Nigrostriatal lesion and dopamine agonists affect firing patterns of rodent entopeduncular nucleus neurons

Journal of Neurophysiology

Volumn 88, Issue 1, 2002, Pages 487-496

  Ruskin, David N ^a   Bergstrom, Debra A ^a   Walters, Judith R ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; DOPAMINE; DOPAMINE 1 RECEPTOR STIMULATING AGENT; DOPAMINE 2 RECEPTOR STIMULATING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; OXIDOPAMINE; QUINPIROLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BEHAVIOR; BRAIN INJURY; CELL ACTIVITY; CELL LOSS; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; ENTOPEDUNCULAR NUCLEUS; FOREBRAIN; GLOBUS PALLIDUS; MALE; MESENCEPHALON; MOTOR ACTIVITY; NERVE CELL; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PRIORITY JOURNAL; RAT; SPECTROSCOPY; SPIKE WAVE; SUBSTANTIA NIGRA;

EID: 0036314884     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00844.2001     Document Type: Article

References (63)

1. Multisecond oscillations in the subthalamic nucleus: Effects of apomorphine and dopamine cell lesion
2. Altered spontaneous discharge patterns of neurons of basal ganglia output nuclei in a genetic animal model of paroxysmal dystonia
3. Physiology of MPTP tremor
4. The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism
5. Dopamine agonists increase pallidal unit activity: Attenuation by agonist pretreatment and anesthesia
6. Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurons in the MPTP-treated monkey
7. Effects of L-DOPA on neuronal activity of the globus pallidus externalis (GPe) and globus pallidus internalis (GPi) in the MPTP-treated monkey
8. Tremor at rest episodes in unilaterally 6-OHDA-induced substantia nigra lesioned rats: EEG-EMG and behavior
9. Reduction of apomorphine-induced rotational behaviour by subthalamic lesion in 6-OHDA lesioned rats is associated with a normalization of firing rate and discharge pattern of pars reticulata neurons
10. Effects on precise motor responding of bilateral 6-hydroxydopamine infusion into the substantia nigra
11. Nigrostriatal lesion alters neurophysiological responses to selective and non-selective D-1 and D-2 dopamine agonists in rat globus pallidus
12. Motor functions of the basal ganglia as revealed by studies of single cell activity in the behaving primate
13. Effects of interruption of the nigrostriatal pathway and of dopaminergic agents on the spontaneous activity of globus pallidus neurons in the awake monkey
14. Abnormal spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism
15. Effects of dopamine agonists on the spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism
16. Tremulous characteristics of the vacuous jaw movements induced by pilocarpine and ventrolateral striatal dopamine depletions
17. Deficit of striatal parvalbumin-reactive GABAergic interneurons and decreased basal ganglia output in a genetic rodent model of idiopathic paroxysmal dystonia
18. A prescription for period analysis of unevenly sampled time series
19. Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats
20. Dynamics of tremor-related oscillations in the human globus pallidus: A single case study
21. Effects of apomorphine on globus pallidus neurons in parkinsonian patients
22. Identification and characterization of neurons with tremor-frequency activity in human globus pallidus
23. The organization of the basal ganglia-thalamocortical circuits: Open interconnected rather than closed segregated
24. Hypokinesia, rigidity, and tremor induced by hypothalamic 6-OHDA lesions in the rat
25. Burst and oscillation as disparate neuronal properties
26. 1 receptor agonists increase the firing rates of subthalamic nucleus neurons
27. Effects of apomorphine on subthalamic nucleus and globus pallidus internus neurons in patients with Parkinson's disease
28. Incomplete nigrostriatal dopaminergic cell loss and partial reductions in striatal dopamine produce akinesia, rigidity, tremor, and cognitive deficits in middle-aged rats
29. Neuronal recordings in Parkinson's disease patients with dyskinesias induced by apomorphine
30. Electrophysiological properties of nigrothalamic neurons after 6-hydroxydopamine lesions in the rat
31. Relationship of activity in the subthalamic nucleus-globus pallidus network to cortical electroencephalogram
32. Dopamine regulates the impact of the cerebral cortex on the subthalamic nucleus-globus pallidus network
33. Physiological and pathological tremors and rhythmic central motor control
34. Apomorphine induces changes in GPi spontaneous outflow in patients with Parkinson's disease
35. Altered tonic activity of neurons in the globus pallidus and subthalamic nucleus in the primate MPTP model of parkinsonism
36. The basal ganglia: Focused selection and inhibition of competing motor programs
37. Substantia nigra pars reticulata single unit activity in normal and 6OHDA-lesioned rats: Effects of intrastriatal apomorphine and subthalamic lesions
38. Neurons in the globus pallidus do not show correlated activity in the normal monkey, but phase-locked oscillations appear in the MPTP model of parkinsonism
39. Pathophysiology of the basal ganglia in Parkinson's disease
40. The role of deep brain stimulation as a surgical treatment for Parkinson's disease
41. Forelimb akinesia in the rat Parkinson model: Differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test
42. Internal globus pallidus discharge is nearly suppressed during levodopa-induced dyskinesias
43. Firing patterns and correlations of spontaneous discharge of pallidal neurons in the normal and the tremulous 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine vervet model of Parkinsonism
44. The basal ganglia: A vertebrate solution to the selection problem?
45. Acute monoaminergic depletion in the rat potentiates the excitatory effect of the subthalamic nucleus in the substantia nigra pars reticulata but not the pallidal complex
46. Hemispheric asymmetries in spontaneous firing characteristics of substantia nigra pars reticulata neurons following a unilateral 6-hydroxydopamine lesion of the rat nigrostriatal pathway
47. Multisecond oscillations in firing rate in the basal ganglia: Robust modulation by dopamine receptor activation and anesthesia
48. Dopamine agonist-mediated rotation in rats with unilateral nigrostriatal lesions is not dependent on net inhibitions of rate in basal ganglia output nuclei
49. Drugs used in the treatment of attention deficit/hyperactivity disorder affect postsynaptic firing rate and oscillation without preferential dopamine autoreceptor action
50. Firing rates and multisecond oscillations in the rodent entopeduncular nucleus (EPN): Effects of dopamine (DA) agonists and nigrostriatal lesion
51. Subthalamic nucleus lesion regularizes firing patterns in globus pallidus and substantia nigra pars reticulata in rats
52. Studies in astronomical time series analysis. II. Statistical aspects of spectral analysis of unevenly spaced data
53. Posture-independent sensorimotor analysis of inter-hemispheric receptor asymmetries in neostriatum
54. Behavioral stimulation induced by muscimol and other GABA agonists injected into the substantia nigra
55. Effects of increasing doses of apomorphine during stereotaxic neurosurgery in Parkinson's disease: Clinical score and internal globus pallidus activity
56. Subthalamic nucleus lesions reduce low frequency oscillatory firing of substantia nigra pars reticulata neurons in a rat model of Parkinson's disease
57. Physiology of hypokinetic and hyperkinetic movement disorders: Model for dyskinesia
58. Effects of dopamine receptor stimulation on basal ganglia activity
59. Effect of dopamine system activation on substantia nigra pars reticulata output neurons: Variable single-unit responses in normal rats and inhibition in 6-hydroxydopamine-lesioned rats
60. D-1 dopamine receptor stimulation potentiates neurophysiological effects of bromocriptine in rats with lesions of the nigrostriatal dopamine pathway
61. 2 coactivation induces potentiated responses
62. Comparison of MPTP-induced changes in spontaneous neuronal discharge in the internal pallidal segment and in the substantia nigra pars reticulata in primates