XKCM1 acts on a single protofilament and requires the C terminus of tubulin

Journal of Molecular Biology

Volumn 316, Issue 3, 2002, Pages 817-828

  Niederstrasser, Hanspeter ^a   Salehi Had, Hani ^a   Gan, Eugene C ^b   Walczak, Claire ^b   Nogales, Eva ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INDIANA UNIVERSITY   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

GDP tubulin rings; Kin I kinesins; MTs; XKCM1; Zinc macrotubes

Indexed keywords

GUANOSINE DIPHOSPHATE; KINESIN; POLYMER; PROTEIN; PROTEIN KIN I; PROTEIN XKCM1; SUBTILISIN; TUBULIN; UNCLASSIFIED DRUG; ZINC;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; DEPOLYMERIZATION; ENZYME ACTIVITY; MICROTUBULE; MITOSIS SPINDLE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REGULATORY MECHANISM;

EID: 0036303294     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5360     Document Type: Article

References (37)

1. Dynamic instability of microtubule growth
2. GDP state of tubulin: Stabilization of double rings
3. Cold depolymerization of microtubules to double rings: Geometric stabilization of assemblies
4. The free energy of hydrolysis of a microtubule-bound nucleotide triphosphate is near zero: All of the free energy for hydrolysis is stored in the microtubule lattice
5. Microtubules dynamics and microtubules caps: A time-resolved cryo-electron microscopy study
6. Real-time visualization of cell cycle-dependent changes in microtubule dynamics
7. Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts
8. XKCM1: A Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly
9. Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility
10. Kin I kinesins are microtubule-destabilizing enzymes
11. Molecular dissection of the microtubule depolymerizing activity of mitotic centromere-associated kinesin
12. Stu2 promotes mitotic spindle elongation in anaphase
13. The three-dimensional structure of tubulin protofilaments
14. Structure of the αβ tubulin dimer by electron crystallography
15. Tubulin conformation in zinc-induced sheets and macrotubes
16. Studies of crystallizaton conditions for native and subtilisin-cleaved pig brain tubulin
17. Cryo-electron microscopy of GDP-tubulin rings
18. Visualizing a new binding site of ncd-motor domain on tubulin
19. 3D electron microscopy of the interaction of kinesin with tubulin
20. Image reconstructions of microtubules decorated with monomeric and dimeric kinesins: Comparison with X-ray structure and implications for motility
21. 15 Å resolution model of the monomeric kinesin motor, KIF1A
22. The refined structure of tubulin at 3.5 Å
23. Mechanism of the single-headed processivity: Diffusional anchoring between the K-loop of kinesin and the C terminus of tubulin
24. Engineering the processive run length of the kinesin motor
25. Kinesin does not support the motility of zinc-macrotubes
26. Structure and function in the tubulin dimer and the role of the acidic carboxyl terminus
27. High resolution structure of the microtubule
28. Common and distinct tubulin binding sites for microtubule-associated proteins
29. 2 interaction
30. Assembly properties of tubulin after carboxyl group modification
31. Polymorphic assembly of subtilisin-cleaved tubulin
32. Structures of kinesin and kinesin-microtubule interactions
33. HIV-1 Rev depolymerizes microtubules to form stable bilayered rings
34. Preparation of marked microtubules for the assay of the polarity of microtubule based motors by fluorescence
35. Subtilisin cleavage of tubulin heterodimers and polymers
36. C-terminal cleavage of tubulin by subtilisin enhances ring formation
37. Switch-based mechanism of kinesin motors