Detection and cellular localisation of the synthetic soluble macromolecular drug carrier pHPMA

European Journal of Nuclear Medicine

Volumn 29, Issue 8, 2002, Pages 1055-1062

  Kissel, Maria ^a,b,c   Peschke, Peter ^a,b,c   Šubr, Vladimir ^a,b,c   Ulbrich, Karel ^a,b,c   Strunz, Anke M ^a,b,c   Kühnlein, Rainer ^a,b,c   Debus, Jürgen ^a,b,c   Friedrich, Eckhard ^a,b,c  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

^c Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

Biotin; Drug targeting; EPR effect; HPMA; Pharmacokinetic; Radiolabelled macromolecules

Indexed keywords

ALKALINE PHOSPHATASE; BIOTIN; DRUG CARRIER; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; PARAFORMALDEHYDE; PHOSPHATE; STREPTAVIDIN; COPOLYMER; N (2 HYDROXYPROPYL)METHACRYLAMIDE; ACRYLAMIDE DERIVATIVE; DIAGNOSTIC AGENT; ESTER; METHACRYLIC ACID DERIVATIVE; METHACRYLOYLGLYCYLGLYCINE 4 NITROPHENYL ESTER; METHACRYLOYLGLYCYLGLYCINE-4-NITROPHENYL ESTER; N-(2-HYDROXYPROPYL)METHACRYLAMIDE; RADIOACTIVE IODINE; RADIOPHARMACEUTICAL AGENT;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRUSH BORDER; CONTROLLED STUDY; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG SOLUBILITY; HISTOLOGY; KIDNEY DISTAL TUBULE; MACROMOLECULE; MALE; NONHUMAN; ORGAN DISTRIBUTION; PROSTATE ADENOCARCINOMA; RADIOACTIVITY; RAT; SCINTIGRAPHY; ANIMAL EXPERIMENT; BIOTINYLATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; DRUG ABSORPTION; DRUG ACCUMULATION; DRUG LABELING; DRUG TARGETING; KIDNEY TUBULE ABSORPTION; TUMOR; ADENOCARCINOMA; ANIMAL; CANCER TRANSPLANTATION; CELL CULTURE; COMPARATIVE STUDY; METABOLISM; PATHOLOGY; PROSTATE TUMOR; REFERENCE VALUE; SCINTISCANNING; SOLUBILITY; THIGH; TISSUE DISTRIBUTION; WHOLE BODY COUNTING;

ACRYLAMIDES; ADENOCARCINOMA; ANIMAL; BIOTIN; COMPARATIVE STUDY; DRUG CARRIERS; ESTERS; IODINE RADIOISOTOPES; MACROMOLECULAR SYSTEMS; MALE; METHACRYLATES; NEOPLASM TRANSPLANTATION; PROSTATIC NEOPLASMS; RADIOPHARMACEUTICALS; RATS; REFERENCE VALUES; SOLUBILITY; SUPPORT, NON-U.S. GOV'T; THIGH; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED; WHOLE-BODY COUNTING; ANIMALS; MACROMOLECULAR SUBSTANCES;

EID: 0036326798     PISSN: 03406997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-002-0835-0     Document Type: Article

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