The luminal Na+/H+ exchanger NHE3 activity is regulated by NHE3 protein trafficking;Régulation de l'activité de l'échangeur Na+/H+ apical NHE3 par trafic intracellulaire de la protéine

Nephrologie

Volumn 23, Issue 5, 2002, Pages 219-224

  Du Cheyron, D ^a   Paillard, M ^a   Poggioli, Josiane ^a  

^a INSERM   (France)

Author keywords

Actin; Angiotensin II; Intracellular traffic; Na+H+ exchanger; NHE3

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; ANGIOTENSIN; BICARBONATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; EZRIN; MEMBRANE PROTEIN; PARATHYROID HORMONE; PROTEIN KINASE C; PROTON; SODIUM CHLORIDE; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN 3;

ARTICLE; CYTOSKELETON; ELECTROLYTE BALANCE; ENZYME MECHANISM; EXOCYTOSIS; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE ABSORPTION; POLYMERIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; PROTON SODIUM EXCHANGE;

ANIMALS; CYTOSKELETON; HUMANS; KIDNEY TUBULES; MODELS, BIOLOGICAL; PROTEIN TRANSPORT; SODIUM-HYDROGEN ANTIPORTER;

EID: 0036345235     PISSN: 02504960     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. - cotransporter
2. + exchanger
3. Role of microtubules in the rapid regulation of renal phosphate transport in response to acute alterations in dietary phosphate content
4. Vasopressin increases water permeability of kidney collecting duct by inducing translocation od aquaporin-CD water channels to plasme membrane
5. + reabsorption in A6 cells
6. Role of microfilaments in maintenance of proximal tubule structural and functional integrity
7. Association of the epithelial sodium cannel with Apx and a-spectrin in A6 epithelial cells
8. F-actin network may regulate a Cl- channel in renal proximal tubule cells
9. Involvement of actin cytoskeleton in modulation of apical K channel activity in rat collecting duct
10. - cotransport by forkolin and vasopressin in mouse kidney cultured thick ascending limb cells
11. + channel regulation
12. + exchanger isoform NHE3 in the proximal tubule
13. Active (9.6S) and inactive (21S) oligomers of NHE3 in microdomains of the renal brush border
14. Monoclonal antibodies for high-resolution localization of NHE3 in adult and neonatal rat kidney
15. + exchanger NHE3 isoform is regulated by the phosphatidyl 3-kinase pathway
16. + exchanger 3 accumulates and is functional in recycling endosomes
17. Signal complex regulation of renal transport proteins: NHERF and regulation of nNHE3 by PKA
18. Kidney cortex cells derived from SV40 transgenic mice retain intrinsic properties of polarized proximal tubule cells
19. + exchanger isoform NHE3 is regulated by the actin cytoskeleton
20. Rho GTPases and the actin cytoskeleton
21. + exchanger NHE3
22. NHE3 activity and trafficking depend on the state of actin organization in proximal tubule
23. + exchange in renal brush border vesicles
24. Dual mechanisms of regulation of Na/H exchanger NHE-3 by parathyroid hormone in rat kidney
25. Acute regulation of NHE3 by protein kinase A requires a multiprtein signal complex
26. NHERF associations with sodium-hydrogen exchanger isoform 3 (NHE3) and ezrin are essential for cAMP-mediated phosphorylation and inhibition of NHE3
27. + exchange in OK cells
28. + exchanger NHE3 by parathyroid hormone via NHE3 phosphorylation and dynamin-dependent endocytosis
29. Dopamine acutely stimulates Na/H exchanger (NHE3) endocytosis via clathrin-coated vesicles: Dependance on protein kinase A-mediated NHE3 phosphorylation
30. Sustained hypersensitivity to angiotensin II and its mechanism in mice lacking the subtype-2 (AT2) angiotensin receptor
31. Angiotensin II receptors
32. Transgenic models of angiotensin receptor subtype function in the cardiovascular system
33. Intrarenal production of angiotensin II
34. Selective Inhibition of protein kinase C isozymes by the indolocarbazol Gö 6976
35. Acid incubation causes exocytic insertion of NHE3 in OKP cells
36. B receptor activation causes exocytotic insertion of NHE3 in OKP cells
37. + transporters in kidneys of rats with ischemia-induced acute renal failure
38. + exchanger isoform NHE3 in proximal tubules induced by acute and chronic hypertension
39. Differential regulation of rat glomerular and proximal tubular renin mRNA following uninephrectomy
40. Renal renin-angiotensin system in diabetes: Functionnal, immunohistochemical, and molecular biological correlations
41. Regulation of proximal tubule sodium/hydrogen antiporter with chronic volume contraction
42. Rat proximal NHE3 adapts to chronic acid-base disorders but not to chronic changes in dietary NaCl intake