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Volumn 290, Issue 5, 2002, Pages 1602-1608

Structural investigation of the hedamycin: D(ACCGGT)2complex by NMR and restrained molecular dynamics

Author keywords

2D NMR; Drug DNA; Hedamycin; Oligonucleotide

Indexed keywords

CARBOHYDRATE DERIVATIVE; GUANINE; HEDAMYCIN; N,N DIMETHYLVANCOSAMINE SACCHARIDE; THYMINE; UNCLASSIFIED DRUG;

EID: 0036290591     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6369     Document Type: Article
Times cited : (16)

References (21)
  • 5
    • 0028944090 scopus 로고
    • Molecular basis for the DNA sequence specificity of the pluramycins. A novel mechanism involving groove interactions transmitted through the helix via intercalation to achieve sequence selectivity at the covalent bonding step
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 2430-2440
    • Sun, D.1    Hansen, M.2    Hurley, L.3
  • 7
    • 0029278899 scopus 로고
    • Hedamycin intercalates the DNA helix and, through carbohydrate-mediated recognition in the minor groove, directs N7-alkylation of guanine in the major groove in a sequence-specific manner
    • (1995) Chem. Biol. , vol.2 , pp. 229-240
    • Hansen, M.1    Yun, S.2    Hurley, L.3
  • 13
    • 0033576252 scopus 로고    scopus 로고
    • Solution structure and dynamics of a complex between DNA and the antitumor bisnaph-thalimide LU-79553: Intercalated ring flipping on the millisecond time scale
    • (1999) Biochemistry , vol.38 , pp. 15104-15115
    • Gallego, J.1    Reid, B.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.