메뉴 건너뛰기




Volumn 26, Issue 4, 2002, Pages 36-58

Alteration in dissolution characteristics of gelatin-containing formulations: A review of the problem, test methods, and solutions

Author keywords

[No Author keywords available]

Indexed keywords

DISSOLUTION; PROBLEM SOLVING; PROTEINS;

EID: 0036334903     PISSN: 15342131     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (76)

References (91)
  • 1
  • 6
    • 0030001970 scopus 로고    scopus 로고
    • Physical-mechanical properties of film-coated soft gelatin capsules
    • (1996) Int. J. Pharm. , vol.127 , Issue.17 , pp. 203-211
    • Felton, L.A.1
  • 7
    • 0028935365 scopus 로고
    • Physical and enteric properties of soft gelatin capsules coated with eudragit L30 D-55
    • (1995) Int. J. Pharm. , vol.113 , Issue.2 , pp. 17-24
    • Felton, L.A.1
  • 13
    • 0026327071 scopus 로고
    • Concentration of cross-linking agent as a tool for the control of release and swelling properties of gelatin microspheres
    • (1991) J. Pharm. Bel. , vol.46 , pp. 381-388
    • Vandelli, M.A.1
  • 14
    • 0035857705 scopus 로고    scopus 로고
    • Gelatin microspheres cross-linked with D,L-Glyceraldehyde as a potential drug delivery system: Preparation, characterisation, in vitro and in vivo studies
    • (2001) Int. J. Pharm. , vol.215 , pp. 175-184
    • Vandelli, M.A.1
  • 15
  • 21
    • 0020818352 scopus 로고
    • Severe anaphylactoid reactions after infusion of modified gelatin solution
    • (1983) Therapie , vol.38 , pp. 539-546
    • Blanloeil, Y.1
  • 28
    • 0021315615 scopus 로고
    • Effects of short-term moderate storage stress on the disintegration and dissolution of four types of compressed tablets
    • (1984) Pharm. Acta. Helv. , vol.59 , Issue.5-6 , pp. 149-153
    • Ondari, C.O.1
  • 31
    • 0025910942 scopus 로고
    • The effect of pancreatin on the dissolution performance of gelatin-coated tablets exposed to high humidity conditions
    • (1991) Pharm. Res. , vol.8 , Issue.3 , pp. 412-414
    • Dahl, T.C.1    Sue, I.L.T.2    Yum, A.3
  • 37
    • 0017580994 scopus 로고
    • The shelf life of some antibiotic preparations stored under tropical conditions
    • (1977) Pharmazie , vol.32 , pp. 101-104
    • York, P.1
  • 38
    • 0022491678 scopus 로고
    • Investigation of drug biopharmaceutical stability: Application to capsules of tetracycline hydrochloride, Part 2: In vivo study
    • (1986) S.T.P. Pharma. , vol.2 , pp. 630-635
    • Mohamad, H.1
  • 42
    • 0027180263 scopus 로고
    • The dissolution and bioavailability of etodolac from capsules exposed to conditions of high relative humidity and temperatures
    • (1993) Pharm. Res. , vol.10 , Issue.9 , pp. 1295-1300
    • Dey, M.1
  • 46
    • 0031847969 scopus 로고    scopus 로고
    • The effects of cross-linking on the in vivo disintegration of hard gelatin capsules
    • (1998) Pharm. Res. , vol.15 , Issue.5 , pp. 1026-1030
    • Brown, J.1
  • 47
    • 0021473317 scopus 로고
    • Decrease in the rate of capsule dissolution due to formaldehyde from polysorbate 80 autooxidation
    • (1984) J. Pharm. Sci. , vol.73 , Issue.8 , pp. 1186-1187
    • Chafetz, L.1
  • 50
    • 0017383215 scopus 로고
    • The effects of storage upon in vitro and in vivo characteristics of soft gelatin capsules containing digoxin
    • (1977) J. Pharm. Pharmacol. , vol.29 , pp. 576-578
    • Johnson, D.F.1
  • 52
    • 0022972888 scopus 로고
    • Investigation of drug biopharmaceutical stability, part 3: Study of ampicillin trihydrate capsules (in vitro-in vivo investigation)
    • (1986) S.T.P. Pharma. , vol.2 , pp. 912-917
    • Mohamad, H.1
  • 55
    • 0034131060 scopus 로고    scopus 로고
