Marked inhibition of testosterone biosynthesis by the hepatotoxin nodularin due to apoptosis of Leydig cells

Molecular Carcinogenesis

Volumn 34, Issue 3, 2002, Pages 151-163

  Park, Tae Jun ^a   Song, Kye Yong ^b   Sohn, Son Hyang ^c   Lim, In Kyoung ^a  

^a Ajou University School of Medicine   (South Korea)

^b Chung Ang University   (South Korea)

^c Ajou University   (South Korea)

Author keywords

Apoptosis; Leydig cell; Nodularin; Peroxisome proliferation; Testes; Testosterone

Indexed keywords

CHOLESTEROL; NODULARIN; REGULATOR PROTEIN; STEROID 17ALPHA MONOOXYGENASE; TESTOSTERONE;

ADOLESCENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHROMATIN CONDENSATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HORMONE INHIBITION; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; LEYDIG CELL; LIVER CARCINOGENESIS; LIVER TOXICITY; LYSOSOME; MALE; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; PROSTATE; RAT; SERTOLI CELL; SPERMATOGONIUM; TESTIS; TESTOSTERONE BLOOD LEVEL; TESTOSTERONE METABOLISM; TESTOSTERONE SYNTHESIS;

ANIMALS; APOPTOSIS; BACTERIAL TOXINS; CHOLESTEROL; DIETHYLNITROSAMINE; LEYDIG CELLS; LIVER NEOPLASMS; LUTEINIZING HORMONE; MALE; PEPTIDES, CYCLIC; PROSTATE; RATS; RATS, INBRED F344; STEROID 17-ALPHA-HYDROXYLASE; TESTIS; TESTOSTERONE;

EID: 0036302170     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/mc.10059     Document Type: Article

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