-
1
-
-
0027175882
-
Phase II trial of orally administered Miltefosine in advanced colorectal cancer
-
Becher R, Kloke O, Füger A, Bremer K, Drozd A, Kleeberg UR, Fritze D, Rieche K, Sindermann H (1993) Phase II trial of orally administered Miltefosine in advanced colorectal cancer. Onkologie 16: 11
-
(1993)
Onkologie
, vol.16
, pp. 11
-
-
Becher, R.1
Kloke, O.2
Füger, A.3
Bremer, K.4
Drozd, A.5
Kleeberg, U.R.6
Fritze, D.7
Rieche, K.8
Sindermann, H.9
-
2
-
-
0001990739
-
Erucyphosphocholine is a second generation alkylphosphocholine (APC)
-
83rd Annual meeting of the American Association of Cancer Research. San Diego, 20-23 May 1992
-
Berger MR, Eibl H (1992) Erucyphosphocholine is a second generation alkylphosphocholine (APC). 83rd Annual meeting of the American Association of Cancer Research. San Diego, 20-23 May 1992. Proc Am Assoc Cancer Res 33: 416
-
(1992)
Proc Am Assoc Cancer Res
, vol.33
, pp. 416
-
-
Berger, M.R.1
Eibl, H.2
-
4
-
-
0028924499
-
Analogs of alkyllysophospholipids: Chemistry, effects on the molecular level and their consequences for normal and malignant cells
-
Brachwitz H, Vollgraf C (1995) Analogs of alkyllysophospholipids: chemistry, effects on the molecular level and their consequences for normal and malignant cells. Pharmacol Ther 66: 39
-
(1995)
Pharmacol Ther
, vol.66
, pp. 39
-
-
Brachwitz, H.1
Vollgraf, C.2
-
5
-
-
0027455786
-
Induction of apoptosis in human leukemic cells by the ether lipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine. A possible basis for its selective action
-
Diomede L, Colotta F, Piovani B, Re F, Modest EJ, Salmona M (1993) Induction of apoptosis in human leukemic cells by the ether lipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine. A possible basis for its selective action. Int J Cancer 53: 124
-
(1993)
Int J Cancer
, vol.53
, pp. 124
-
-
Diomede, L.1
Colotta, F.2
Piovani, B.3
Re, F.4
Modest, E.J.5
Salmona, M.6
-
6
-
-
0028216601
-
The induction of apoptosis is a common feature of ether-linked glycerophospholipids in human leukemic cells
-
Diomede L, Piovani B, Re F, Principe P, Colotta F, Modest EJ (1994) The induction of apoptosis is a common feature of ether-linked glycerophospholipids in human leukemic cells. Int J Cancer 57: 645
-
(1994)
Int J Cancer
, vol.57
, pp. 645
-
-
Diomede, L.1
Piovani, B.2
Re, F.3
Principe, P.4
Colotta, F.5
Modest, E.J.6
-
7
-
-
0029052647
-
Induction of a retinoblastoma phosphatase activity by anticancer drugs accompanies p53-independent G1 arrest and apoptosis
-
Dou QP, An B, Will PL (1995) Induction of a retinoblastoma phosphatase activity by anticancer drugs accompanies p53-independent G1 arrest and apoptosis. Proc Natl Acad Sci USA 92: 9019
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9019
-
-
Dou, Q.P.1
An, B.2
Will, P.L.3
-
8
-
-
0026733847
-
Synthesis of hexadecylphosphocholine (Miltefosine)
-
Eibl H, Hilgard P, Unger C (eds) Karger, Basel
-
Eibl H, Engel J (1992) Synthesis of hexadecylphosphocholine (Miltefosine). In: Eibl H, Hilgard P, Unger C (eds) Progress in experimental tumor research, vol 34. New drugs in cancer therapy. Karger, Basel, pp 1-5