    • Bioequivalence study of stressed and unstressed hard gelatin capsules using amoxycillin as a drug marker and gamma scintigraphy to confirm time and GI location of in vivo capsules rupture
    • (2000) Pharm. Res. , vol.17 , Issue.5 , pp. 572-582
    • Digenis, G.A.1
  • 56
    • 0033795359 scopus 로고    scopus 로고
    • The effect of gelatin cross-linking on the bioequivalence of hard and soft gelatin acetaminophen capsules
    • (2000) Pharm. Res. , vol.17 , Issue.8 , pp. 962-966
    • Meyer, M.C.1
  • 57
    • 2142734555 scopus 로고    scopus 로고
    • Physical tests and determinations
    • (1999) Pharm. Forum , vol.25 , pp. 7516
  • 60
    • 0035158246 scopus 로고    scopus 로고
    • Cross-linking studies in gelatin capsules treated with formaldehyde and exposed to elevated temperature and humidity
    • (2001) J. Pharm. Sci. , vol.90 , Issue.1 , pp. 78-88
    • Ofner C.M. III1
  • 61
    • 0030767561 scopus 로고    scopus 로고
    • Determination of extent of formaldehyde-induced cross-linking in hard gelatin capsules by near-infrared spectrophotometry
    • (1997) Pharm. Res. , vol.14 , Issue.8 , pp. 1046-1050
    • Gold, T.B.1
  • 62
    • 0031836002 scopus 로고    scopus 로고
    • Detection of formaldehyde-induced cross-linking in soft elastic gelatin capsules using near-infrared spectrometry
    • (1998) Pharm. Dev. Technol. , vol.3 , Issue.2 , pp. 209-214
    • Gold, T.B.1
  • 65
    • 0002238387 scopus 로고
    • Rayon: Source of furfural - A reactive aldehyde capable of insolublizing gelatin capsules
    • (1993) Pharm. Technol. , vol.17 , pp. 78-80
    • Schwier, J.R.1
  • 69
    • 2142672751 scopus 로고
    • Effect of rayon coiler on the dissolution stability of hard-shell gelatin capsules
    • (1993) Pharm. Technol. , vol.17 , pp. 76-83
    • Hartauer, K.J.1
  • 71
    • 0027993485 scopus 로고
    • Effect of storage temperature on the physicochemical properties of soft gelatin capsule shells
    • (1994) Chem. Pharm. Bull. , vol.42 , pp. 1496-1500
    • Hakata, T.1
  • 72
    • 0028356331 scopus 로고
    • Effect of formaldehyde on the physicochemical properties of soft gelatin capsule shells
    • (1994) Chem. Pharm. Bull. , vol.42 , pp. 1138-1142
    • Hakata, T.1
  • 74
    • 0017293228 scopus 로고
    • Investigation and evaluation of the utilization of gelatin treated with ionizing radiation in the pharmaceutical industry
    • (1976) Gyogyszereszet , vol.20 , Issue.1 , pp. 5-7
    • Lengyel, J.1
  • 80
    • 0026614994 scopus 로고
    • The determination of ε-amino group in soluble and poorly soluble proteinaceous materials by a spectrophotometric method using trinitrobenzenesulfonic acid
    • (1992) Anal. Biochem. , vol.207 , pp. 129-133
    • Bubnis, W.A.1    Ofner C.M. III2
  • 81
    • 0030445829 scopus 로고    scopus 로고
    • Chemical and swelling evaluations of amino group cross-linking in gelatin and modified gelatin matrices
    • (1996) Pharm. Res. , vol.13 , Issue.12 , pp. 1821-1827
    • Ofner C.M. III1    Bubnis, W.A.2
  • 82
    • 0343193250 scopus 로고    scopus 로고
    • Intrinsic fluorescence investigation on the change in conformation of cross-linked gelatin gel during volume phase transition
    • (2000) Polymer , vol.41 , pp. 7589-7592
    • Liu, W.G.1
  • 89
    • 0020662990 scopus 로고
    • Phenytoin I: In vitro-in vivo correlation for 100 mg phenytoin sodium capsules
    • (1983) J. Pharm. Sci. , vol.72 , Issue.3 , pp. 306-308
    • Shah, V.P.1
  • 91
    • 0021354002 scopus 로고
    • Soft gelatin capsules III: An accelerated method for evaluating the dissolution stability of various gel formulations
    • (1984) Drug Dev. Ind. Pharm. , vol.10 , Issue.2 , pp. 275-287
    • Hom, F.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.