Effect of GP120 on glutathione peroxidase activity in cortical cultures and the interaction with steroid hormones

Journal of Neurochemistry

Volumn 81, Issue 2, 2002, Pages 277-284

  Brooke, Sheila M ^a   McLaughlin, John R ^a   Cortopassi, Karen M ^a   Sapolsky, Robert M ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

Estrogen; Glucocorticoids; Glutathione peroxidase; gp120; Neurotoxicity; Reactive oxygen species

Indexed keywords

COAT PROTEIN; CORTICOSTEROID; ESTROGEN; GLUCOCORTICOID; GLUTATHIONE PEROXIDASE; GLYCOPROTEIN GP 120; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; STEROID HORMONE; SUPEROXIDE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL CULTURE; CELL LOSS; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; STRESS;

ANIMALS; CATALASE; CELL COUNT; CELLS, CULTURED; CEREBRAL CORTEX; CORTICOSTERONE; DRUG INTERACTIONS; ENZYME ACTIVATION; ESTROGENS; GENETIC VECTORS; GLUCOCORTICOIDS; GLUTATHIONE PEROXIDASE; HIV ENVELOPE PROTEIN GP120; HUMANS; HYDROGEN PEROXIDE; NEURONS; OXIDANTS; RATS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0036316965     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00825.x     Document Type: Article

References (53)

1. Rate and severity of HIV-associated dementia (HAD): Correlations with Gp41 and iNOS
2. Prenatal exposure to high levels of glucocorticoids increases the susceptibility of cerebellar granule cells to oxidative stress-induced cell death
3. Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury
4. The HIV-1 gp120 causes ultrastructural changes typical of apoptosis in the rat cerebral cortex
5. gp120, a human immunodeficiency virus-1 coat protein, augments excitotoxic hippocampal injury in perinatal rats
6. Effect of acute exposure to 3-nitropropionic acid on activities of endogenous antioxidants in the rat brain
7. Interleukin-1 alpha and vasoactive intestinal peptide: Enigmatic regulation of neuronal survival
8. The effects of steroid hormones in HIV-related neurotoxicity: A mini review
9. Endocrine modulation of the neurotoxicity of gp120: Implications for AIDS-related dementia complex
10. Energy dependency of glucocorticoid exacerbation of gp120 neurotoxicity
11. Quantification of neuron survival in monolayer cultures using an enzyme-linked immunosorbent assay approach, rather than by cell counting
12. Neuropathology of human immunodeficiency virus infection
13. Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils
14. Requirement for membrane lipid peroxidation in HIV-1 gp120-induced neuroblastoma cell death
15. Antioxidants and dipyridamole inhibit HIV-1 gp120-induced free radical-based oxidative damage to human monocytoid cells
16. Induction of Cu,Zn-superoxide dismutase after cortical contusion injury during hypothermia
17. Corticosteroids as adjunctive therapy for severe Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A double-blind, placebo-controlled trial
18. The neuropathogenesis of HIV-1 infection
19. Effects of footshock stress on superoxide dismutase and glutathione peroxidase enzyme activities and thiobarbituric acid reactive substances levels in the rat prefrontal cortex and striatum
20. The antioxidant enzymes glutathione peroxidase and catalase increase following traumatic brain injury in the rat
21. Astrocytes are the major source of nerve growth factor upregulation following traumatic brain injury in the rat
22. Reactive oxygen species and the central nervous system
23. Differential antioxidant enzyme activities and glutathione content between rat and rabbit conceptuses
24. Amplicon-based herpes simplex virus vectors
25. Herpes simplex virus vector system: Analysis of its in vivo and in vitro cytopathic effects
26. Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures
27. Mechanisms of estrogenic protection against gp120-induced neurotoxicity
28. Herpes simplex virus vectors overexpressing the glucose transporter gene protect against seizure-induced neuron loss
29. Hydrogen peroxide suppresses U937 cell death by two different mechanisms depending on its concentration
30. Neuronal injury associated with HIV-1: Approaches to treatment
31. Estrogen actions in the central nervous system
32. Glucocorticoids may alter antioxidant enzyme capacity in the brain: Kainic acid studies
33. Spectrum of human immunodeficiency virus-associated neocortical damage
34. Effects of recombinant superoxide dismutase on manganese superoxide dismutase gene expression in gerbil hippocampus after ischemia
35. Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration
36. Human immunodeficiency virus type I (HIV-1) infection of the nervous system: A review
37. Structure and function of the 5′-flanking sequence of the human cytosolic selenium-dependent glutathione peroxidase gene (hgpxl)
38. Effects of progesterone and estradiol benzoate on glutathione dependent antioxidant enzyme activities in the brain of female rats
39. Use of adjunctive corticosteroids in severe adult non-HIV Pneumocystis carinii pneumonia
40. Genetic and metabolic control of the mitochondrial transmembrane potential and reactive oxygen intermediate production in HIV disease
41. Regulatory antioxidant enzymes
42. The brain in AIDS: Central nervous system HIV-1 infection and AIDS dementia complex
43. Changes in antioxidant enzyme expression in response to hydrogen peroxide in rat astroglial cells
44. Neuroprotection with herpes simplex vectors expressing virally derived anti-apoptotic agents
45. Molecular and biological mechansims in the development of AIDS dementia complex (ADC)
46. Stress, glucocorticoids, and damage to the nervous system: The current state of confusion
47. Gene therapy using viral vectors for acute neurologic insults
48. Strategies of antioxidant defense
49. Catalase in astroglia-fich primary cultures from rat brain: Immunocytochemical localization and inactivation during the disposal of hydrogen peroxide
50. In vivo trapping of nitric oxide in the brain of neonatal rats treated with the HIV-1 envelope protein gp 120: Protective effects of alpha-phenyl-tert-butylnitrone
51. Differential induction of superoxide dismutase in core and penumbra regions after transient focal ischemia in the rat neocortex
52. Induction of ischemic tolerance and antioxidant activity by brief focal ischemia
53. Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture