Regulation of the ryanodine receptor in heart failure

Basic Research in Cardiology, Supplement

Volumn 97, Issue 1, 2002, Pages

  Marx, Steven O ^a   Marks, Andrew R ^a  

^a College of Physicians and Surgeons ^*  (United States)

Author keywords

Calcium; Heart failure; Ion channel; Phosphorylation; Ryanodine receptor

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM CHANNEL; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; FKBP 12.6 PROTEIN; REGULATOR PROTEIN; RYANODINE RECEPTOR; RYANODINE RECEPTOR 2; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CARDIOMYOPATHY; CYTOPLASM; DRUG EFFECT; DRUG TOLERABILITY; ENDOPLASMIC RETICULUM; ENZYME PHOSPHORYLATION; EXCITATION CONTRACTION COUPLING; HEART ARRHYTHMIA; HEART ASSIST DEVICE; HEART CONTRACTION; HEART FAILURE; HEART MUSCLE POTENTIAL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PROTEIN STRUCTURE; REGULATORY MECHANISM; REVIEW; SARCOPLASMIC RETICULUM;

ANIMALS; CALCIUM; CARDIAC OUTPUT, LOW; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HUMANS; PHOSPHORYLATION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

EID: 0036282247     PISSN: 01759418     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (26)

1. Cross-signaling between L-type Ca2+ channels and ryanodine receptors in rat ventricular myocytes
2. Coordinated feet and the dance of ryanodine receptors
3. Bell-shaped calcium response curves of Ins (1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum
4. Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein
5. Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum
6. Afterdepolarizations and triggered activity
7. Differential regulation of two types of intracellular calcium release channel during end-stage heart failure
8. Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure
9. Regulation of the cardiac ryanodine receptor channel by luminal Ca2+ involves luminal Ca2+ sensing sites
10. Calcium handling proteins in the failing human heart
11. Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure
12. Dyssynchronous Ca(2+) sparks in myocytes from infarcted hearts
13. Cellular functions of immunophilins
14. Intracellular calcium-release channels: Regulators of cell life and death
15. Cardiac intracellular calcium release channels: Role in heart failure
16. Ryanodine receptors/calcium release channels in heart failure and sudden cardiac death
17. Coupled gating between cardiac calcium release channels (Ryanodine Receptors)
18. 2+ release channels (ryanodine receptors)
19. Phosphorylation-dependent regulation of ryanodine receptors: A novel role for leucine/isoleucine zippers
20. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
21. Regulation of calcium release is gated by calcium current, not gating charge, in cardiac, myocytes
22. The ryanodine receptor from canine heart sarcoplasmic reticulum is associated with a novel FK-506 binding protein
23. Regulation of cardiac muscle Ca2+ release channel by sarcoplasmic reticulum lumenal Ca2+
24. A-kinase anchoring protein 100 (AKAP100) is localized in multiple subcellular compartments in the adult rat heart
25. Protection of ischemic rat heart by dantrolene, an antagonist of the sarcoplasmic reticulum calcium release channel