The multimodular organization of the CNN proteins;Les protéines CCN: Quand multimodulaire rime avec multifonctionnel

Medecine/Sciences

Volumn 18, Issue 6-7, 2002, Pages 745-756

  Perbal, Bernard ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; PROTEIN CCN; UNCLASSIFIED DRUG;

CARCINOGENESIS; CELL ADHESION; CELL GROWTH; CELL MOTILITY; CELL PROLIFERATION; MULTIGENE FAMILY; PROTEIN FAMILY; REVIEW;

EID: 0036310417     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/20021867745     Document Type: Review

References (56)

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3. Identification of a phorbol ester-repressible v-src inducible gene
4. Complexity of the early genetic response to growth factors in mouse fibroblasts
5. Structure, mapping, and expression of fisp-12, a growth factor - Inducible gene encoding a secreted cysteine-rich protein
6. Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
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9. WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors
10. Identification of rCop-1, a new member of the CCN protein family, as a negative regulator for cell transformation
11. Expression of the ELM1 gene, a novel gene of the CCN (connective tissue growth factor, Cyr61/Cef10, and nephroblastoma overexpressed gene) family, suppresses in vivo tumor growth and metastasis of K-1735 murine melanoma cells
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31. Cloning of a mRNA preferentially expressed in chondrocytes by differential display-PCR from a human chondrocytic cell line that is identical with connective tissue growth factor (CTGF) mRNA
32. Cyr61, Product of a growth factor-inducible immediate-early gene, regulates chondrogenesis in mouse limb bud mesenchymal cells
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34. The expression of chicken nov, a member of the CCN gene family in early stage development. Gene expression pattern
35. In vitro evidence for differential involvement of CTGF, TGFbeta, and PDGF-BB in mesangial response to injury
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41. Transcriptional down regulation of the nov proto-oncogene in fibroblasts transformed by p60v-src
42. Nephroblastoma overexpressed gene (NOV) codes for a growth factor that induces protein tyrosine phosphorylation
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44. CyR61 Stimulates human skin fibroblast migration through integrin alpha vbeta 5 and enhances mitogenesis through integrin alpha vbeta 3, independent of its corboxyl-terminal domain
45. Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycans
46. The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts
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56. A novel variant of WISP1 lacking a van Willebrand type C module overexpressed in scirrhous gastric carcinoma