Genes of de novo pyrimidine biosynthesis from the hyperthermoacidophilic crenarchaeote Sulfolobus acidocaldarius: Novel organization in a bipolar operon

Journal of Bacteriology

Volumn 184, Issue 16, 2002, Pages 4430-4441

  Thia Toong, Thia Lin ^a   Roovers, Martine ^a   Durbecq, Virginie ^a   Gigot, Daniel ^a   Glansdorff, Nicolas ^a   Charlier, Daniel ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CONTIG; MESSENGER RNA; PURINE; PYRIMIDINE; REGULATOR PROTEIN; RIBOSOME RNA; SPACER DNA; URACIL;

ARTICLE; BACTERIAL GENOME; BASE PAIRING; BIOSYNTHESIS; CISTRON; CODON; COMPARATIVE STUDY; CRENARCHAEOTA; GENE CLUSTER; GENE ORDER; GENE SEQUENCE; GENETIC CODE; GENETIC DISTANCE; GENETIC ORGANIZATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OPERON; PRIORITY JOURNAL; PROMOTER REGION; PYRBI GENE; PYRCD GENE; PYREF GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; STRAIN DIFFERENCE; SULFOLOBUS ACIDOCALDARIUS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ASPARTATE CARBAMOYLTRANSFERASE; BASE SEQUENCE; CLONING, MOLECULAR; CODON, TERMINATOR; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; OPERON; PROMOTER REGIONS (GENETICS); PYRIMIDINES; SULFOLOBUS ACIDOCALDARIUS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); CRENARCHAEOTA; PROKARYOTA; SULFOLOBUS; SULFOLOBUS ACIDOCALDARIUS; SULFOLOBUS SOLFATARICUS; SULFOLOBUS TOKODAII STR. 7; UNCULTURED ACTINOMYCETE;

EID: 0036334613     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.184.16.4430-4441.2002     Document Type: Article

References (61)