-
(1992)
Progress in Experimental Tumor Research, Vol 34. New Drugs in Cancer Therapy
, vol.34
, pp. 1-5
-
-
Eibl, H.1
Engel, J.2
-
10
-
-
0029115973
-
Taxol cytotoxicity on human leukemia cell lines is a function of their susceptibility to programmed cell death
-
Gangemi RM, Tiso M, Marchetti C, Severi AB, Fabbi M (1995) Taxol cytotoxicity on human leukemia cell lines is a function of their susceptibility to programmed cell death. Cancer Chemother Pharmacol 36: 385
-
(1995)
Cancer Chemother Pharmacol
, vol.36
, pp. 385
-
-
Gangemi, R.M.1
Tiso, M.2
Marchetti, C.3
Severi, A.B.4
Fabbi, M.5
-
11
-
-
0026315413
-
The phospholipid analogue, hexadecylphosphocholine, inhibits protein kinase C in vitro and antagonises phorbol ester-stimulated cell proliferation
-
Geilen CC, Haase R, Buchner K, Wieder T, Hucho F, Reutter W (1991) The phospholipid analogue, hexadecylphosphocholine, inhibits protein kinase C in vitro and antagonises phorbol ester-stimulated cell proliferation. Eur J Cancer 27: 1650
-
(1991)
Eur J Cancer
, vol.27
, pp. 1650
-
-
Geilen, C.C.1
Haase, R.2
Buchner, K.3
Wieder, T.4
Hucho, F.5
Reutter, W.6
-
12
-
-
0026726606
-
Hexadecylphosphocholine inhibits translocation of CTP: Choline-phosphate cytidyltransferase in Madin-Darby canine kidney cells
-
Geilen CC, Wieder T, Reutter W (1991) Hexadecylphosphocholine inhibits translocation of CTP: choline-phosphate cytidyltransferase in Madin-Darby canine kidney cells. J Biol Chem 267: 6719
-
(1991)
J Biol Chem
, vol.267
, pp. 6719
-
-
Geilen, C.C.1
Wieder, T.2
Reutter, W.3
-
13
-
-
0028323520
-
Phospholipid analogues: Side chain- and polar head-dependent effects on phosphatidylcholine biosynthesis
-
Geilen CC, Haase A, Wieder T, Arndt D, Zeisig R, Reutter W (1994) Phospholipid analogues: side chain- and polar head-dependent effects on phosphatidylcholine biosynthesis. J Lipid Res 35: 625
-
(1994)
J Lipid Res
, vol.35
, pp. 625
-
-
Geilen, C.C.1
Haase, A.2
Wieder, T.3
Arndt, D.4
Zeisig, R.5
Reutter, W.6
-
14
-
-
0028967202
-
Effects of hexadecylphosphocholine on fatty acid metabolism: Relation to cytotoxicity
-
Goppelt-Struebe M, Winter I (1995) Effects of hexadecylphosphocholine on fatty acid metabolism: relation to cytotoxicity. Cancer Chemother Pharmacol 35: 519
-
(1995)
Cancer Chemother Pharmacol
, vol.35
, pp. 519
-
-
Goppelt-Struebe, M.1
Winter, I.2
-
15
-
-
0023772929
-
Characterisation of antitumor activity of hexadecylphosphocholine (D 18506)
-
Hilgard P, Stekar J, Voegeli R, Engel J, Schumacher W, Eibl H, Unger C, Berger MR (1988) Characterisation of antitumor activity of hexadecylphosphocholine (D 18506). Eur J Cancer Clin Oncol 24: 1457
-
(1988)
Eur J Cancer Clin Oncol
, vol.24
, pp. 1457
-
-
Hilgard, P.1
Stekar, J.2
Voegeli, R.3
Engel, J.4
Schumacher, W.5
Eibl, H.6
Unger, C.7
Berger, M.R.8
-
17
-
-
0028316195
-
Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C
-
