Thienopyrimidine derivatives prevent cartilage destruction in articular disease

Farmaco

Volumn 56, Issue 12, 2001, Pages 959-964

  Panico, Annamaria ^a   Cardile, Venera ^a   Santagati, Andrea ^a   Gentile, Barbara ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Cartilage; GAGs; IL 1 ; NO; Thienopyrimidines

Indexed keywords

GLYCOSAMINOGLYCAN; INTERLEUKIN 1BETA; NITRIC OXIDE; PYRIMIDINE DERIVATIVE; INTERLEUKIN 1; SULFIDE; THIENOPYRIMIDINE;

ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARTILAGE DEGENERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; DRUG SYNTHESIS; INFRARED RADIATION; NONHUMAN; NOSE CARTILAGE; PROTON NUCLEAR MAGNETIC RESONANCE; SWINE; ANIMAL; ARTICULAR CARTILAGE; CHONDROPATHY; DOSE RESPONSE; METABOLISM; PATHOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; CARTILAGE DISEASES; CARTILAGE, ARTICULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOSAMINOGLYCANS; INTERLEUKIN-1; NITRIC OXIDE; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFIDES; SWINE;

EID: 0035661128     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(01)01149-1     Document Type: Article

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