Diethylnitrosamine causes pituitary damage, disturbs hormone levels, and reduces sexual dimorphism of certain liver functions in the rat

Environmental Health Perspectives

Volumn 109, Issue 9, 2001, Pages 943-947

  Liao, Dezhong Joshua ^a,d   Blanck, Agneta ^a   Eneroth, Peter ^b   Gustafsson, Jan Åke ^a   Hällström, Inger Porsch ^a,c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c SÖDERTÖRN UNIVERSITY   (Sweden)

^d KARMANOS CANCER INSTITUTE   (United States)

Author keywords

Cytochrome P450; Diethylnitrosamine; Pituitary; Sexual dimorphism

Indexed keywords

ANDROSTENEDIONE; CORTICOSTERONE; CYTOCHROME P450 2C11; CYTOCHROME P450 2C12; CYTOCHROME P450 ISOENZYME; DIETHYLNITROSAMINE; GROWTH HORMONE; LIVER ENZYME; PROLACTIN; TESTOSTERONE; UNCLASSIFIED DRUG;

ADENOHYPOPHYSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL NUCLEUS; CELL ORGANELLE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTRON MICROSCOPY; ENDOCRINE DISEASE; ENDOCRINE SYSTEM; ENDOPLASMIC RETICULUM; FEMALE; GOLGI COMPLEX; GRANULAR CELL; HORMONE BLOOD LEVEL; HYDROXYLATION; HYPERTROPHY; HYPOPHYSIS DISEASE; IN VITRO STUDY; INJECTION; LIVER FUNCTION; LIVER TOXICITY; LYSIS; MALE; MEDICAL LITERATURE; MORPHOLOGY; NONHUMAN; OBSERVATION; PARAMETER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; REDUCTION; SECRETORY CELL; SECRETORY GRANULE; SEX DIFFERENCE;

ANIMALIA;

EID: 0034781449     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.01109943     Document Type: Article

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