Decreased levels of N-acetylaspartate in dorsolateral prefrontal cortex in a case of intractable severe sympathetically mediated chronic pain (complex regional pain syndrome, type I)

Brain and Cognition

Volumn 49, Issue 1, 2002, Pages 102-113

  Grachev, Igor D ^a   Thomas, P Sebastian ^a   Ramachandran, Tarakad S ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

Complex regional pain syndrome type I; Myo inositol; N acetylaspartate; Prefrontal cortex; Proton magnetic resonance spectroscopy; Reflex sympathetic dystrophy

Indexed keywords

INOSITOL; N ACETYLASPARTIC ACID;

ADULT; AFFECT; ANXIETY; ARTICLE; CASE REPORT; CHRONIC PAIN; CINGULATE GYRUS; COMPLEX REGIONAL PAIN SYNDROME; CONTROLLED STUDY; DEPRESSION; FEMALE; HUMAN; MOOD; NERVE DEGENERATION; NOCICEPTION; ORBITAL CORTEX; PAIN ASSESSMENT; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; THALAMUS;

EID: 0036275979     PISSN: 02782626     EISSN: None     Source Type: Journal    
DOI: 10.1006/brcg.2001.1489     Document Type: Article

References (60)

1. New directions for studying human brain pathophysiology of chronic pain states
2. Deficits in striatal dopamine D(2) receptors and energy metabolism detected by in vivo microPET imaging in a rat model of Huntington's disease
3. Biochemical hypotheses of mood and anxiety disorders
4. Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder
5. Mechanism of action of deep brain stimulation
6. Neural and development actions of lithium: A unifying hypothesis
7. The treatment of hyperalgesia following neural injury
8. Proton MR spectroscopy in neoplastic and non-neoplastic brain disorders
9. Global cerebral blood flow decreases during pain
10. Activation of the anterior cingulate cortex by thalamic stimulation in patients with chronic pain: A positron emission tomography study
11. Meta-analysis of thirty-four independent samples studied using PET reveals a significantly attenuated central response to noxious stimulation in clinical pain patients
12. Chronic pain: A PET study of the central effects of percutaneous high cervical cordotomy
13. Subgenual prefrontal cortex abnormalities in mood
14. Functional neuroimaging studies of depression: The anatomy of melancholia
15. N-Acetylaspartic acid (NAA) and N-acetylaspartylglutamic acid (NAAG) in human ventricular, subarachnoid, and lumbar cerebrospinal fluid
16. Phosphoinositides
17. Anxiety in healthy humans is associated with orbital frontal chemistry
18. Abnormal brain chemistry in chronic back pain: An in vivo proton magnetic resonance spectroscopy study
19. Dissociating anxiety from pain: Mapping the neuronal marker N-acetylaspartate to perception distinguishes closely interrelated characteristics of chronic pain
20. 1H nuclear magnetic resonance spectroscopic imaging of neuronal loss in rat brain
21. Cenral representation of chronic ongoing neuropathic pain studied by positron emission tomography
22. Right-lateralised central processing for pain of nitroglycerin-induced cluster headache
23. Unilateral decrease in thalamic activity observed with positron emission tomography in patients with chronic neuropathic pain
24. Statistical parametric mapping with 18F-dopa PET shows bilaterally reduced striatal and nigral dopaminergic function in early Parkinson's disease
25. Spinal cord stimulation in patients with chronic reflex sympathetic dystrophy
26. Angiotensin-converting enzyme gene polymorphism in patients with neuropathic pain
27. Sympathetically maintained chronic pain (RSD) is a hyperfrontal condition
28. Deep brain stimulation for intractable pain: A 15-years experience
29. Positron emission tomography study of a chronic pain patient successfully treated with somatosensory thalamic stimulation
30. Neurophysiological investigation of the basis of the fMRI signal
31. Neuroplasticity and cellular resilience in mood disorders
32. Striatal dopaminergic metabolism is increased by deep brain stimulation of the subthalamic nucleus in 6-hydroxydopamine lesioned rats
33. The short-form McGill Pain Questionnaire
34. 1H MR spectroscopic imaging and regional cerebral glucose metabolism in Alzheimer's disease
35. 1H NMR spectroscopy: N-acetyl-L-aspartate, creatine, and choline
36. Myo-Inositol correlates with mood in bipolar disorder
37. Allodynia after lateral-medullary (Wallenberg) infarct: A PET study
38. Parietal and cingulate processes in central pain: A combined positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) study of an unusual case
39. Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression
40. Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells
41. Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder
42. Regional cerebral blood flow measured during symptom provocation in obsessive-compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography
43. Thalamic stimulation and functional magnetic resonance imaging: Localization of cortical and subcortical activation with implanted electrodes
44. Central nervous pathways mediating angina pectoris
45. Functional brain circuits in major depression and remission
46. Reduced frontal cortex inositol levels in postmortem brain of suicide victims and patients with bipolar disorder
47. The functional neuroanatomy of mood disorders
48. Studies on the distribution of N-acetyl-L-aspartate acid in brain
49. The cortical representation of pain
50. Cortical representation of pain: Functional characterization of nociceptive areas near the lateral sulcus
51. Energy hypometabolism in posterior cingulate cortex of alzheimer's patients: Superficial laminar cytochrome oxidase associated with disease duration
52. Brain stem activation in spontaneous human migraine attacks
53. Alternative diagnostic criteria for major depressive disorder in patients with chronic pain
54. Decreased dorsolateral prefrontal N-acetyl aspartate in bipolar disorder