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Volumn 43, Issue 7, 2002, Pages 1035-1045

Inhibition of phosphatidylcholine synthesis via the phosphatidylethanolamine methylation pathway impairs incorporation of bulk lipids into VLDL in cultured rat hepatocytes

Author keywords

3 deazaadenosine; Apolipoprotein B; Bezafibrate

Indexed keywords

3 DEAZAADENOSINE; ADENOSYLHOMOCYSTEINASE; ANTILIPEMIC AGENT; APOLIPOPROTEIN B48; BEZAFIBRATE; HIGH DENSITY LIPOPROTEIN; METHIONINE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLETHANOLAMINE METHYLTRANSFERASE; SULFUR 35; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

EID: 0036317846     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1194/jlr.M100354-JLR200     Document Type: Article
Times cited : (33)

References (48)
  • 1
    • 0027531667 scopus 로고
    • Regulation of hepatic secretion of apolipoprotein B-containing lipoproteins: Information obtained from cultured liver cells
    • (1993) J. Lipid Res. , vol.34 , pp. 167-179
    • Dixon, J.L.1    Ginsberg, H.N.2
  • 8
    • 0023833533 scopus 로고
    • The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes
    • (1988) J. Biol. Chem. , vol.263 , pp. 2998-3004
    • Yao, Z.M.1    Vance, D.E.2
  • 10
    • 0030580422 scopus 로고    scopus 로고
    • The role of phosphatidylethanolamine methylation in the secretion of very low density lipoproteins by cultured rat hepatocytes: Rapid inhibition of phosphatidylethanolamine methylation by bezafibrate increases the density of apolipoprotein B48-containing lipoproteins
    • (1996) Biochim. Biophys. Acta , vol.1304 , pp. 21-31
    • Nishimaki-Mogami, T.1    Suzuki, K.2    Takahashi, A.3
  • 19
    • 0028919913 scopus 로고
    • Assembly of very low density lipoproteins in rat liver: A study of nascent particles recovered from the rough endoplasmic reticulum
    • (1995) J. Lipid Res. , vol.36 , pp. 395-406
    • Swift, L.L.1
  • 25
    • 0027436445 scopus 로고
    • Movement of apolipoprotein B into the lumen of microsomes from hepatocytes is disrupted in membranes enriched in phosphatidylmonomethylethanolamine
    • (1993) J. Biol. Chem. , vol.268 , pp. 25168-25175
    • Rusinol, A.E.1    Chan, E.Y.2    Vance, J.E.3
  • 27
    • 0029070632 scopus 로고
    • Inhibition of secretion of truncated apolipoproteins B by monomethylethanolamine is independent of the length of the apolipoprotein
    • (1995) J. Biol. Chem. , vol.270 , pp. 13318-13325
    • Rusinol, A.E.1    Vance, J.E.2
  • 34
    • 0022976403 scopus 로고
    • A deazaadenosine-insensitive methylation of phosphatidylethanolamine is involved in lipoprotein secretion
    • (1986) FEBS Lett. , vol.204 , pp. 243-246
    • Vance, J.E.1    Vance, D.E.2
  • 35
    • 0027973135 scopus 로고
    • A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins
    • (1994) J. Biol. Chem. , vol.269 , pp. 27494-27502
    • Rusinol, A.E.1    Cui, Z.2    Chen, M.H.3    Vance, J.E.4
  • 36
    • 0026329508 scopus 로고
    • Secretion of VLDL, but not HDL, by rat hepatocytes is inhibited by the ethanolamine analogue N-monomethylethanolamine
    • (1991) J. Lipid Res. , vol.32 , pp. 1971-1982
    • Vance, J.E.1
  • 40
    • 0029114541 scopus 로고
    • Nascent VLDL phospholipid composition is altered when phosphatidylcholine biosynthesis is inhibited: Evidence for a novel mechanism that regulates VLDL secretion
    • (1995) Biochim. Biophys. Acta , vol.1258 , pp. 159-168
    • Fast, D.G.1    Vance, D.E.2
  • 42
    • 0029610552 scopus 로고
    • Expression of phosphatidylethanolamine N-methyltransferase-2 in McArdle-RH7777 hepatoma cells inhibits the CDP-choline pathway for phosphatidylcholine biosynthesis via decreased gene expression of CTP: Phosphocholine cytidylyltransferase
    • (1995) Biochem. J. , vol.312 , pp. 939-945
    • Cui, Z.1    Houweling, M.2    Vance, D.E.3
  • 43
    • 0030044041 scopus 로고    scopus 로고
    • Expression of phosphatidylethanolamine N-methyltransferase-2 is markedly enhanced in long term choline-deficient rats
    • (1996) J. Biol. Chem. , vol.271 , pp. 2839-2843
    • Cui, Z.1    Vance, D.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.