A critical role for the carboxy terminal region of the proprotein convertase, PACE4A, in the regulation of its autocatalytic activation coupled with secretion

Biochemical and Biophysical Research Communications

Volumn 290, Issue 2, 2002, Pages 878-884

  Taniguchi, Takazumi ^a   Kuroda, Rieko ^a   Sakurai, Kensuke ^a   Nagahama, Masami ^a   Tsuji, Akihiko ^a   Matsuda, Yoshiko ^a   Wada, Ikuo ^b  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Autoactivation; Chaperone; ER; Maturation; PACE4; Processing; Propeptide; Secretory enzyme; Sorting; The proprotein convertase

Indexed keywords

ENZYME PRECURSOR; HYBRID PROTEIN; PAIRED BASIC AMINO ACID CLEAVING ENZYME 4A; SECRETORY PROTEIN; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME RELEASE; GENE CONSTRUCT; GENE DELETION; HUMAN; HUMAN CELL; MOLECULAR SIZE; PRIORITY JOURNAL; PROTEIN FUNCTION;

MAMMALIA;

EID: 0036293595     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.6282     Document Type: Article

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