Jarvis WD, Turner AJ, Povirk LF, Traylor RS, Grant S (1994) Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C. Cancer Res 54: 1707
-
(1994)
Cancer Res
, vol.54
, pp. 1707
-
-
Jarvis, W.D.1
Turner, A.J.2
Povirk, L.F.3
Traylor, R.S.4
Grant, S.5
-
18
-
-
0027931454
-
Pharmacokinetic behavior and antineoplastic activity of liposomal hexadecylphosphocholine
-
Kaufmann-Kolle P, Drevs J, Berger MR, Kötting J, Marschner N, Unger C Eibl H (1994) Pharmacokinetic behavior and antineoplastic activity of liposomal hexadecylphosphocholine. Cancer Chemother Pharmacol 34: 393
-
(1994)
Cancer Chemother Pharmacol
, vol.34
, pp. 393
-
-
Kaufmann-Kolle, P.1
Drevs, J.2
Berger, M.R.3
Kötting, J.4
Marschner, N.5
Unger, C.6
Eibl, H.7
-
19
-
-
0026506456
-
Alkylphosphocholines: Influence of structural variation on biodistribution at antineoplastically active concentrations
-
Kötting J, Berger MR, Unger C, Eibl H (1992) Alkylphosphocholines: influence of structural variation on biodistribution at antineoplastically active concentrations. Cancer Chemother Pharmacol 30: 105
-
(1992)
Cancer Chemother Pharmacol
, vol.30
, pp. 105
-
-
Kötting, J.1
Berger, M.R.2
Unger, C.3
Eibl, H.4
-
20
-
-
0025185463
-
Induction of apoptosis (programmed cell death) in human leukemic cells, by inhibitors of RNA protein synthesis
-
Martin S, Lennon S, Bonham A, Cotter TG (1990) Induction of apoptosis (programmed cell death) in human leukemic cells, by inhibitors of RNA protein synthesis. J Immunol 145: 1859
-
(1990)
J Immunol
, vol.145
, pp. 1859
-
-
Martin, S.1
Lennon, S.2
Bonham, A.3
Cotter, T.G.4
-
21
-
-
0026690153
-
Induction of tumor cell differentiation by alkylphosphocholines: A new approach for in vitro screening
-
Maurer HR, Hilgard P (1992) Induction of tumor cell differentiation by alkylphosphocholines: a new approach for in vitro screening. Prog Exp Tumor Res 34: 90
-
(1992)
Prog Exp Tumor Res
, vol.34
, pp. 90
-
-
Maurer, H.R.1
Hilgard, P.2
-
22
-
-
0027979832
-
BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death
-
McGahon A, et al (1994) BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death. Blood 83: 1179
-
(1994)
Blood
, vol.83
, pp. 1179
-
-
McGahon, A.1
-
23
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55
-
(1983)
J Immunol Methods
, vol.65
, pp. 55
-
-
Mosmann, T.1
-
24
-
-
0027459908
-
Phase II study of daily oral Miltefosine (hexadecylphosphocholine) in advanced coloreclal cancer
-
Planting AST, Stoter G, Verwij J (1993) Phase II study of daily oral Miltefosine (hexadecylphosphocholine) in advanced coloreclal cancer. Eur J Cancer 29A: 518
-
(1993)
Eur J Cancer
, vol.29 A
, pp. 518
-
-
Planting, A.S.T.1
Stoter, G.2
Verwij, J.3
-
25
-
-
0027468561
-
Structure-activity relationships of four anti-cancer alkylphosphocholine derivatives in vitro and in vivo
-
Sobotka SB, Berger MR, Eibl H (1993) Structure-activity relationships of four anti-cancer alkylphosphocholine derivatives in vitro and in vivo. Int J Cancer 53: 418
-
(1993)
Int J Cancer
, vol.53
, pp. 418
-
-
Sobotka, S.B.1
Berger, M.R.2
Eibl, H.3
-
26
-
-
0028341492
-
