Behavioral and biochemical effects of new central dopamine D3 and D4 receptor antagonists in rats

Pharmacology Reviews and Communications

Volumn 12, Issue 1, 2002, Pages 39-59

  Brus, Ryszard ^a   Nowak, Przemyslaw ^a   Sokola, Andrzej ^a   Kostrzewa, Richard M ^a   Shani, Jashovan ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 5,6 DIMETHOXYINDAN; 2 DIPROPYLAMINO 7 HYDROXYTETRALIN; 3 O METHYLDOPAMINE; 3,4 DIHYDROXYPHENYLACETIC ACID; 5 HYDROXYINDOLEACETIC ACID; APOMORPHINE; BIOGENIC AMINE; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR BLOCKING AGENT; DOPAMINE 4 RECEPTOR; DOPAMINE 4 RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR BLOCKING AGENT; HALOPERIDOL; HOMOVANILLIC ACID; N (1 BENZYL 4 PIPERIDINYL) N (3 ISOPROPOXY 2 PYRIDINYL) N METHYLAMINE; NEUROLEPTIC AGENT; RECEPTOR SUBTYPE; SEROTONIN; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BIOCHEMISTRY; CATALEPSY; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE RELEASE; DOPAMINERGIC SYSTEM; DRUG EFFECT; DRUG TARGETING; EXPLORATORY BEHAVIOR; IN VIVO STUDY; LOCOMOTION; MALE; MAMMAL; MENTAL DISEASE; MICRODIALYSIS; MOLECULAR CLONING; NEUROLOGIC DISEASE; NEUROTRANSMITTER RELEASE; NONHUMAN; POTENTIOMETRY; PRIORITY JOURNAL; RAT; RAT STRAIN; REVIEW; STEREOTYPY; YAWNING;

EID: 0036287363     PISSN: 10288945     EISSN: None     Source Type: Journal    
DOI: 10.1080/10604450213042     Document Type: Review

References (78)

1. 4 dopamine receptor protein in the CNS using anti-receptor antisera
2. 3 receptor antagonists (+)-S 14297, nafadotride, GR 100,691 and 499194
3. 3 receptor antagonist PNU-99194A fails to block (+)-7-OH-DPAT substitution for D-amphetamine or cocaine
4. Neurotransmission and the central nervous system
5. 3 knockout and wild type mice
6. 2 receptor mRNA
7. 4 receptor antagonist, does not exhibit a neuroleptic-like profile in rodent behavioral tests
8. Interstriatial 3-methoxy-tyramine reflexes striatal dopamine release: An in vivo microdialysis study
9. 3 receptor-mediated events: DOPAC release in the striatum and some behavioral effects of quinpirole and 7-OH-DPAT in rats
10. Conformationally restricted congeners of dopamine derived from 2-aminoindan
11. 4 receptor and anxiety: Behavioural profiles of clozapine, L-745, 870 and L-741,742 in the mouse plus-maze
12. Serotoninergic and dopaminergic aspects of neuroleptic-induced extrapyramidal syndromes in non-human primates
13. 3 dopamine receptor antagonists using an ethiologically-based approach
14. 4 receptors coupled to adenylate cyclase
15. 4 antagonists on prepulse inhibition of acoustic startle and amphetamine stimulated locomotion in rats
16. Behavioral sequelae of dopaminergic degeneration: Postsynaptic supersensitivity, pre- and post-synaptic receptors
17. 3 receptor ligand
18. 4 dopamine receptor in rat brain
19. Modulation of striatal dopamine metabolism by the activity of dorsal raphe serotoninergic afferences
20. The action of chlorpromazine on exploration in pairs of rats
21. Clozapine
22. 3 receptor antagonist PNU 99194A on motor behavior and emotional reactivity in C57BL/6J mice
23. 3 (auto) receptor inhibits dopamine release in the frontal cortex of freely moving rats in vivo
24. 3 autoreceptors control synthesis and release in mesocortical and nigrostriatal pathways
25. Multiple receptors for dopamine
26. 3 preferring compounds in discrete areas of the rat brain
27. The rat brain
28. 3-mediated event?
29. Ontogenetic homologous supersensitization of quinpirole-induced yawning in rats
30. Low-dose quinpirole ontogenetically sensitizes to quinpirole-induced yawning in rats
31. Tyr-MIF-1 attenuates development of tolerance to spiperone-induced catalepsy in rats
32. 3 receptor binding affinities
33. 3 receptor sites in the brain. A comparative study using in situ hybridization histochemistry and ligand binding autoradiography
34. 3H-7-hydroxy-N,N-di-n-propyl-2-aminotetralin
35. Effect of haloperidol and sulpiride on dopamine metabolism in nucleus accumbens and olfactory tubercule: A study by in vivo voltametry
36. Simultaneous determination of dopamine, DOPAC and homovanillic acid. Direct injection of supernatants from brain tissue homogenates in a liquid chromatography-electrochemical detection system
37. 3 receptors
38. 4 receptor antagonists reverse apomorphine-induced blockade of prepulse inhibition
39. 4 receptor
40. 4 receptor selective antagonist
41. Mesolimbic 7-OH-DPAT affects locomotor activities in rats
42. Ionic composition of microdialysis perfusing solution alters the pharmacological responsiveness and basal outflow of striatal dopamine
43. 3 receptor
44. 2 receptors to mesostriatal regions of human forebrain
45. 4 antagonists administration to rats estimated by microdialysis technique
46. Microdialysis of the brain-modern technique for the studies of the central neurotransmitter systems
47. 4 and 5-hydroxytryptamine 2A receptor antagonist in rats
48. 4 receptor antagonist pyrrodin-3-yl]-thiazole (NRA 0045)
49. Comparison of some central effects of two dopamine agonists, quinpirole and 7-OH-DPAT in rats
50. The rat brain in stereotaxic coordinates
51. 3 receptors
52. 4 receptor
53. Regulation of dopamine release and metabolism in rat striatum in vivo: Effects of dopamine receptor antagonists
54. 3 receptor antagonist, SB-277011A
55. 4 receptors in the action and development of antipsychotic agents
56. 2 activity of R-(-)-apomorphine and selected analogs: A microdialysis study
57. 3 antagonist U-99194A maleate increases social behaviors of isolation-induced aggressive male mice
58. 3 receptor antagonist, activates locomotion in rodents
59. 4 receptor
60. Dopamine receptors and the dopamine hypothesis of schizophrenia
61. 3 dopamine receptor in cellular and organismal function
62. 2 receptor
63. 2 receptor to mesostriatal regions of human forebrain
64. 3 as a target for neuroleptics
65. 5) half a decade later
66. Substituted 3-phenyl piperidines: New centrally acting dopamine autoreceptor antagonists
67. 3 ligand R-(+)-7-OH-DPAT is independent of changes in dopamine release
68. 3 receptors
69. (+)-AJ76 and (+)-UH232: Central stimulants acting as preferential dopamine autoreceptor antagonists
70. 4 receptor with high affinity for antipsychotic clozapine
71. 3 receptor antagonists in regard to dopamine release, in vivo receptor displacement and behavior
72. 3-receptor: A postsynaptic receptor inhibitory on rat locomotor activity
73. 4 receptor ligands: Relation to antipsychotic action
74. 4 receptor antagonists
75. 3 receptors modulate evoked dopamine release from slices of rat nucleus accumbens via muscarinic receptors, but not from the striatum
76. 4-receptor analysis
77. In vivo measurement of dopamine and its metabolites by intracerebral dialysis: Changes after d-amphetamine
78. 4 dopamine antagonist with an in vitro and in vivo profile suggestive of an atypical antipsychotic