Effects of apomorphine on globus pallidus neurons in parkinsonian patients

Annals of Neurology

Volumn 42, Issue 5, 1997, Pages 767-775

  Hutchison, W D ^a   Levy, R ^b   Dostrovsky, J O ^a,b   Lozano, A M ^a   Lang, A E ^a  

^a TORONTO WESTERN HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOMORPHINE; BRITAJECT; LEVODOPA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; GLOBUS PALLIDUS; HUMAN; NERVE CELL MEMBRANE POTENTIAL; NEUROSURGERY; PARKINSON DISEASE; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

ACTION POTENTIALS; AGED; ANTIPARKINSON AGENTS; APOMORPHINE; ELECTROPHYSIOLOGY; GLOBUS PALLIDUS; HUMANS; MIDDLE AGED; NEURONS; PARKINSON DISEASE; TIME FACTORS;

EID: 0030853296     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.410420513     Document Type: Article

References (36)

1. Albin RL, Young AB, Penney JB. The functional anatomy of basal ganglia disorders. Trends Neurosci 1989;12:366-375
2. DeLong MR. Primate models of movement disorders of basal ganglia origin. Trends Neurosci 1990;13:281-285
3. Albin RL. The pathophysiology of chorea/ballism and parkinsonism. Parkinsonism Rel Disord 1995;1:3-11
4. Wichmann T, DeLong MR. Functional and pathophysiological models of the basal ganglia. Curr Opin Neurobiol 1996;6:751-758
5. Parent A, Hazrati L-N. Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop. Brain Res Rev 1995;20:91-127
6. Carpenter MB. Corpus striatum and related nuclei. In: Satterfield TS, ed. Core text of neuroanatomy. 4th ed. Baltimore: Williams and Wilkins, 1991:325-360
7. Miller WC, DeLong MR. Parkinsonian symptomatology. An anatomical and physiological analysis. Ann NY Acad Sci 1989; 515:287-302
8. Filion M, Tremblay L. Abnormal spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism. Brain Res 1991;547:142-151
9. Filion M, Tremblay L, Bédard PJ. Effects of dopamine agonists on the spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism. Brain Res 1991;547: 152-161
10. Hutchison WD, Lozano CA, Davis KD, et al. Differential neuronal activity in segments of globus pallidus in Parkinson's disease patients. Neuroreport 1994;5:1533-1537
11. Vitek J, Kaneoke Y, Turner R, et al. Neuronal activity in the internal (GPi) and external (GPe) segments of the globus pallidus (GP) of parkinsonian patients is similar to that in the MPTP-treated primate model of parkinsonism. Soc Neurosci Abstr 1993;19:1584 (Abstract)
12. Lang AE. Hemiatrophy, juvenille-onset exertional alternating leg paresis, hypotonia, and hemidystonia and adult-onset hemiparkinsonism: the spectrum of hemiparkinsonism-hemiatrophy syndrome. Mov Disord 1995;3:1-7
13. Lang AE, Fahn S. Assessment of Parkinson's disease. In: Munsat LT, ed. Quantification of neurologic deficit. Boston: Butterworths, 1989:285-301
14. Lozano AM, Hutchison WD, Kiss ZHT, et al. Methods for microelectrode-guided posteroventral pallidotomy. J Neurosurg 1996;84:194-202
15. Schaltenbrand G, Wahren W. Atlas for stereotaxy of the human brain. Stuttgart: Georg Thieme, 1977
16. Laitinen LV, Bergenheim AT, Hariz MI. Ventroposterolateral pallidotomy can abolish all parkinsonian symptoms. Stereotact Funct Neurosurg 1992;58:14-21
17. DeLong MR. Activity of pallidal neurons during movement. J Neurophysiol 1971;34:414-427
18. Wichmann T, DeLong MR. Pathophysiology of parkinsonian motor abnormalities. Adv Neurol 1993;60:53-61
19. Gerfen CR. Dopamine receptor function in the basal ganglia. Clin Neuropharmacol 1995;18:s162-s177
20. Gancher S. Pharmacokinetics of apomorphine in Parkinson's disease. J Neural Transm 1995;45(suppl):137-141
21. Gancher S, Nutt J, Woodward WR. Apomorphine infusional therapy in Parkinson's disease: clinical utility and lack of tolerance. Mov Disord 1995;10:37-43
22. Nutt J, Gancher S, Woodward WR. Does an inhibitory action of levodopa contribute to motor fluctuations? Neurology 1988; 38:1553-1557
23. Carlson JH, Bergstrom DA, Demo SD, Walters JR. Nigrostriatal lesion alters neurophysiological responses to selective and nonselective D1 and D2 dopamine agonists in globus pallidus. Synapse 1990;5:83-93
24. Weick BG, Walters JR. Effects of D1 and D2 dopamine receptor stimulation on the activity of substantia nigra pars reticulata neurons in 6-hydroxydopamine lesioned rats: D1/D2 coactivation induces potentiated responses. Brain Res 1987;405:234-246
25. Walters JR, Kelland MD, Huang K-X, Bergstrom DA. Effects of dopamine agonists on neuronal activity in the basal ganglia of normal and dopamine-denervated rats. In: Hefti F, Weiner WJ, eds. Progress in Parkinson's disease research-2. Mount Kisco, NY: Futura Publishing, 1992:229-257
26. Filion M. Effects of interruption of the nigrostriatal pathway and of dopaminergic agents on the spontaneous activity of globus pallidus neurons in the awake monkey. Brain Res 1979; 178:425-441
27. Cheramy A, Leviel V, Glowinski J. Dendritic release of dopamine in the substantia nigra. Nature 1981;289:537-542
28. Bergstrom DA, Bromley SD, Walters JR. Apomorphine increases the activity of rat globus pallidus neurons. Brain Res 1982;238:266-271
29. Blanchet PJ, Bédard PJ, Britton DR, et al. Differential effect of selective D1 and D2 dopamine receptor agonists on levodopa-induced dyskinesia in MPTP-exposed monkeys. J Pharmacol Exp Ther 1993;267:275-279
30. Bédard PJ, Gomez-Mancilla B, Blanchette P, et al. Role of selective D1 and D2 agonists in inducing dyskinesia in drug-naive MPTP monkeys. Adv Neurol 1993;60:113-118
31. Tremblay L, Filion M. Responses of pallidal neurons to striatal stimulation in intact waking monkeys. Brain Res 1989;498: 1-16
32. Filion M, Tremblay L, Matsumura M, Richard H. Focalisation dynamique de la convergence informationelle dans les noyaux gris centraux. Rev Neurol 1994;150:627-633
33. Crossman AR. A hypothesis on the pathophysiological mechanisms that underlie levodopa-or dopamine-agonist-induced dyskinesia in Parkinson's disease: implications for future strategies in treatment. Mov Disord 1990;5:100-108
34. Lozano AM, Lang AE, Gálvez-Jiménez N, et al. GPi pallidotomy improves motor function in patients with Parkinson's disease. Lancet 1995;346:1383-1387
35. Marsden CD, Obeso JA. The functions of the basal ganglia and the paradox of stereotaxic surgery in Parkinson's disease. Brain 1994;117:877-897
36. Page RD, Sambrook MA, Crossman AR. Thalamotomy for the alleviation of levodopa-induced dyskinesia: experimental studies in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated parkinsonian monkey. Neuroscience 1993;55:147-165