The role of leukotriene inhibitors in allergic rhinitis and paranasal sinusitis

Expert Opinion on Pharmacotherapy

Volumn 3, Issue 1, 2002, Pages 33-38

  Parnes, Steven M ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

5 lipoxygenase; Allergic rhinitis; Asthma; Leukotrienes; Nasal polyposis; Sinusitis

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; CARBON; LEUKOTRIENE; LEUKOTRIENE A4; LEUKOTRIENE B4; LEUKOTRIENE C4; LEUKOTRIENE D4; LEUKOTRIENE D4 RECEPTOR; LEUKOTRIENE E4; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MONOLUKAST; PLACEBO; PRANLUKAST; STEROID; UNCLASSIFIED DRUG; ZAFIRLUKAST; ZILEUTON;

ALLERGIC RHINITIS; ANAPHYLAXIS; ASTHMA; BASOPHIL; CELL TYPE; CHEMICAL STRUCTURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG MECHANISM; EOSINOPHIL; HUMAN; IMMUNOLOGY; INFLAMMATION; LEUKOCYTE; LIPID METABOLISM; MACROPHAGE; MAST CELL; MONOCYTE; NOSE POLYP; PARANASAL SINUS; PARANASAL SINUSITIS; PATHOGENESIS; REVIEW; SIDE EFFECT;

CLINICAL TRIALS; HUMANS; LEUKOTRIENE ANTAGONISTS; LEUKOTRIENES; PARANASAL SINUS DISEASES; RHINITIS, ALLERGIC, PERENNIAL; TREATMENT OUTCOME;

EID: 0036310433     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.3.1.33     Document Type: Review

References (29)

1. Treatment of asthma with drugs modifying the leukotriene pathway
2. Leukotriene pathway inhibitors in asthma and chronic obstructive pulmonary disease
3. Leukotrienes in the pathogenesis of asthma
4. Release of leukotrienes, prostaglandins, and histamine into nasal secretions of aspirin-sensitive asthmatics during reaction to aspirin
5. Antileukotrienes in the treatment of asthma
6. The role of antileukotrienes in asthma management
7. Clinical pharmacology of leukotriene receptor antagonists and 5-lipoxygenase inhibitors
8. Worldwide clinical experience with the first marketed leukotriene receptor antagonist
9. Oral montelukast, inhaled beclomethasone and placebo for chronic asthma
10. Anti-leukotriene agents: A new direction in asthma therapy
11. Anti-leukotriene therapy in asthma
12. Therapeutic advances: Leukotriene antagonists for the treatment of asthma
13. Montelukast for chronic asthma in 6-and 14-year old children: A randomized, double-blind trial
14. The role of leukotrienes in allergic rhinitis: A review
15. The effect of a leukotriene antagonist on the early response to antigen
16. Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor
17. 4-receptor antagonist, ICI 204,219, relieves symptoms of acute seasonal allergic rhinitis
18. Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics
19. Immunopathology of nasal polyps: An immunohistochemical approach
20. Prostaglandins, leukotrienes, and other arachidonic acid metabolites in nasal polyps and nasal mucosa
21. Cyclooxygenase and lipoxygenase metabolite generation in nasal polyps
22. Arachidonic acid metabolites and sinonasal polyposis. i. possible prognostic value
23. Eicosanoids from biopsy of normal and polypous nasal mucosa
24. Cyclooxygenase-2 mRNA is downexpressed in nasal polyps from aspirin-sensitive asthmatics
25. Antileukotriene therapy for the relief of sinus symptoms in aspirin triad disease
26. Acute effects of antileukotrienes on sinusitis and sinonasal polyposis
27. Inhibition of mediator and cytokine release from dispersed nasal polyp cells by terfenadine
28. Aspirin intolerance in patients with chronic sinusitis
29. Antileukotriene therapy for the relief of sinus symptoms in aspirin triad disease