Tamai, A. (1995): Effects of vanadate on glucose metabolism in the lens of rats with streptozotocin-induced diabetes. Ketohexokinase and aldolase activities. Yonago Acta Med., 38, 117-124.
    • (1995) Yonago Acta Med. , vol.38 , pp. 117-124
    • Adachi, K.1    Endo, M.2    Nagata, M.3    Tamai, A.4
  • 11
    • 0025342047 scopus 로고
    • Effect of in vivo vanadate treatment on insulin receptor tyrosine kinase activity in partially pancreatectomized diabetic animals
    • Cordera, R., Andraghetti, G., DeFronzo, R.A., and Rossetti, L. (1990): Effect of in vivo vanadate treatment on insulin receptor tyrosine kinase activity in partially pancreatectomized diabetic animals. Endocrinology, 126, 2177-2183.
    • (1990) Endocrinology , vol.126 , pp. 2177-2183
    • Cordera, R.1    Andraghetti, G.2    DeFronzo, R.A.3    Rossetti, L.4
  • 12
    • 0024416087 scopus 로고
    • Pervanadate [peroxide(s) of vanadate] mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase
    • Fantus, I.G., Kadota, S., Deragon, G., Foster, B., and Posner, B. (1989): Pervanadate [peroxide(s) of vanadate] mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase. Biochemistry, 28, 8864-8871.
    • (1989) Biochemistry , vol.28 , pp. 8864-8871
    • Fantus, I.G.1    Kadota, S.2    Deragon, G.3    Foster, B.4    Posner, B.5
  • 13
    • 0022473923 scopus 로고
    • The insulin-like effect of sodium vanadate on adipocyte glucose transport is mediated at a post insulin-receptor level
    • Green, A. (1986): The insulin-like effect of sodium vanadate on adipocyte glucose transport is mediated at a post insulin-receptor level. Biochem. J., 238, 663-669.
    • (1986) Biochem. J. , vol.238 , pp. 663-669
    • Green, A.1
  • 15
    • 0019152613 scopus 로고
    • Insulin-like stimulation of glucose oxidation in rat adipocytes by vanadyl (VI) ions
    • Schechter, Y., and Karlish, S.J.D. (1980): Insulin-like stimulation of glucose oxidation in rat adipocytes by vanadyl (VI) ions. Nature, 284, 556-558.
    • (1980) Nature , vol.284 , pp. 556-558
    • Schechter, Y.1    Karlish, S.J.D.2
  • 17
    • 0020564633 scopus 로고
    • Insulin-like effect of vanadate on adipocyte glycogen synthase and on phosphorylation of 95,000 dalton subunit of insulin receptor
    • Tamura, S., Brown, T.A., Dubler, R.E., and Larner, J. (1984): Insulin-like effect of vanadate on adipocyte glycogen synthase and on phosphorylation of 95,000 dalton subunit of insulin receptor. Biochem. Biophys. Res. Commun., 113, 80-86.
    • (1984) Biochem. Biophys. Res. Commun. , vol.113 , pp. 80-86
    • Tamura, S.1    Brown, T.A.2    Dubler, R.E.3    Larner, J.4
  • 18
    • 0029115108 scopus 로고
    • The role of vanadium in the management of diabetes
    • Brichard, S.M., and Henquin, J.C. (1995): The role of vanadium in the management of diabetes. Trends Pharmacol. Sci., 16, 265-270.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 265-270
    • Brichard, S.M.1    Henquin, J.C.2
  • 19
    • 0025060803 scopus 로고
    • Insulin-mimetic effects of vanadate
    • Shechter, Y. (1990): Insulin-mimetic effects of vanadate. Diabetes, 39, 1-5.
    • (1990) Diabetes , vol.39 , pp. 1-5
    • Shechter, Y.1
  • 20
    • 0023219921 scopus 로고
    • Oral administration of vanadate normalizes blood glucose levels in streptozotocin-treated rats
    • Meyerovitch, J., Farfel, Z., Sock, J., and Shechter, Y. (1987): Oral administration of vanadate normalizes blood glucose levels in streptozotocin-treated rats. J. Biol. Chem., 262, 6658-6662.
