Acute regulation of NHE3 by protein kinase A requires a multiprotein signal complex

Kidney International

Volumn 60, Issue 2, 2001, Pages 450-454

  Weinman, Edward J ^a   Steplock, Deborah ^a   Shenolikar, Shirish ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Cell signaling; Ezrin; PDZ proteins; Proximal tubule; Renal electrolyte transport; Sodium hydrogen exchanger

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTEIN ANTIBODY; REGULATOR PROTEIN; SODIUM HYDROGEN EXCHANGER REGULATORY FACTOR 3; SODIUM PROTON EXCHANGE PROTEIN 3; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; CELL MEMBRANE; CONFERENCE PAPER; EPITHELIUM CELL; FIBROBLAST; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE ABSORPTION; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTON SODIUM EXCHANGE; SIGNAL TRANSDUCTION;

EID: 0034921559     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.060002450.x     Document Type: Article

References (30)

1. + exchanger in rabbit kidney brush-border membranes
2. + exchanger
3. + exchanger
4. + exchanger and its regulation by CAMP dependent protein kinase
5. + exchanger requires a dissociable phosphoprotein co-factor
6. + exchanger
7. + exchanger, NHE3, requires an associated regulatory protein
8. Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ERM family
9. Assembly of signaling complexes by NHERF family of PDZ-containing proteins
10. The role of NHERF and E3KARP in the cAMP-mediated inhibition of NHE3 cAMP-mediated inhibition of NHE3
11. + exchangers
12. Signal-complex regulation of renal transport proteins: NHERF and the regulation of NHE3 by PKA
13. + exchanger 3 (NHE3) is dependent on the presence but not the phosphorylation of NHERF
14. NHERF association with ezrin is essential for cAMP-mediated phosphorylation and inhibition of sodium-hydrogen exchanger isoform 3
15. + exchanger regulatory factor
16. Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)
17. A PDZ-interacting domain in CFTR is an apical membrane polarization signal
18. The B1 subunit of the H+ATPase is a PDZ-domain binding protein: Colocalization with NHE-RF in renal B-intercalated cells
19. 2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na/H exchanger regulatory factor family of PDZ proteins
20. Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity
21. 2-adrenergic receptor
22. Yes-associated protein 65 localizes p62 (c-Yes) to the apical compartment of airway epithelia by association with EBP50
23. The human testis determining factor SRY binds a nuclear factor containing PDZ protein interaction domains
24. + exchanger regulatory factor
25. Differential renal distribution of NHERF isoforms and their co-localization with NHE3. Ezrin, and ROMK
26. Regulation of the Na/H exchanger regulatory factor (NHE-RF) in OK cells
27. + exchange
28. Evidence for ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) self-association through PDZ-PDZ interactions
29. Visual transduction in Drosophila
30. N-terminal PDZ domain is required for NHERF dimerization