Dopamine D3 (auto)receptors inhibit dopamine release in the frontal cortex of freely moving rats in vivo

Journal of Neurochemistry

Volumn 66, Issue 5, 1996, Pages 2209-2212

  Gobert, A ^a   Lejeune, F ^a   Rivet, J M ^a   Cistarelli, L ^a   Millan, M J ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

Cortex; Dopamine D3 receptors; Electrophysiology; Microdialysis; PD 128,907; Ventral tegmental area

Indexed keywords

DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR BLOCKING AGENT; 2 NAPHTHYLAMINE; 3,4,4A,10B TETRAHYDRO 4 PROPYL 2H,5H (1)BENZOPYRANO(4,3 B) 1,4 OXAZIN 9 OL; 3,4,4A,10B-TETRAHYDRO-4-PROPYL-2H,5H-(1)BENZOPYRANO(4,3-B)-1,4-OXAZIN-9-OL; 7 (N,N DIPROPYLAMINO) 5,6,7,8 TETRAHYDRONAPHTHO(2,3 B)DIHYDRO 2,3 FURAN; 7-(N,N-DIPROPYLAMINO)-5,6,7,8-TETRAHYDRONAPHTHO(2,3-B)DIHYDRO-2,3-FURAN; BENZOPYRAN DERIVATIVE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; DRD3 PROTEIN, RAT; DRUG DERIVATIVE; FURAN DERIVATIVE; OXAZINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY MOVEMENT; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOPAMINE RELEASE; DRUG BINDING SITE; DRUG RECEPTOR BINDING; ELECTRIC ACTIVITY; ELECTROPHORESIS; FRONTAL CORTEX; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; VENTRAL TEGMENTUM; ANIMAL; DOSE RESPONSE; DRUG EFFECT; ELECTROPHYSIOLOGY; FRONTAL LOBE; MALE; METABOLISM; PHYSIOLOGY; TEGMENTUM; WISTAR RAT;

2-NAPHTHYLAMINE; ANIMALS; BENZOPYRANS; DOPAMINE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; FRONTAL LOBE; FURANS; MALE; MICRODIALYSIS; OXAZINES; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; TEGMENTUM MESENCEPHALI;

EID: 0029658999     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.66052209.x     Document Type: Article

References (18)

1. 3-preferring ligands act at synthesis modulating autoreceptors. J. Pharmacol. Exp. Ther. 274, 609-613.
2. 3 subtypes. Brain Res. 649, 95-110.
3. 2 receptor mRNA, Brain Res. 564, 203-219.
4. Ceci A., Baschirotto A., and Borsini F. (1994) The inhibitory effect of 8-OH-DPAT on the firing of dorsal raphe serotoninergic neurons in rats is attenuated by lesion of the frontal cortex. Neuropharmacology 33, 709-713.
5. 3 receptor ligand. Eur. J. Pharmacol. 249, R9-R10.
6. 3 receptor in the rat brain. Neuroscience 65, 731-745.
7. 3 autoreceptors control synthesis and release in mesolimbic, mesocortical and nigrostriatal pathways. J. Pharmacol. Exp. Ther. 275, 899-913.
8. 3 autoreceptors inhibits firing of ventral tegmental dopaminergic neurones in vivo. Eur. J. Pharmacol. 275, R7-R9.
9. 3H]-7-hydroxy-N,N-di-n-propyl-2-aminotetralin. Proc. Natl. Acad. Sci. USA 89, 8155-8159.
10. 2 receptors elicits prolactin secretion and catalepsy. J. Pharmacol. Exp. Ther. 275, 885-898.
11. Ozaki N., Nakahara D., Miura H., Kasahara Y., and Nagatsu T. (1989) Effect of apomorphine on in vivo release of dopamine and its metabolites in the prefrontal cortes and the striatum, studied by a microdialysis method. J. Neurochem. 53, 1861-1864.
12. 3 dopamine receptor mRNA in rat brain using a ribonuclease protection assay. Mol. Brain Res. 33, 97-103.
13. Roth R. H. and Elsworth J. D. (1995) Biochemical pharmacology of midbrain dopamine neurons, in Psychopharmacology: The Fourth Generation of Progress (Bloom E. and Kupfer D., eds), pp. 227-243. Raven Press, New York.
14. Santiago M., Machado A., and Cano J. (1993) Regulation of prefrontal cortical dopamine release by dopamine receptor agonists and antagonists. Eur. J. Pharmacol. 239, 83-91.
15. 2 receptors. Neuroreport 6, 329-332.
16. Sokoloff P. and Schwartz J.-C. (1995) Novel dopamine receptors half a decade later. Trends Pharmacol. Sci. 16, 270-275.
17. Tanda G., Carboni E., Frau R., and Di Chiara G. (1994) Increase of extracellular dopamine in the prefrontal cortex: a trait of drugs with antidepressant potential? Psychopharmacology 115, 285-288.
18. 3 receptors inhibit dopamine release. J. Pharmacol. Exp Ther. 270, 475-479.