1. Sequence analysis and identification of the pyrKDbF operon from Lactococcus lactis including a novel gene, pyrK, involved in pyrimidine biosynthesis
2. Orientation of the transcription preinitiation complex in Archaea
3. Molecular recognition of pyr mRNA by the Bacillus subtilis attenuation regulatory protein PyrR
4. Sulfolobus: A new genus of sulfur-oxidizing bacteria living at low pH and high temperature
5. Mutational analysis of Escherichia coli PepA, a multifunctional DNA-binding aminopeptidase
6. Integration host factor (IHF) modulates the expression of the pyrimidine-specific promoter of the carAB operons of Escherichia coli K12 and Salmonella typhimurium LT2
7. Cloning and identification of the Sulfolobus solfataricus lrp gene encoding an archaeal homologue of the eubacterial leucine-responsive global transcriptional regulator Lrp
8. A reagent for the single-step simultaneous isolation of RNA. DNA and proteins from cells and tissue samples
9. Cis-acting signals controlling translation initiation in the thermophilic archaeon Sulfolobus solfataricus
10. Prolonged incubation in calcium chloride improves the competence of E. coli cells
11. Aspartate carbamoyltransferase from the thermoacidophilic archaeon Sulfolobus acidocaldarius
12. Structure and organisation of the pyrimidine biosynthesis pathway genes in Lactobacillus plantarum: A PCR strategy for sequencing without cloning
13. Purification and characterization of Sa-Lrp, a DNA-binding protein from the extreme thermoacidophilic archaeon Sulfolobus acidocaldarius homologous to the bacterial global transcription regulator Lrp
14. Phylogenetic analysis and classification of dihydroorotases: A complex history for a complex enzyme
15. Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum
16. Chromosomal marker exchange in the thermophilic archaeon Sulfolobus acidocaldarius: Physiological and cellular aspects
17. The pyrimidine biosynthesis operon of the thermophile Bacillus caldolyticus includes genes for uracil phosphoribosyltransferase and uracil permease
18. Molecular characterization of pyrimidine biosynthesis genes from the hyperthermophile Bacillus caldolyticus
19. Topography of cotransducible arginine mutations in Escherichia coli K12
20. Genetic studies on the pyrimidine paradigm in prokaryotes: New insights in regulatory mechanisms
21. Selective stimulation of translation of leaderless mRNA by initiation factor 2: Evolutionary implications for translation
22. Genetic fidelity under harsh conditions: Analysis of spontaneous mutation in the thermoacidophilic archaeon Sulfolobus acidocaldarius
23. Sulfolobus acidocaldarius synthesizes UMP via a standard de novo pathway: Results of a biochemical-genetic study
24. Isolate B12, which harbours a virus-like element, represents a new species of the archaebacterial genus Sulfolobus. Sulfolobus shibatae, sp. nov
25. Elements of an archaeal promoter defined by mutational analysis
26. Regulation of carAB expression in Escherichia coli occurs in part through UTP-sensitive reiterative transcription
27. Spontaneous mutation in a thermoacidophilic archaeon: Evaluation of genetic and physiological factors
28. Eubacterial, archaebacterial and eukaryotic genes that encode leaderless mRNA
29. Evolutionary and functional families of dihydroorotate dehydrogenases
30. Identification of a novel gene of pyrimidine nucleotide biosynthesis, pyrDII, that is required for dihydroorotate dehydrogenase activity in Bacillus subtilis
31. Complete genome sequence of an aerobic hyperthermophilic crenarchaeon, Aeropyrum pernix K1
32. Complete genome sequence of an aerobic thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain 7
33. pyrH-encoded UMP-kinase directly participates in pyrimidine-specific modulation of promoter activity in Escherichia coli
34. The evolutionary history of carbamoyltransferases: A complex set of paralogous genes was already present in the last universal common ancestor
35. Ammonia-dependent synthesis and metabolic channeling of carbamoyl phosphate in the hyperthermophilic archaeon Pyrococcus furiosus
36. Generation of auxotrophic mutants of Enterococcus faecalis
37. Protein measurements with folin phenol reagent
38. The carB gene encoding the large subunit of carbamoylphosphate synthetase from Lactococcus lactis is transcribed monocistronically
39. The pyrimidine operon pyrRPB-carA from Lactococcus lactis
40. Metabolic channeling of carbamoyl phosphate, a thermolabile intermediate: Evidence for physical interaction between carbamate kinase-like carbamoyl phosphate synthetase and ornithine carbamoyltransferase from the hyperthermophile Pyrococcus furiosus
41. New M13 vectors for cloning
42. Biosynthesis and conversion of pyrimidines
43. Channeling of carbamoyl phosphate to the pyrimidine and arginine biosynthetic pathways in the deep sea hyperthermophilic archaeon Pyrococcus abyssi
44. Cloning, expression, and structure analysis of carbamate kinase-like carbamoyl phosphate synthetase from Pyrococcus abyssi
45. Functional organization and nucleotide sequence of the Bacillus subtilis pyrimidine biosynthetic operon
46. Characterization of intragenic recombination in a hyperthermophilic archaeon via conjugational DNA exchange
47. DNA sequencing with chain-terminating inhibitors
48. UV stimulation of chromosomal marker exchange in Sulfolobus acidocaldarius: Implications for DNA repair, conjugation and homologous recombination at extremely high temperatures
49. Aspartate transcarbamoylase genes of Pseudomonas putida: Requirement for an inactive dihydroorotase for assembly into the dodecameric holoenzyme
50. Completing the sequence of the Sulfolobus solfataricus P2 genome
51. Organizational characteristics and information content of an archaeal genome: 156 kb of sequence from Sulfolobus solfataricus P2
52. The complete genome of the crenarchaeon Sulfolobus solfataricus P2
53. Regulation of the Bacillus subtilis pyrimidine biosynthetic operon by transcriptional attenuation: Control of gene expression by a mRNA-binding protein
54. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
55. Regulation of the Bacillus subtilis pyrimidine biosynthetic (pyr) gene cluster by an autogenous transcriptional attenuation mechanism
56. Molecular physiology and carbamoylation under extreme conditions: What can we learn from extreme thermophilic microorganisms?
57. Structure and expression of a pyrimidine gene cluster from the extreme thermophile Thermus strain ZO5
58. Genes encoding aspartate carbamoyltransferase of Thermus aquaticus ZO5 and Thermotoga maritima MSB8: Modes of expression in E. coli and properties of their products
59. The pUC plasmids, an M13mp7-derived system for insertional mutagenesis and sequencing with synthetic universal primers
60. The Sulfolobus-Caldariella group: Taxonomy on the basis of the structure of DNA-dependent RNA polymerases