    • (1987) J. Biol. Chem. , vol.262 , pp. 6658-6662
    • Meyerovitch, J.1    Farfel, Z.2    Sock, J.3    Shechter, Y.4
  • 22
    • 0025028209 scopus 로고
    • Insulin-like effect of vanadyl ion on streptozotocin-induced diabetic rats
    • Sakurai, H., Tsuchiya, K., Nukatsuka, M., Sofue, M., and Kawada, J. (1990): Insulin-like effect of vanadyl ion on streptozotocin-induced diabetic rats. J. Endocrinol., 126, 451-459.
    • (1990) J. Endocrinol. , vol.126 , pp. 451-459
    • Sakurai, H.1    Tsuchiya, K.2    Nukatsuka, M.3    Sofue, M.4    Kawada, J.5
  • 24
    • 0026642054 scopus 로고
    • Bis(maltolato)-oxovanadium (IV) is a potent insulin mimic
    • McNeill, J.H., Yuen, V.G., Hoveyda, H.R., and Orvig, C. (1992): Bis(maltolato)-oxovanadium (IV) is a potent insulin mimic. J. Med. Chem., 35, 1489-1491.
    • (1992) J. Med. Chem. , vol.35 , pp. 1489-1491
    • McNeill, J.H.1    Yuen, V.G.2    Hoveyda, H.R.3    Orvig, C.4
  • 25
    • 0028288266 scopus 로고
    • A new orally active insulin-mimetic vanadyl complex: Bis(pyrrolidine-N-carbodithioato)oxovanadium (IV)
    • Watanabe, H., Nakai, M., Komazawa, K., and Sakurai, H. (1994): A new orally active insulin-mimetic vanadyl complex: Bis(pyrrolidine-N-carbodithioato)oxovanadium (IV). J. Med. Chem., 37, 876-877.
    • (1994) J. Med. Chem. , vol.37 , pp. 876-877
    • Watanabe, H.1    Nakai, M.2    Komazawa, K.3    Sakurai, H.4
  • 26
    • 0028882682 scopus 로고
    • Orally active and long-term acting insulin-mimetic vanadyl complex: Bis(picolinato)oxovanadium (IV)
    • Sakurai, H., Fujii, K., Watanabe, H., and Tamura. H. (1995): Orally active and long-term acting insulin-mimetic vanadyl complex: Bis(picolinato)oxovanadium (IV). Biochem. Biophys. Res. Commun., 214, 1095-1101.
    • (1995) Biochem. Biophys. Res. Commun. , vol.214 , pp. 1095-1101
    • Sakurai, H.1    Fujii, K.2    Watanabe, H.3    Tamura, H.4
  • 28
    • 0029072573 scopus 로고
    • Mechanism on insulin-like action of vanadyl sulfate: Studies on interaction between rat adipocytes and vanadium compounds
    • Nakai, M., Watanabe, H., Fujiwara, C., Kakegawa, H., Satoh, T., Takada, J., Matsushita, R., and Sakurai, H. (1995): Mechanism on insulin-like action of vanadyl sulfate: Studies on interaction between rat adipocytes and vanadium compounds. Biol. Pharm. Bull., 18, 719-725.
    • (1995) Biol. Pharm. Bull. , vol.18 , pp. 719-725
    • Nakai, M.1    Watanabe, H.2    Fujiwara, C.3    Kakegawa, H.4    Satoh, T.5    Takada, J.6    Matsushita, R.7    Sakurai, H.8
  • 29
    • 0018341167 scopus 로고
    • Activation of adenylate cyclase by vanadate
    • Schwabe, U., Puchstein, C., Hannemann, H., and Sochtig, E. (1979): Activation of adenylate cyclase by vanadate. Nature, 277, 143-145.
    • (1979) Nature , vol.277 , pp. 143-145
    • Schwabe, U.1    Puchstein, C.2    Hannemann, H.3    Sochtig, E.4
  • 30
    • 0028211343 scopus 로고
    • Synergistic activation of tyrosine phosphorylation by o-vanadate plus calcium ionophore A23187 or aromatic 1,2-diols
    • Huckle, W.H., and Earp, H.S. (1994): Synergistic activation of tyrosine phosphorylation by o-vanadate plus calcium ionophore A23187 or aromatic 1,2-diols. Biochemistry, 33, 1518-1525.
