In the cystathionine β-synthase knockout mouse, elevations in total plasma homocysteine increase tissue S-adenosylhomocysteine, but responses of S-adenosylmethionine and DNA methylation are tissue specific

Journal of Nutrition

Volumn 132, Issue 8, 2002, Pages 2157-2160

  Choumenkovitch, Silvina F ^a   Selhub, Jacob ^a   Bagley, Pamela J ^a   Maeda, Nobuyo ^a   Nadeau, Marie R ^a   Smith, Donald E ^a   Choi, Sang Woon ^a,b  

^a TUFTS UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Cystathionine synthase; DNA methylation; Mice; S adenosylhomocysteine; S adenosylmethionine

Indexed keywords

CYSTATHIONINE BETA SYNTHASE; GENOMIC DNA; HOMOCYSTEINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; BRAIN; CARBON METABOLISM; CONTROLLED STUDY; DNA METHYLATION; ENZYME DEFICIENCY; FEMALE; FOOD DEPRIVATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMOZYGOSITY; IN VITRO STUDY; KIDNEY; KNOCKOUT MOUSE; LIVER; MALE; MEASUREMENT; MOUSE; MOUSE STRAIN; NONHUMAN; REGULATORY MECHANISM; TISSUE SPECIFICITY;

ANIMALIA;

EID: 0036322745     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/132.8.2157     Document Type: Article

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