Structural characterization of the 1:1 adduct formed between the antitumor antibiotic hedamycin and the oligonucleotide duplex d(CACGTG)2 by 2D NMR spectroscopy

Biochemistry

Volumn 35, Issue 29, 1996, Pages 9314-9324

  Pavlopoulos, Spiro ^a   Bicknell, Wendy ^a   Craik, David J ^b,c   Wickham, Geoffrey ^c  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; DOUBLE STRANDED DNA; EPOXIDE; GUANINE; HEDAMYCIN; INTERCALATING AGENT; OLIGODEOXYRIBONUCLEOTIDE;

ARTICLE; CHROMATOPHORE; DNA ADDUCT; DNA ALKYLATION; DNA DRUG COMPLEX; DNA SEQUENCE; HYDROPHOBICITY; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL;

ALKYLATION; ANTHRAQUINONES; ANTINEOPLASTIC AGENTS, ALKYLATING; BASE SEQUENCE; BINDING SITES; COMPUTER SIMULATION; DNA ADDUCTS; INTERCALATING AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES;

EID: 0029778141     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952542c     Document Type: Article

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