Early nerve regeneration after Achilles tendon rupture - A prerequisite for healing? A study in the rat

Journal of Orthopaedic Research

Volumn 20, Issue 4, 2002, Pages 849-856

  Ackermann, Paul W ^a   Ahmed, Mahmood ^a   Kreicbergs, Andris ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Achilles tendon; Calcitonin gene related peptide; GAP 43; Immunohistochemistry; Neuropeptide Y; Peripheral nerves; Rupture

Indexed keywords

BLOOD VESSELS; FIBERS; GENES; NEUROLOGY; PROTEINS; TENDONS; TISSUE;

ANGEOGENESIS; IMMUNOREACTIVITY; NERVE REGENERATION;

ORTHOPEDICS;

BIOLOGICAL MARKER; CALCITONIN GENE RELATED PEPTIDE; GENE PRODUCT; NEUROMODULIN; NEUROPEPTIDE Y;

ACHILLES TENDON RUPTURE; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVE; BLOOD VESSEL; CELL PROLIFERATION; CONNECTIVE TISSUE; CONTROLLED STUDY; ENDOTHELIUM CELL; FIBROBLAST; HEALING; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NERVE ENDING; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT; SENSORY NERVE; TIME; VASOCONSTRICTION; VASODILATATION;

ACHILLES TENDON; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; GAP-43 PROTEIN; IMMUNOHISTOCHEMISTRY; MALE; NERVE REGENERATION; NEUROPEPTIDE Y; RATS; RATS, SPRAGUE-DAWLEY; RUPTURE; THIOLESTER HYDROLASES; UBIQUITIN THIOLESTERASE; WOUND HEALING;

EID: 0036312177     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-0266(01)00159-0     Document Type: Article

References (39)

1. Sensory neuropeptidergic pattern in tendon, ligament and joint capsule. A study in the rat
2. Autonomic innervation of tendons, ligaments and joint capsules. A morphologic and quantitative study in the rat
3. Bone morphogenetic proteins and tendon repair
4. Nerve regeneration during patellar tendon autograft remodelling after anterior cruciate ligament reconstruction: An experimental and clinical study
5. GAP-43 mRNA and calcitonin gene-related peptide mRNA expression in sensory neurons are increased following sympathectomy
6. Sensory neuropeptides: Their role in inflammation and wound healing
7. Calcitonin gene-related peptide is a potent vasodilator
8. Neuropeptide control of bone marrow neutrophil production. A key axis for neuroimmunomodulation
9. GAP-43 expression in primary sensory neurons following central axotomy
10. Shared and unique roles of CAP-23 and GAP-43 in actin regulation, neurite outgrowth, and anatomical plasticity
11. Absence of GAP-43 can protect neurons from death
12. Potentiation of tachykinin-induced plasma protein extravasation by calcitonin gene-related peptide
13. Cellular shape and pressure may mediate mechanical control of tissue composition in tendons
14. Revascularization of ischemic tissues with SIKVAV and neuropeptide Y (NPY)
15. Immunoreactive neuropeptides in nerves in ligamentous tissue. An experimental neuroimmunohistochemical study
16. Calcitonin gene-related peptide stimulates proliferation of human endothelial cells
17. Effect of sciatic nerve section on neural ingrowth into the rat tibial fracture callus
18. Rapid proliferation of calcitonin gene-related peptide-immunoreactive nerves during healing of rat tibial fracture suggests neural involvement in bone growth and remodelling
19. Neuropeptides - An overview
20. Reinnervation and neuropeptides in mouse skin flaps
21. Sensory peptides as neuromodulators of wound healing in aged rats
22. Distribution of GAP-43 in relation to CGRP and synaptic vesicle markers in rat skeletal muscles during development
23. GAP-43 and its relation to autonomic and sensory neurons in sciatic nerve and gastrocnemius muscle in the rat
24. Substance P and calcitonin gene-related peptide expression at the extensor carpi radialis brevis muscle origin: Implications for the etiology of tennis elbow
25. Sympathetic and sensory innervations are heterogeneously distributed in relation to the blood vessels at the extensor carpi radialis brevis muscle origin of man
26. Morphological and immunohistochemical examination of nerves in normal and injured collateral ligaments of rat, rabbit, and human knee joints
27. A role for calcitonin gene-related peptide in rabbit knee joint ligament healing
28. Procalcitonin and calcitonin gene-related peptide decrease LPS-induced tnf production by human circulating blood cells
29. B-50, the growth associated protein-43: Modulation of cell morphology and communication in the nervous system
30. Levels of vasodilators (SP, CGRP) and vasoconstrictor (NPY) peptides in early human burns
31. Neuropeptides: Mediators of inflammation and tissue repair?
32. Neurotransmitters as neurotrophic factors: A new set of functions
33. Fibroblast response to hypoxia: The relationship between angiogenesis and matrix regulation
34. Neuropeptide hormones as neurotrophic factors
35. Peripheral nerve injury and regeneration
36. Expression of growth-associated protein B-50 (GAP-43) in dorsal root ganglia and sciatic nerve during regenerative sprouting
37. Mechanical properties of tendons and ligaments. II. The relationships of immobilization and exercise on tissue remodeling
38. Migration of 3T3 and lung fibroblasts in response to calcitonin gene-related peptide and bombesin
39. Neuropeptide Y: A novel angiogenic factor from the sympathetic nerves and endothelium