Cathepsin B activity in human lung tumor cell lines: Ultrastructural localization, pH sensitivity, and inhibitor status at the cellular level
-
Spiess E, Brüning A, Gack S, Ulbricht B, Spring H, Günter T, Ebert W (1994) Cathepsin B activity in human lung tumor cell lines: ultrastructural localization, pH sensitivity, and inhibitor status at the cellular level. J Histochem Cytochem 42: 917
-
(1994)
J Histochem Cytochem
, vol.42
, pp. 917
-
-
Spiess, E.1
Brüning, A.2
Gack, S.3
Ulbricht, B.4
Spring, H.5
Günter, T.6
Ebert, W.7
-
27
-
-
0027320780
-
Antineoplastic activity and tolerability of a novel heterocyclic alkylphospholipid. D-20133
-
Stekar J, Hilgard P, Voegeli R, Maurer HR, Engel J, Kutscher B, Nößner G, Schumacher W (1993) Antineoplastic activity and tolerability of a novel heterocyclic alkylphospholipid. D-20133. Cancer Chemother Pharmacol 32: 437
-
(1993)
Cancer Chemother Pharmacol
, vol.32
, pp. 437
-
-
Stekar, J.1
Hilgard, P.2
Voegeli, R.3
Maurer, H.R.4
Engel, J.5
Kutscher, B.6
Nößner, G.7
Schumacher, W.8
-
28
-
-
0026621940
-
Hexadecylphosphocholine in the topical treatment of skin metastases in breast cancer
-
Unger C, Sindermann H, Peukert M, Hilgard P, Engel J, Eibl H (1992) Hexadecylphosphocholine in the topical treatment of skin metastases in breast cancer. Prog Exp Tumor Res 34: 153
-
(1992)
Prog Exp Tumor Res
, vol.34
, pp. 153
-
-
Unger, C.1
Sindermann, H.2
Peukert, M.3
Hilgard, P.4
Engel, J.5
Eibl, H.6
-
29
-
-
0027430881
-
Daily oral Miltefosine (hexadecylphosphocholine) in patients with advanced breast cancer: A phase II study
-
Unger C, Becher R, Rieche K, Wandler HE, Friedlich G, Edler L (1993) Daily oral Miltefosine (hexadecylphosphocholine) in patients with advanced breast cancer: a phase II study. Onkologie 16: 260
-
(1993)
Onkologie
, vol.16
, pp. 260
-
-
Unger, C.1
Becher, R.2
Rieche, K.3
Wandler, H.E.4
Friedlich, G.5
Edler, L.6
-
30
-
-
0026531516
-
Hexadecylphosphocholine stimulates the colony-stimulating factor-dependent growth of haematopoietic progenitor cells
-
Vehmayer K, Eibl H, Unger C (1992) Hexadecylphosphocholine stimulates the colony-stimulating factor-dependent growth of haematopoietic progenitor cells. Exp Hematol 20: 1
-
(1992)
Exp Hematol
, vol.20
, pp. 1
-
-
Vehmayer, K.1
Eibl, H.2
Unger, C.3
-
32
-
-
0029791237
-
New promising anticancer agents in development: What comes next?
-
Verweji J (1996) New promising anticancer agents in development: what comes next? Cancer Chemother Pharmacol 38 [Suppl]: S3
-
(1996)
Cancer Chemother Pharmacol
, vol.38
, Issue.SUPPL.
-
-
Verweji, J.1
-
34
-
-
0028016179
-
Hyperphosphorylation of p53 induced by okadaic acid attenuates its transcriptional activation function
-
Zhang W, McClain C, Gau J, Quo XD, Deisseroth AB (1994) Hyperphosphorylation of p53 induced by okadaic acid attenuates its transcriptional activation function. Cancer Res 54: 4448
-
(1994)
Cancer Res
, vol.54
, pp. 4448
-
-
Zhang, W.1
McClain, C.2
Gau, J.3
Quo, X.D.4
Deisseroth, A.B.5
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