Cladribine decreases the level of angiogenic factors in patients with chronic lymphocytic leukemia

Neoplasma

Volumn 49, Issue 3, 2002, Pages 145-148

  Gora Tybor, J ^a   Blonski, J Z ^a   Robak, T ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

2 chlorodeoxyadenosine; Angiogenesis; Angiogenic factors; bFGF; Chronic lymphocytic leukemia; TGF 1

Indexed keywords

ANGIOGENIC FACTOR; BASIC FIBROBLAST GROWTH FACTOR; CLADRIBINE; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER REGRESSION; CANCER STAGING; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; TREATMENT OUTCOME;

EID: 0036302990     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. National Cancer Institute - Sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
2. Increased intracellular and plasma levels of basic fibroblast growth factor in B-cell chronic lymphocytic leukemia
3. Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularisation by low-dose methotrexate
4. Synthesis of 2′-deoxynucleosides adenosin and related 2′-deoxynucleosides via a novel direct stereospecific serum salt glycosylation procedure
5. "Accidental" anti-angiogenic drugs
6. Increased bone marrow angiogenesis in B-cell chronic lymphocytic leukemia
7. Basic fibroblast growth factor (bFGF) upregulates the expression of bcl-2 in B cell chronic leukemia cell lines resulting in delaying apoptosis
8. Excessive production of transforming growth factor-β by bone marrow stromal cells in B-cell chronic lymphocytic leukemia inhibits growth of hematopoietic precursors and interleukin-6 production
9. Elevated Intracellular level of basic fibroblast growth factor correlates with stage of chronic lymphocytic leukemia and is associated with resistance to fludarabine
10. Increased serum levels of vascular endothelial growth factor predict risk of progression in early B-cell chronic lymphocytic leukaemia
11. Increased angiogenesis in the bone marrow of patients with acute leukemia
12. Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia
13. Purine analogue 6-mathylmercaptopurine riboside inhibits early and late phases of the angiogenesis process
14. Bone marrow angiogenesis in patients achieving complete response after stem cell transplantation for multiple myeloma
15. Serum levels of angiogenic cytokines in systemic lupus erythematosus and their correlation with disease activity
16. Cladribine in the treatment of chronic lymhocytic leukemia
17. Cladribine with or without prednisone in the treatment of previously treated and untreated B-cell chronic lymphocytic leukaemia - Updated results of the multicentre study of 378 patients
18. Cladribine with prednisone versus chlorambucil with prednisone as first-line therapy in chronic lymphocytic leukemia: Report of a prospective, randomized, multicenter trial
19. Clinical implications of circulating angiogenic factors in cancer patients
20. Elevated serum level of transforming growth factor beta1 in patients with colorectal carcinoma: Its association with tumor progression and its significant decrease after curative surgical resection
21. Serum transforming growth factor beta1 in patients with renal cell carcinoma
22. Elevated serum levels of transforming growth factor beta1 in Epstein-Barr virus-associated nosopharyngeal carcinoma patients