    • (1994) Biochemistry , vol.33 , pp. 1518-1525
    • Huckle, W.H.1    Earp, H.S.2
  • 31
    • 0028364232 scopus 로고
    • Vanadium activates or inhibits receptor and non-receptor protein tyrosine kinases in cell-free experiments, depending on its oxidation state
    • Elberg, G., Li, J., and Shechter, Y. (1994): Vanadium activates or inhibits receptor and non-receptor protein tyrosine kinases in cell-free experiments, depending on its oxidation state. J. Biol. Chem., 269, 9521-9527.
    • (1994) J. Biol. Chem. , vol.269 , pp. 9521-9527
    • Elberg, G.1    Li, J.2    Shechter, Y.3
  • 32
    • 0028913706 scopus 로고
    • Regulation of cyclic AMP phosphodiesterase activity by particulate protein tyrosine kinase and phosphotyrosine phosphatase activities sensitive to sodium orthovanadate
    • Ueki, H., Yamasaki, Y., Higo, K., Motoyashiki, T., Kawabata, H., and Morita, T. (1995): Regulation of cyclic AMP phosphodiesterase activity by particulate protein tyrosine kinase and phosphotyrosine phosphatase activities sensitive to sodium orthovanadate. Biol. Pharm. Bull., 18, 214-218.
    • (1995) Biol. Pharm. Bull. , vol.18 , pp. 214-218
    • Ueki, H.1    Yamasaki, Y.2    Higo, K.3    Motoyashiki, T.4    Kawabata, H.5    Morita, T.6
  • 34
    • 0028000395 scopus 로고
    • Effect of vanadium compounds on calmodulin activity in experimental diabetes in rats
    • Aktan, F., and Nebioglu, S. (1994): Effect of vanadium compounds on calmodulin activity in experimental diabetes in rats. Can. J. Physiol. Pharmacol., 72, 753-758.
    • (1994) Can. J. Physiol. Pharmacol. , vol.72 , pp. 753-758
    • Aktan, F.1    Nebioglu, S.2
  • 35
    • 0024580328 scopus 로고
    • The insulin-mimetic effect of vanadate is not correlated with insulin receptor tyrosine kinase activity nor phosphorylation in mouse diaphragm in vivo
    • Strout, H.V., Vicario, P.P., Saperstein, R., and Slater, E.E. (1989): The insulin-mimetic effect of vanadate is not correlated with insulin receptor tyrosine kinase activity nor phosphorylation in mouse diaphragm in vivo. Endocrinology, 124, 1918-1924.
    • (1989) Endocrinology , vol.124 , pp. 1918-1924
    • Strout, H.V.1    Vicario, P.P.2    Saperstein, R.3    Slater, E.E.4
  • 36
    • 77957010062 scopus 로고
    • Fractionation of cell components of animal tissues
    • Hogeboom, G. (1955): Fractionation of cell components of animal tissues. Methods Enzymol., 1, 16-19.
    • (1955) Methods Enzymol. , vol.1 , pp. 16-19
    • Hogeboom, G.1
  • 38
    • 0025694969 scopus 로고
    • Vanadate augments insulin binding and prolongs insulin action in rat adipocytes
    • Fantus, I.G., Ahmad, F., and Deragon, G. (1990): Vanadate augments insulin binding and prolongs insulin action in rat adipocytes. Endocrinology, 127, 2716-2725.
    • (1990) Endocrinology , vol.127 , pp. 2716-2725
    • Fantus, I.G.1    Ahmad, F.2    Deragon, G.3
  • 39
    • 0026708276 scopus 로고
    • Hydrophobic carriers of vanadyl ions augment the insulinomimetic actions of vanadyl ions in rat adipocytes
    • Shechter, Y., Shisheva, A., Lazar, R., Libman, J., and Shanzer, A. (1992): Hydrophobic carriers of vanadyl ions augment the insulinomimetic actions of vanadyl ions in rat adipocytes. Biochemistry, 31, 2063-2068.
    • (1992) Biochemistry , vol.31 , pp. 2063-2068
    • Shechter, Y.1    Shisheva, A.2    Lazar, R.3    Libman, J.4    Shanzer, A.5
  • 40
    • 0003925953 scopus 로고
    • ed. by Sigel, H., Marcel Dekker, New York
    • Heydorn, K. (1983): Metal Ions in Biological Systems, Vol. 16, ed. by Sigel, H., Marcel Dekker, New York, pp. 123-138.
    • (1983) Metal Ions in Biological Systems , vol.16 , pp. 123-138
    • Heydorn, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.