Characterization of a secreted Chlamydia protease

Cellular Microbiology

Volumn 4, Issue 7, 2002, Pages 411-424

  Shaw, Allan C ^a   Vandahl, Brian B ^a,b   Larsen, Martin R ^c   Roepstorff, Peter ^c   Gevaert, Kris ^d   Vandekerckhove, Joël ^d   Christiansen, Gunna ^a   Birkelund, Svend ^a,b  

^a AARHUS UNIVERSITY   (Denmark)

^b Science Park Aarhus ^*  (Denmark)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CHLAMYDIAL PROTEASOME LIKE ACTIVITY FACTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEINASE; PROTEOME; SULFUR 35; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIGEN PRESENTATION; ARTICLE; BACTERIAL GENOME; CELL LYSATE; CHLAMYDIA; CHLAMYDIA TRACHOMATIS; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; HOST CELL; HUMAN; HUMAN CELL; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN MOTIF; PROTEIN SECRETION; PROTEOMICS; TWO DIMENSIONAL GEL ELECTROPHORESIS;

AMINO ACID SEQUENCE; ANTIBODIES, BACTERIAL; BASE SEQUENCE; CELL LINE; CHLAMYDIA TRACHOMATIS; CHLAMYDOPHILA PNEUMONIAE; CLONING, MOLECULAR; DNA, BACTERIAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOPEPTIDASES; HELA CELLS; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEASE INHIBITORS; SPECIES SPECIFICITY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

BACTERIA (MICROORGANISMS); CHLAMYDIA; CHLAMYDIA TRACHOMATIS; CHLAMYDIAE; CHLAMYDOPHILA; CHLAMYDOPHILA PNEUMONIAE;

EID: 0036319528     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1462-5822.2002.00200.x     Document Type: Article

References (28)

1. Chemical Cross-Linking of Chlamydia trachomatis
2. Molecular biology of the Chlamydia pneumoniae surface
3. Chlamydia pneumoniae secretion of a protease-like activity factor for degrading host cell transcription factors is required for major histocompatibility complex antigen expression
4. Evidence for the secretion of Chlamydia trachomatis CopN by a type III secretion mechanism
5. Peptides adsorbed on reverse-phase chromatographic beads as targets for femtomolesequencing by post-source decay matrix assisted laser desorption ionization-reflectron time of flight mass spectrometry (MALDI-RETOF-MS)
6. The RFX complex is crucial for the constitutive and CIITA-mediated transactivation of MHC class I and beta2-microglobulin genes
7. Rapid micro-scale proteolysis of proteins for MALDI-MS peptide mapping using immobilized trypsin
8. Comparison of yeast cell protein solubilization procedures for two-dimensional electrophoresis
9. Type III secretion genes identify a putative virulence locus of Chlamydia
10. Type III protein secretion systems in bacterial pathogens of animals and plants
11. Mass spectrometric identification and microcharacterization of proteins from electrophoretic gels: Strategies and applications
12. Comparative genomes of Chlamydia pneumoniae and C. trachomatis
13. Interaction of chlamydiae and host cells in vitro
14. Activation of the MHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between Stat1 and USF-1
15. Analysis of the humoral immune response to Chlamydia outer membrane protein 2
16. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
17. The intracellular life of Chlamydia
18. Culture and isolation of Chlamydia trachomatis
19. Mapping and identification of interferon gamma-regulated HeLa cell proteins separated by immobilized pH gradient two-dimensional gel electrophoresis
20. Genetic differences in the Chlamydia trachomatis tryptophan synthase α-subunit can explain variations in serovar pathogenesis
21. Comparative proteome analysis of Chlamydia trachomatis serovar A, D and L2
22. Tsp: A tail-specific protease that selectively degrades proteins with nonpolar C termini
23. Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis
24. Secretion of predicted Inc proteins of Chlamydia pneumoniae by a heterologous type III machinery
25. Proteome analysis of Chlamydia pneumoniae elementary body
26. Chlamydia inhibits interferon gamma-inducible Major Histocompatibility Complex Class II expression by degradation of Upstream Stimulatory Factor 1
27. Degradation of transcription factor RFX5 during the inhibition of both constitutive and interferon gamma-inducible Major Histocompatibility Complex Class I expression in Chlamydia infected cells
28. Identification of a Chlamydial protease-like activity factor responsible for the degradation of host transcription factors