Agonist-directed trafficking explaining the difference between response pattern of naratriptan and sumatriptan in rabbit common carotid artery

British Journal of Pharmacology

Volumn 136, Issue 2, 2002, Pages 171-176

  Akin, Demet ^a   Onaran, H Ongun ^a   Gurdal, Hakan ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Adenylate cyclase inhibition; Cyclic AMP; Naratriptan; Rabbit common carotid artery; Sumatriptan; Vascular contractions

Indexed keywords

3 [4 (3 CHLOROPHENYL) 1 PIPERAZINYL] 1,1 DIPHENYL 2 PROPANOL; ADENYLATE CYCLASE; CYCLIC AMP; ELETRIPTAN; FORSKOLIN; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; NARATRIPTAN; PERTUSSIS TOXIN; PRAZOSIN; RECEPTOR SUBTYPE; SB 216641; SEROTONIN; SEROTONIN 1B RECEPTOR; SEROTONIN 1D RECEPTOR; SUMATRIPTAN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; COMMON CAROTID ARTERY; CONTROLLED STUDY; DRUG INHIBITION; DRUG RECEPTOR BINDING; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; RABBIT; SIGNAL TRANSDUCTION;

ANIMALS; CAROTID ARTERY, COMMON; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOLES; PIPERIDINES; PROTEIN TRANSPORT; RABBITS; SEROTONIN AGONISTS; SUMATRIPTAN; TRYPTAMINES; VASOCONSTRICTION;

EID: 0036275605     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704710     Document Type: Article

References (17)

1. 5-Hydroxytryptamine (1F) receptors do not participate in vasoconstriction: Lack of vasoconstriction to LY344864, a selective serotonin (1F) receptor agonist in rabbit saphenous vein
2. 1B receptor in the rabbit carotid artery
3. The interaction of serotonergic agonists with α-adrenoceptors in rabbit aorta
4. VIIth International Union of Pharmacology classification of receptors for 5-hydroxytryptamine
5. The classification of drug and drug receptors in isolated tissues
6. Agonist-receptor efficacy II: Agonist trafficking of receptor signals
7. Coronary side-effect potential of current and prospective antimigraine drugs
8. Contractile 5-HT1B receptors in human cerebral arteries: Pharmacological characterization and localization with immunocytochemistry
9. Human serotonin 1B receptor expression in Sf9 cells: Phosphorylation, palmitoylation, and adenylyl cyclase inhibition
10. Selective antagonism of human 5HT1D and 5HT1B receptor-mediated responses in stably transfectd C6-glial cells by ketanserin and GR127,935
11. SB-216641 and BRL-15572-compounds to pharmacologically discriminate h5-HT1B and h5HT1D receptors
12. Bovine isolated middle cerebral artery contractions to antimigraine drugs
13. Evidence for 5HT1Dβ but not 5-HT1Dα receptor subtype in canine large coronary arteries and saphenous vein
14. Allosteric equilibrium model explains steady-state coupling of β-adrenergic receptors to adenylate cyclase in turkey erythrocyte membranes
15. Expression of serotonin receptor mRNAs in blood vessels
16. Recombinant saphenous vein 5HTlb receptors of the rabbit: Comparative pharmacology with human 5-HT1B receptors
17. Dual coupling of cloned human 5-hydroxytryptaminelda and 5-hydroxytripta-mine1db receptors stably expressed in murine fibroblasts: Inhibition of adenylate cyclase and elevation of intracellular calcium concentrations via pertusis toxin sensitive G protein(s)